Camptothecoside
Camptothecoside is a novel indole glycoside isolated from the fruits of Camptotheca acuminata, and it serves as a biosynthetic intermediate of camptothecin. Camptothecoside shares the same four-ring conjugated system (rings A-D) as camptothecin, but it has a ketal glycoside structure (ring E) at the C-21 position, with a β-D-glucopyranosyl group linked to the C-21 position. Camptothecoside can be used in studies on camptothecin biosynthesis and natural product chemistry.
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- CAS No.: 1914972-40-9
- 화학식: C26H26N2O8
- 분자량:494.49
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Camptothecoside (50 μM; 48 h) exhibits weak in vitro cytotoxicity against human hepatoma HepG2, human breast carcinoma MCF-7, and human osteosarcoma U2-OS cells at a concentration of 50 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human hepatoma HepG2 cells, human breast carcinoma MCF-7 cells, human osteosarcoma U2-OS cells
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Concentration:50 μM
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Incubation Time:48 h
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Result:Showed weak cytotoxicity against all three tested cell lines at the highest tested concentration of 50 μM.
Chemical Information
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CAS No. 1914972-40-9
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분자량 494.49
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화학식 C26H26N2O8
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SMILES
O=C1N2C(C3=NC4=CC=CC=C4C=C3C2)=CC5=C1CO[C@H]([C@@H]5C=C)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)CO
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)