20-O-Acetylcamptothecin
Based on 1 Customer Validation
20-O-Acetylcamptothecin (O-Acetylcamptothecin) is a derivative of Camptothecin (HY-16560) and an inhibitor of Topoisomerase I.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 7688-64-4
- Formula: C22H18N2O5
- Molecular Weight:390.39
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Topoisomerase Isoforms
More
Biological Activity
|
Topoisomerase I |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
0.39 μM
Compound: 16
|
Concentration that inhibits the proliferation of L1210 cells by 50%
Concentration that inhibits the proliferation of L1210 cells by 50%
|
[PMID: 2537428] |
Chemical Information
-
CAS No. 7688-64-4
-
Appearance Solid
-
Molecular Weight 390.39
-
Formula C22H18N2O5
-
Color White to off-white
-
SMILES
CC(O[C@]1(C2=C(COC1=O)C(N3C(C4=NC5=CC=CC=C5C=C4C3)=C2)=O)CC)=O
-
Synonyms
O-Acetylcamptothecin
-
Structure Classification
-
Initial Source
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (273 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)