1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. Sodium Camptothecin

Sodium Camptothecin 

Cat. No.: HY-N8533
Handling Instructions

Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA.

For research use only. We do not sell to patients.

Sodium Camptothecin Chemical Structure

Sodium Camptothecin Chemical Structure

CAS No. : 25387-67-1

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Description

Sodium Camptothecin is a plant alkaloid, with antitumor activity. Sodium Camptothecin is a reversible inhibitor of RNA synthesis. Sodium Camptothecin is an effective inhibitor of adenovirus replication. Sodium Camptothecin inhibits DNA synthesis and causes breaks in intracellular preformed viral DNA[1][2].

In Vitro

Sodium Camptothecin (5 μM; 10 min) causes a severe inhibition of heterogeneously sedimenting nuclear RNA (HnRNA) synthesis[1].
Sodium Camptothecin also blocks a specific step in the processing of ribosomal precursor RNA, allowing the conversion of 45S RNA to 32S RNA, but inhibiting the conversion of 32S RNA to 28S RNA [1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

388.35

Formula

C₂₀H₁₇N₂NaO₅

CAS No.
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Please store the product under the recommended conditions in the Certificate of Analysis.

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Sodium Camptothecin
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HY-N8533
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