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Inhibitors, Agonists & Compound Libraries

Antibody-drug Conjugate/ADC Related

The antibody-drug conjugate (ADC) is a humanized or human monoclonal antibody conjugated with highly cytotoxic small molecules (payloads) through chemical linkers. ADCs increase the cell-killing potential of monoclonal antibodies (mAbs), and confer higher tumor selectivity. Some ADCs has been approved by FDA.

PROTAC

PROTACs or Proteolysis Targeting Chimeric Molecules are heterobifunctional nanomolecules that theoretically target any protein for ubiquitination and degradation. PROTACs consist of one moiety which is recognized by the E3 ligase. This moiety is then chemically and covalently to a small molecule or a protein that recognizes the target protein. The trimeric complex formation leads to the transfer of ubiquitins to the target protein.

Compound Screening Libraries

10,000+ small molecules with validated biological and pharmacological activities.

80+ ready-to-use bioactive libraries.

40+ screening libraries (6 million compounds).

Provides LC / MS or NMR reports for each compound to ensure high quality.

Customize Your Library :

You can select compounds, format (powder/liquid), container and plate map depending on your requirements.

Customized libraries are also included in this spring sale.