530-14-3
Chemical Structure
Picein
- CAS No.: 530-14-3
- Formula:C14H18O7
- Molecular Weight:298.29
IUPAC Name: 1-(4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)phenyl)ethan-1-one
InChIKey: GOZCEKPKECLKNO-RKQHYHRCSA-N
SMILES: O[C@H]([C@H]([C@@H]([C@H](O1)CO)O)O)[C@@H]1OC2=CC=C(C=C2)C(C)=O
Biological Activity: Picein is an antioxidant and anti-inflammatory agent. Picein can be isolated from the leaves of Picrorhiza kurroa. Picein reduces MDA levels and increases the levels of SOD, GPX and TAC. Picein alleviates oxidative stress and promotes bone regeneration in osteoporotic bone defects by inhibiting Ferroptosis (via activation of the Nrf2/HO-1/GPX4 pathway). Picein prevents scopolamine (HY-N0296)-induced passive avoidance memory impairment in rats. Picein can be used in research related to osteoporotic bone defects and Alzheimer's disease[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Picein | 99.98% | Picein is an antioxidant and anti-inflammatory agent. Picein can be isolated from the leaves of Picrorhiza kurroa. Picein reduces MDA levels and increases the levels of SOD, GPX and TAC. Picein alleviates oxidative stress and promotes bone regeneration in osteoporotic bone defects by inhibiting Ferroptosis (via activation of the Nrf2/HO-1/GPX4 pathway). Picein prevents scopolamine (HY-N0296)-induced passive avoidance memory impairment in rats. Picein can be used in research related to osteoporotic bone defects and Alzheimer's disease. | ||||||||||||||||||||
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Picein (Standard) | ≥98% | Picein (Standard) is the analytical standard of Picein. This product is intended for research and analytical applications. Picein, isolated from Picrorhiza kurroa, is a naturally occurring antioxidant. | ||||||||||||||||||||
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- [1]. Huang L, et al. Picein alleviates oxidative stress and promotes bone regeneration in osteoporotic bone defect by inhibiting ferroptosis via Nrf2/HO-1/GPX4 pathway. Environ Toxicol. 2024;39(7):4066-4085. [Content Brief]
- [2]. Kant K, et al. Evaluation of Antioxidant Activity of Picrorhiza kurroa (Leaves) Extracts. Indian J Pharm Sci. 2013;75(3):324-329. [Content Brief]
- [3]. Elyasi L, et al. The Effect of Picein on Inhibitory Avoidance Memory and Activity of Antioxidant Enzymes in Hippocampus of Male Rats with Scopolamine-Induced Injury. Mol Neurobiol. 2025;62(6):7835-7845. [Content Brief]
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