1. Protein Tyrosine Kinase/RTK
  2. c-Fms
  3. PLX5622

PLX5622 

Cat. No.: HY-114153
Handling Instructions

PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals.

For research use only. We do not sell to patients.

PLX5622 Chemical Structure

PLX5622 Chemical Structure

CAS No. : 1303420-67-8

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Description

PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor, for extended and specific microglial elimination, preceding and during pathology development. PLX5622 demonstrates desirable PK properties in varies animals[1].

IC50 & Target

CSF1R[1].

Molecular Weight

395.41

Formula

C₂₁H₁₉F₂N₅O

CAS No.

1303420-67-8

SMILES

COC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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PLX5622
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HY-114153
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