2. Natural Products
  3. Plants
  4. Nyssaceae

Nyssaceae

 

Nyssaceae (24):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-16560
    Camptothecin 7689-03-4 99.77%
    Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.
    Camptothecin
  • HY-13768A
    Topotecan hydrochloride 119413-54-6 99.89%
    Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities.
    Topotecan hydrochloride
  • HY-16562A
    Irinotecan hydrochloride 100286-90-6 99.89%
    Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer.
    Irinotecan hydrochloride
  • HY-N0095
    (S)-10-Hydroxycamptothecin 19685-09-7 99.74%
    (S)-10-Hydroxycamptothecin (10-HCPT;10-Hydroxycamptothecin) is a DNA topoisomerase I inhibitor of isolated from the Chinese plant Camptotheca accuminata. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis-inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia treatment.
    (S)-10-Hydroxycamptothecin
  • HY-100309
    9-Aminocamptothecin 91421-43-1 98.89%
    9-Aminocamptothecin (9-Amino-CPT) is a topoisomerase I inhibitor with potent anticancer activity.
    9-Aminocamptothecin
  • HY-N17569
    3β-O-trans-Feruloyl-2α,23α-dihydroxy-urs-12-en-28-oic acid 2002478-95-5
    3β-O-trans-Feruloyl-2α,23α-dihydroxy-urs-12-en-28-oic acid (Compound 3) is a pentacyclic triterpenoid found in the fruit of Camptotheca acuminata.
    3β-O-trans-Feruloyl-2α,23α-dihydroxy-urs-12-en-28-oic acid
  • HY-N12944
    18-Hydroxycamptothecin 116139-46-9
    18-Hydroxycamptothecin is a camptothecin analogue that can be isolated from Camptotheca acuminata. Camptothecin compounds possess potential activities such as anti-cancer and anti-viral properties.
    18-Hydroxycamptothecin
  • HY-N6011
    9-Methoxycamptothecin 39026-92-1 99.13%
    9-Methoxycamptothecin (MCPT), isolated from Camptotheca acuminata, has antitumor activities through topoisomerase inhibition. 9-Methoxycamptothecin (MCPT) induces strong G2/M arrest and apoptosis in cancer.
    9-Methoxycamptothecin
  • HY-13744
    Rubitecan 91421-42-0 99.41%
    Rubitecan (RFS 2000), a Camptothecin derivative, is an orally active topoisomerase I inhibitor with broad antitumor activity, and induces protein-linked DNA single-strand breaks, thereby blocking DNA and RNA synthesis in dividing cells.
    Rubitecan
  • HY-N2108
    7-Ethylcamptothecin 78287-27-1 99.58%
    7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a DNA topoisomerase I inhibitor that exhibits significant antitumor activity against tumor cells. 7-Ethylcamptothecin serves as a key precursor for the synthesis of 20 (S)-O-substituted benzoyl-7-ethylcamptothecin compounds. 7-Ethylcamptothecin is widely used in various tumor-related scientific studies.
    7-Ethylcamptothecin
  • HY-N8533
    Sodium Camptothecin 25387-67-1
    Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.
    Sodium Camptothecin
  • HY-N0275
    (±)-10-Hydroxycamptothecin 64439-81-2 99.57%
    (±)-10-Hydroxycamptothecin is an indole alkaloid that inhibits the activity of topoisomerase I and has a broad spectrum of anticancer activity.
    (±)-10-Hydroxycamptothecin
  • HY-N8698
    Picein 530-14-3 99.98%
    Picein is an antioxidant and anti-inflammatory agent. Picein can be isolated from the leaves of Picrorhiza kurroa. Picein reduces MDA levels and increases the levels of SOD, GPX and TAC. Picein alleviates oxidative stress and promotes bone regeneration in osteoporotic bone defects by inhibiting Ferroptosis (via activation of the Nrf2/HO-1/GPX4 pathway). Picein prevents scopolamine (HY-N0296)-induced passive avoidance memory impairment in rats. Picein can be used in research related to osteoporotic bone defects and Alzheimer's disease.
    Picein
  • HY-N0446
    10-Methoxycamptothecin 19685-10-0 98.06%
    10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata, and has been confirmed to possess high anti-cancer properties. 10-Methoxycamptothecin has higher cytotoxicity than 10-hydroxycamptothecin by testing antitumor activity against 2774 cell lines.
    10-Methoxycamptothecin
  • HY-W897655
    20-O-Acetylcamptothecin 7688-64-4 98.0%
    20-O-Acetylcamptothecin (O-Acetylcamptothecin) is a derivative of Camptothecin (HY-16560) and an inhibitor of Topoisomerase I.
    20-O-Acetylcamptothecin
  • HY-16560R
    Camptothecin (Standard) 7689-03-4
    Camptothecin (Standard) (Campathecin (Standard)) is the analytical standard of Camptothecin (HY-16560). This product is intended for research and analytical applications. Camptothecin (CPT), a kind of alkaloid, is a DNA topoisomerase I (Topo I) inhibitor with an IC50 of 679 nM. Camptothecin (CPT) exhibits powerful antineoplastic activity against colorectal, breast, lung and ovarian cancers, modulates hypoxia-inducible factor-1α (HIF-1α) activity by changing microRNAs (miRNA) expression patterns in human cancer cells.
    Camptothecin (Standard)
  • HY-N0446R
    10-Methoxycamptothecin (Standard) 19685-10-0
    10-Methoxycamptothecin (Standard) is the analytical standard of 10-Methoxycamptothecin. This product is intended for research and analytical applications. 10-Methoxycamptothecin is a natural bioactive derivative of camptothecin (CPT) isolated from Camptotheca acuminata, and has been confirmed to possess high anti-cancer properties. 10-Methoxycamptothecin has higher cytotoxicity than 10-hydroxycamptothecin by testing antitumor activity against 2774 cell lines.
    10-Methoxycamptothecin (Standard)
  • HY-16562AR
    Irinotecan hydrochloride (Standard) 100286-90-6
    Irinotecan (hydrochloride) (Standard) is the analytical standard of Irinotecan (hydrochloride). This product is intended for research and analytical applications. Irinotecan hydrochloride ((+)-Irinotecan hydrochloride) is a topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer.
    Irinotecan hydrochloride (Standard)
  • HY-N8698R
    Picein (Standard) 530-14-3
    Picein (Standard) is the analytical standard of Picein. This product is intended for research and analytical applications. Picein, isolated from Picrorhiza kurroa, is a naturally occurring antioxidant.
    Picein (Standard)
  • HY-N2108R
    7-Ethylcamptothecin (Standard) 78287-27-1
    7-Ethylcamptothecin (Standard) is the analytical standard of 7-Ethylcamptothecin (HY-N2108). This product is intended for research and analytical applications. 7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a key intermediate in the synthesis of SN-38 (HY-13704). 7-Ethylcamptothecin can be used in tumor-related research.
    7-Ethylcamptothecin (Standard)