1. Protein Tyrosine Kinase/RTK
  2. c-Fms
    c-Kit
  3. DCC-3014

DCC-3014 

Cat. No.: HY-136256
Handling Instructions

DCC-3014 is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively.

For research use only. We do not sell to patients.

DCC-3014 Chemical Structure

DCC-3014 Chemical Structure

CAS No. : 1628606-05-2

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Description

DCC-3014 is a c-FMS (CSF-IR) and c-Kit dual inhibitor extracted from patent WO2014145025A2, Compound Example 10, has IC50s of <0.01 μM and 0.1-1 μM, respectively[1].

IC50 & Target

IC50: <0.01 μM (c-FMS/CSF-IR), 0.1-1 μM (c-Kit)[1]

In Vitro

DCC-3014 is a c-FMS (CSF-IR) and c-Kit dual inhibitor with anti-cancer and anti-proliferative activities[1].

Molecular Weight

431.49

Formula

C₂₃H₂₅N₇O₂

CAS No.

1628606-05-2

SMILES

O=C1N(C)C(NC(C)C)=NC=C1C2=NC(C)=C(OC3=CC(C4=CN(C)N=C4)=NC=C3)C=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

DCC-3014DCC3014DCC 3014c-Fmsc-KitCSF-1 receptorcolony stimulating factor 1 receptorCSF-1RCSF1RSCFRCD117Inhibitorinhibitorinhibit

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