Search Result

Results for "

aldehydes

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Aldehyde Dehydrogenase (ALDH) (22) ADC Linker (6) Aldose Reductase (2) Apoptosis (11) Autophagy (1) Bacterial (3) Beta-secretase (1) Biochemical Assay Reagents (8) c-Met/HGFR (5) Caspase (2) Cathepsin (1) COX (1) Cuproptosis (1) DNA Stain (1) DNA/RNA Synthesis (3) Drug-Linker Conjugates for ADC (2) Endogenous Metabolite (9) Epigenetic Reader Domain (1) Fluorescent Dye (22) Glucosidase (1) Histone Methyltransferase (2) HSV (1) Interleukin Related (1) IRE1 (1) Isotope-Labeled Compounds (2) JAK (1) Liposome (4) Mitochondrial Metabolism (2) Molecular Glues (1) Notch (1) Parasite (2) Phosphodiesterase (PDE) (2) Prolyl Endopeptidase (PREP) (1) PROTAC Linkers (8) Proteasome (3) Pyroptosis (1) Reactive Oxygen Species (3) Sodium Channel (1) STAT (1) γ-secretase (1)
By Research Areas:	Cancer (56) Cardiovascular Disease (3) Infection (7) Inflammation/Immunology (7) Metabolic Disease (12) Neurological Disease (6)
Click Chemistry:	ADC Synthesis (5) TCO (2) DBCO (1) PROTAC Synthesis (3) Azide (2) Tetrazine (2) Alkynes (1)

134

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Aldehyde Dehydrogenase (ALDH)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2947

ALDH Aldehyde dehydrogenase (NAD(P))	Aldehyde Dehydrogenase (ALDH)	Others
ALDH (Aldehyde dehydrogenase (NAD(P))) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The ALDHs are one of many enzyme systems the body utilizes to alleviate aldehyde stress .

HY-126003

ALDH1A1-IN-2	Aldehyde Dehydrogenase (ALDH)	Cancer
ALDH1A1-IN-2 is a potent inhibitor of aldehyde dehydrogenase 1a1 (aldh1a1). Aldehyde dehydrogenases (ALDH) constitute a family of enzymes that play a critical role in oxidizing various cytotoxic xenogenic and biogenic aldehydes. ALDH1A1-IN-2 has the potential for the research of cancer, inflammation, or obesity (extracted from patent WO2019089626A1, compound 295) .

HY-D1481

6,7-Diaminoquinoxaline-2,3-dione dihydrochloride

Fluorescent Dye Others

6,7-Diaminoquinoxaline-2,3-dione dihydrochloride is a fluorescent dye that reacts with aldehydes .

6,7-Diaminoquinoxaline-2,3-dione dihydrochloride	Fluorescent Dye	Others
6,7-Diaminoquinoxaline-2,3-dione dihydrochloride is a fluorescent dye that reacts with aldehydes .

HY-P4308

*Z-Pro-Pro-aldehyde-dimethyl acetal*	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-157794

6-Nitroquinazoline

Parasite Infection

6-Nitroquinazoline is an antimalarial agent. 6-Nitroquinazoline is also a substrate for human liver aldehyde oxidase .
HY-N8016

Nonanal

Others Metabolic Disease Inflammation/Immunology

Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity .
HY-W004305

Hexadecanal

Palmitaldehyde
Endogenous Metabolite Metabolic Disease

Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals .

6-Nitroquinazoline	Parasite	Infection
6-Nitroquinazoline is an antimalarial agent. 6-Nitroquinazoline is also a substrate for human liver aldehyde oxidase .

Nonanal	Others	Metabolic Disease Inflammation/Immunology
Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity .

Hexadecanal Palmitaldehyde	Endogenous Metabolite	Metabolic Disease
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals .

HY-135136

Aldehyde reactive probe TFA	Biochemical Assay Reagents	Others
Aldehyde reactive probe (TFA) is a biotinylated reagent for the detection and quantification of AP sites in damaged DNA .

HY-137100

Cy 5 hydrazide Cyanine5 hydrazide	Fluorescent Dye	Others
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .

HY-138064

4-APC hydrobromide	Others	Others
4-APC hydrobromide is a highly sensitive and selective derivatization agent for aldehydes. 4-APC hydrobromide possesses an aniline moiety for a fast selective reaction with aliphatic aldehydes as well as a quaternary ammonium group for improved MS sensitivity. 4-APC hydrobromide allows highly sensitive and selective MS detection of aldehydes .

HY-20003

(-)-Corey lactone benzoate

Others Others

(-)-Corey lactone benzoate is a building block in the chemical synthesis of corey aldehyde .

(-)-Corey lactone benzoate	Others	Others
(-)-Corey lactone benzoate is a building block in the chemical synthesis of corey aldehyde .

HY-108680

Carbazeran citrate	Phosphodiesterase (PDE)	Metabolic Disease
Carbazeran (citrate), a potent phosphodiesterase inhibitor, is aldehyde oxidase substrate. Carbazeran (citrate) can be used for the research of metabolic disease .

HY-151690

FAM hydrazide, 6-isomer	Fluorescent Dye	Others
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .

HY-132264

FAM hydrazide, 6-isomer hydrochloride	Fluorescent Dye	Others
FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .

HY-147240

Acloproxalap ADX-629	Others	Infection Cardiovascular Disease Inflammation/Immunology
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes .

HY-D1882

Cy5.5 hydrazide

Fluorescent Dye Others

Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .

Cy5.5 hydrazide	Fluorescent Dye	Others
Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .

HY-D1667

BDP 558/568 hydrazide	Fluorescent Dye	Others
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.

HY-151774

TAMRA hydrazide (6-isomer)	Fluorescent Dye	Others
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .

HY-122782

Lucidal Lucialdehyde C	Glucosidase	Metabolic Disease Cancer
Lucidal (Lucialdehyde C) is a natural lanostante-type triterpene aldehyde that shows inhibitory effects against α-glucosidase (Glucosidase) with an IC₅₀ of 0.635 mM. Lucidal has anticancer and antidiabetic effects .

HY-D1604

BODIPY FL Ethylamine	Fluorescent Dye	Others
BODIPY FL Ethylamine is a fluorescent dye that reversibly reacts with aldehyde/ketone to yield a Schiff base. BODIPY FL Ethylamine can be reduced to form a stable amine derviative using sodium borohydride or sodium cyanoborohydride .

HY-120893

trans-4,5-Epoxy-(E)-2-decenal	Others	Others
trans-4,5-Epoxy-(E)-2-decenal is an oxygenated α,β-unsaturated aldehyde found in mammalian blood that gives blood its characteristic metallic odor. It is used by predators to locate blood or prey .

HY-136736

β-Secretase Inhibitor II	Beta-secretase	Neurological Disease
β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC₅₀=700 nM for inhibition of total Aβ and IC₅₀=2.5 μM for Aβ_1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease .

HY-114950

EXP3179 Losartan Carboxaldehyde; DuP 167	COX	Cardiovascular Disease Inflammation/Immunology
EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions .

HY-147977

ALR1/2-IN-1	Aldose Reductase	Cancer
ALR1/2-IN-1 (Compound 6e) is an aldehyde reductase (ALR1) and aldose reductase (ALR2) inhibitor with IC₅₀ values of 3.26 μM and 3.06 μM against ALR1 and ALR2, respectively. ALR1/2-IN-1 shows anticancer activity .

HY-76006

3-Hydroxybenzaldehyde M-Hydroxybenzaldehyde	Aldehyde Dehydrogenase (ALDH)	Cardiovascular Disease
3-Hydroxybenzaldehyde is a precursor compound for phenolic compounds, such as Protocatechualdehyde (HY-N0295). 3-Hydroxybenzaldehyde is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo .

HY-13259

MG-132 Maximum Cited Publications 872 Publications Verification Z-Leu-Leu-Leu-al; MG132	Proteasome Autophagy Apoptosis	Cancer
MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC₅₀s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132, a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .

HY-126256

PRMT5-IN-1	Histone Methyltransferase	Cancer
PRMT5 IN-1, a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC₅₀ of 11 nM for PRMT5/MEP50. PRMT5 IN-1 can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions .

HY-126256A

PRMT5-IN-1 hydrochloride	Histone Methyltransferase	Cancer
PRMT5 IN-1 hydrochloride (compound 9), a hemiaminal, is a potent, selective protein arginine methyltransferase 5 (PRMT5) inhibitor with an IC₅₀ of 11 nM for PRMT5/MEP50. PRMT5 IN-1 hydrochloride can be converted to aldehydes and react with C449 to form covalent adducts under physiological conditions .

HY-D1603

BODIPY FL-EDA	Fluorescent Dye	Others
BODIPY FL-EDA is a fluorescent dye. BODIPY FL-EDA is an aliphatic-amine analog, and it can be coupled with aldehydes and ketones. BODIPY FL-EDA can be used for the detection of modified and normal deoxynucleotides and to determine DNA damage and genomic DNA methylation .

HY-131633A

(+)-JQ-1-aldehyde	Epigenetic Reader Domain	Cancer
(+)-JQ-1-aldehyde is the aldehyde form of (+)-JQ1. (+)-JQ-1-aldehyde can be uesd as a precursor to synthesize PROTACs, which targets BET bromodomains .

HY-135841

CM10	Aldehyde Dehydrogenase (ALDH)	Metabolic Disease Cancer
CM10 is a potent and selective aldehyde dehydrogenase 1A (ALDH1A) family inhibitor, with IC₅₀s of 1700, 740, and 640 nM for ALDH1A1, ALDH1A2, and ALDH1A3, respectively. CM10 does not inhibit any of the other ALDH family members. CM10 can regulate metabolism and has anti-cancer activity .

HY-P10007

Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Cancer
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (K_i = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC₅₀ = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .

HY-144075

JAK-IN-19	JAK	Inflammation/Immunology
JAK-IN-19 is a potent JAK inhibitor (PBMC IFNγ pIC₅₀=7.2 and HLF Eotaxin pIC₅₀=7.7). JAK-IN-19 has good retentive properties in the lung via mitigating being metabolized by Aldehyde Oxidase (AO), with diminished VEGFR2 selectivity (VEGFR2 pIC₅₀=7.0, Aurora B pIC₅₀=5.8) .

HY-W012570

Decyl aldehyde

Endogenous Metabolite Infection

Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

Decyl aldehyde	Endogenous Metabolite	Infection
Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

HY-114351

BODIPY FL hydrazide	Fluorescent Dye	Others
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λ_ex=495 nm, λ_em=516 nm) .

HY-124011

m-PEG3-aldehyde

PROTAC Linkers Cancer

m-PEG3-aldehyde is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
HY-140620

m-PEG4-aldehyde

PROTAC Linkers Cancer

m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-133456

Biotin-PEG2-aldehyde

PROTAC Linkers Cancer

Biotin-PEG2-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

m-PEG3-aldehyde	PROTAC Linkers	Cancer
m-PEG3-aldehyde is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

m-PEG4-aldehyde	PROTAC Linkers	Cancer
m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Biotin-PEG2-aldehyde	PROTAC Linkers	Cancer
Biotin-PEG2-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

HY-136074

Methyltetrazine-PEG4-aldehyde	ADC Linker	Cancer
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-136077

TCO-PEG3-aldehyde	ADC Linker	Cancer
TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-12465

Z-Ile-Leu-aldehyde 2 Publications Verification Z-IL-CHO; GSI-XII; γ-Secretase inhibitor XII	Notch γ-secretase Apoptosis	Cancer
Z-Ile-Leu-aldehyde (Z-IL-CHO) is a potent and competitive peptide aldehyde inhibitor of γ-secretase and notch .

HY-117041

m-PEG4-CH2-aldehyde

PROTAC Linkers Cancer

m-PEG4-CH2-aldehyde is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
HY-133457

Biotin-PEG2-C1-aldehyde

PROTAC Linkers Cancer

Biotin-PEG2-C1-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
HY-136051

Biotin-PEG3-aldehyde

ADC Linker Cancer

Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

m-PEG4-CH2-aldehyde	PROTAC Linkers	Cancer
m-PEG4-CH2-aldehyde is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

Biotin-PEG2-C1-aldehyde	PROTAC Linkers	Cancer
Biotin-PEG2-C1-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .

Biotin-PEG3-aldehyde	ADC Linker	Cancer
Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .

HY-136076

TCO-PEG3-CH2-aldehyde	ADC Linker	Cancer
TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-138518

Azido-PEG3-aldehyde	PROTAC Linkers	Cancer
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-112516

*Fmoc-Lys(amino aldehyde)-Boc*	Others	Others
Fmoc-Lys(amino aldehyde)-Boc is a lysine derivative, and is very sensitive to acid and heat. Fmoc-Lys(amino aldehyde)-Boc and can be used in solid phase synthesis .

HY-136054

N3-PEG5-aldehyde	ADC Linker	Cancer
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-146683

KS106	Aldehyde Dehydrogenase (ALDH) Apoptosis	Cancer
KS106 is a potent ALDH inhibitor with IC₅₀s of 334, 2137, 360 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS106 shows antiproliferative and anticancer effects with low low toxic.KS106 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS106 induces apoptosis and cell cycle arrest at the G2/M phase .

HY-146682

KS100	Aldehyde Dehydrogenase (ALDH) Apoptosis	Cancer
KS100 is a potent ALDH inhibitor with IC₅₀s of 230, 1542, 193 nM for ALDH1A1, ALDH2, and ALDH3A1, respectively. KS100 shows antiproliferative and anticancer effects with low low toxic. KS100 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS10600 induces apoptosis and cell cycle arrest at the G2/M phase .

Cat. No.	Product Name

HY-L021

Natural Product Library

4531 compounds

Natural products are small molecules produced naturally by any organism including primary and secondary metabolites. Natural sources may lead to basic research on potential bioactive components for commercial development as lead compounds in drug discovery.

Nature has been a source of medicinal agents for thousands of years, and an impressive number of modern drugs have been isolated from natural sources, many based on their use in traditional medicine. With the development of new molecular targets, there is an increasing demand for novel molecular diversity for screening. Natural products will play a crucial role in meeting this demand through the continued investigation of world’s bio-diversity, much of which remains unexplored.

MCE provides a unique collection of 4531 natural compounds that contain Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library is a useful tool for drug discovery that can be used for high throughput screening (HTS) and high content screening (HCS).

HY-L163

FDA-Approved Traditional Chinese Medicine Active Compound Library

320 compounds

Traditional Chinese medicine provides abundant natural resources for medicinal compounds, which are often considered effective and safe for drug discovery. Traditional Chinese medicine is based on the principle of "multiple components, multiple targets, and multiple pathways", and naturally has multiple pharmacological effects. As herbal medicine, the secondary plant metabolites in Chinese herbal medicine play an important role in alleviating many diseases in Traditional medicine and folk use. Therefore, the identification of traditional Chinese medicine derived compounds is also an important process in drug development and a necessary factor in dissecting the overall mechanism of action of traditional Chinese medicine. FDA listed compounds have completed extensive preclinical and clinical studies, exhibiting good biological activity, safety, and bioavailability.

MCE designs a unique collection of 320 FDA-approved traditional Chinese medicine active compounds, including flavonoids, polyphenols, alkaloids, terpenoids, and other structural types. It is a good tool for drug reuse and screening drugs from traditional Chinese medicine sources.

HY-L065

Traditional Chinese Medicine Active Compound Library

2845 compounds

Chinese herbal therapy is an important part of Traditional Chinese Medicine (TCM). It has been used for centuries in China, where herbs are considered fundamental therapy for many acute and chronic conditions. Many studies indicated TCM exerted an overall regulatory effect via multi-component and multi-target network. Active components from Traditional Chinese Medicine possess many medicinal properties such as antioxidant, anti-cancer, and anti-bacterial effects, which makes it an important source of new drugs. Nearly 200 modern medicines have been developed either directly or indirectly from the plants used as medicines in China. For example, artemisinin, used in multidrug resistant malaria, was first isolated from the Chinese herb Artemisia annua L. Today, scientists continue to identify compounds in Chinese herbal remedies that may be useful in the development of new therapeutic agents applicable in Western medicine.

MCE designs a unique collection of 2845 active compounds of Chinese Herbal Medicines. MCE Traditional Chinese Medicine Active Compound Library is a useful tool for discovery new drugs from TCM.

HY-L021P

Natural Product Library Plus

5315 compounds

MCE provides a unique collection of 5315 natural compounds that contains Saccharides and Glycosides, Phenylpropanoids, Quinones, Flavonoids, Terpenoids and Glycosides, Steroids, Alkaloid, Phenols, Acids and Aldehydes. Natural Product Library Plus, with more powerful screening capability, further complements Natural Product Library (HY-L021) by adding some compounds with low solubility or solution stability (Part B) to this library. All those supplementary are supplied in powder form.

Cat. No.	Product Name	Type

HY-137100

Cy 5 hydrazide Cyanine5 hydrazide	Fluorescent Dyes/Probes
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .

HY-151690

FAM hydrazide, 6-isomer	Fluorescent Dyes/Probes
FAM hydrazide, 6-isomer is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer can be used for the labeling of carbonyl compounds, aldehydes, and ketones .

HY-132264

FAM hydrazide, 6-isomer hydrochloride	Fluorescent Dyes/Probes
FAM hydrazide, 6-isomer hydrochloride is a hydrazide derivative of fluorescein (FAM). FAM is a xanthene dye, a parent of fluorescein dye series. FAM hydrazide, 6-isomer hydrochloride can be used for the labeling of carbonyl compounds, aldehydes, and ketones .

HY-D1882

Cy5.5 hydrazide

Fluorescent Dyes/Probes

Cy5.5 hydrazide is a fluorescent dye containing a hydrazide functionality. Cy5.5 hydrazide can be used to label aldehydes and ketones .

HY-D1667

BDP 558/568 hydrazide	Fluorescent Dyes/Probes
BDP 558/568 hydrazide is a carbonyl reactive hydrazide derivative of BDP 558/568 (BDP 558/568: Ex=558 nm, Em=568 nm). BDP 558/568 hydrazide can be used for the labeling of aldehydes or ketones.

HY-151774

TAMRA hydrazide (6-isomer)	Fluorescent Dyes/Probes
TAMRA hydrazide (6-isomer) is a click chemistry reagent that can be coupled to carbonyl compounds. The dye hydrazide in TAMRA hydrazide (6-isomer) labels carbonyl compounds such as aldehydes and ketones. TAMRA in TAMRA hydrazide (6-isomer) is a xanthene red fluorophore that reacts with terminal alkynes .

HY-D1604

BODIPY FL Ethylamine	Dyes
BODIPY FL Ethylamine is a fluorescent dye that reversibly reacts with aldehyde/ketone to yield a Schiff base. BODIPY FL Ethylamine can be reduced to form a stable amine derviative using sodium borohydride or sodium cyanoborohydride .

HY-D1603

BODIPY FL-EDA	Fluorescent Dyes/Probes
BODIPY FL-EDA is a fluorescent dye. BODIPY FL-EDA is an aliphatic-amine analog, and it can be coupled with aldehydes and ketones. BODIPY FL-EDA can be used for the detection of modified and normal deoxynucleotides and to determine DNA damage and genomic DNA methylation .

HY-114351

BODIPY FL hydrazide	Fluorescent Dyes/Probes
BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λ_ex=495 nm, λ_em=516 nm) .

HY-D1765

FM 1-43FX

Fluorescent Dyes/Probes

FM 1-43FX is a fluorescent membrane probe that contains an aliphatic amine which can react with aldehyde-based fixatives.

HY-D1970

ATTO 700 Cadaverin	Fluorescent Dyes/Probes
ATTO 700 Cadaverin is a cadaverine derivative of ATTO 700 for reactions of carboxylic acids, aldehydes and ketones with maximum excitation/emission wavelengths: 700/716 nm.

HY-D2055

ATTO 532 cadaverin	Fluorescent Dyes/Probes
ATTO 532 cadaverin is a cadaverine derivative of ATTO 532, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 532/552 nm.

HY-D2070

ATTO 680 cadaverin	Fluorescent Dyes/Probes
ATTO 680 cadaverin is a cadaverine derivative of ATTO 680, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 681/698 nm.

HY-D2039

ATTO 550 cadaverin	Fluorescent Dyes/Probes
ATTO 550 cadaverin is a cadaverine derivative of ATTO 550, used for carboxylic acid, aldehyde and ketone reactions, maximum excitation/emission wavelength: 554/576 nm.

HY-151644

Fluorescein hydrazide	Fluorescent Dyes/Probes
Fluorescein hydrazide is a colorimetric probe formed by the reaction of dihydrazine adipate with fluorescein isothiocyanate. Fluorescein hydrazide can be used to label aldehyde and ketone groups .

HY-128692

Lucifer Yellow CH dilithium salt

1 Publications Verification

Fluorescent Dyes/Probes

Lucifer Yellow CH dilithium salt is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .

HY-W127715

Lucifer Yellow CH dipotassium salt

1 Publications Verification

Fluorescent Dyes/Probes

Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively .

HY-D1757

Lucifer yellow ethylenediamine LYen; PAsp- LY	Fluorescent Dyes/Probes
Lucifer yellow ethylenediamine (LYen; PAsp- LY) is a polar tracer that can be coupled with aldehydes and ketones to form Schiff bases, which can be reduced to stable amine derivatives by sodium borohydride (NaBH4) or sodium cyanide borohydride (NaCNH3).

HY-114346A

BODIPY FL EDA free base

Dyes

ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.

HY-D1861

Sulfo-Cy3 hydrazide

Fluorescent Dyes/Probes

Sulfo-Cy3 hydrazide is a Cyanine 3 (Cy3) (HY-D0822) dye derivative with hydrazine functionality. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The hydrazide group of Sulfo-Cy3 hydrazide can form hydrazinone coupling with molecules containing aldehydes or ketones to form covalent bonds. Therefore, Cy3 azide plus can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

Cat. No.	Product Name	Type

HY-P2947

ALDH Aldehyde dehydrogenase (NAD(P))	Biochemical Assay Reagents
ALDH (Aldehyde dehydrogenase (NAD(P))) catalyzes the oxidation of aldehydes into their corresponding carboxylic acids with the concomitant reduction of the cofactor NAD(P) into NAD(P)H, is often used in biochemical studies. The ALDHs are one of many enzyme systems the body utilizes to alleviate aldehyde stress .

HY-W017425

N'-Phenylacetohydrazide Phenylhydrazine acetate	Biochemical Assay Reagents
N'-Phenylacetohydrazide consists of a phenyl group attached to the acetylhydrazide functional group via a hydrazine bond. This compound is commonly used as a reagent in organic chemistry for the determination of carbonyl compounds such as aldehydes and ketones.

HY-W142618

D-Glucal

Biochemical Assay Reagents

D-Glucal is an organic compound belonging to the family of aldoses, which are monosaccharides containing an aldehyde functional group. It has a six-carbon structure and is derived from glucose by oxidation of the primary alcohol group at carbon 1 to an aldehyde group. D-Glucal is a white crystalline solid that is soluble in water and has a sweet taste. It is an important intermediate in the chemical synthesis of a wide variety of compounds, including pharmaceuticals, agrochemicals, and natural products. D-Glucal can be converted into other carbohydrate derivatives such as glycosides, glycoconjugates and amino sugars. It also plays a role in the study of carbohydrate chemistry, where it is used as a chiral building block for the synthesis of complex structures.

HY-157916

ARP Aldehyde reactive probe	Biochemical Assay Reagents
ARP (Aldehyde reactive probe) is an aldehyde reactive probe for detecting abasic site (common DNA lesions and intermediates in mutagenesis and carcinogenesis) in DNA, which specificially tags AP site with biotin residues. ARP is highly sensitive with a femtomolar-level basic site detection capabilities (less than one site per 10 ⁴ nucleotides) .

HY-W760733

2,4-Decadienal	Biochemical Assay Reagents
2,4-Decadienal is a toxic aldehyde produced by the oxidation of linoleic acid-rich oils. 2,4-decadienal can be used as an alternative oxidation indicator for linoleic acid-rich oils .

HY-W018829

10-Undecenal Undecylenic Aldehyde	Biochemical Assay Reagents
10-Undecenal consists of an 11-carbon chain with a double bond between the 9th and 10th carbon atoms and an aldehyde group attached to the 1st carbon atom. This compound has a pungent or fatty smell and is commonly used as a flavoring commodity in foods such as bakery, confectionary and beverages.

HY-W008635

Tetrabutylammonium tetrahydroborate

Biochemical Assay Reagents

Tetrabutylammonium tetrahydroborate is an organic compound commonly used as a reducing agent and catalyst. It can act as a reducing agent in certain chemical reactions and can promote the reduction of organic compounds such as esters, aldehydes and ketones. In addition, this compound is also widely used in organic synthesis and chemical analysis, and also has important uses in some production processes.

HY-W074541

Girard’s reagent T

Trimethylacetohydrazideammonium chloride

Biochemical Assay Reagents

Girard's reagent T is often used in analytical chemistry as a derivatizing agent for carbonyl compounds. Girard's reagent T reacts with ketones and aldehydes to form stable hydrazones that can be readily analyzed by various techniques including chromatography and spectrophotometry. In addition, Girard's Reagent T has been used in the synthesis of a variety of organic compounds, including pharmaceuticals and agrochemicals.

HY-155887

DSPE-PEG-Amine, MW 3400 ammonium

DSPE-PEG-NH2, MW 3400 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 3400 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 3400 (ammonium) can be converted to aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155908

DSPE-PEG-Amine, MW 10000 ammonium

DSPE-PEG-NH2, MW 10000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 10000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 10000 (ammonium) can be converted into aromatic aldehydes by reacting with acetone-protected aromatic hydrazines on the surface of bovine carbonic anhydrase (BCA) molecules. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-155907

DSPE-PEG-Amine, MW 5000 ammonium

DSPE-PEG-NH2, MW 5000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 5000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. DSPE-PEG-Amine, MW 5000 (ammonium) amino group can be converted to aromatic aldehydes that react with acetone-protected aromatic hydrazides on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes produce liposome-Bah-BCA conjugates by forming diaryl hydrazone (BAH) with target enzyme molecules. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

HY-W440823A

DSPE-PEG-Amine, MW 1000 ammonium

DSPE-PEG-NH2, MW 1000 ammonium

Drug Delivery

DSPE-PEG-Amine, MW 1000 (ammonium) is a phosphoethanolamine involved in the synthesis of liposomes for delivery systems. The amino group of DSPE-PEG-Amine, MW 1000 (ammonium) can be converted to an aromatic aldehyde, which reacts with an acetone-protected aromatic hydrazine on the surface of the bovine carbonic anhydrase (BCA) molecule. Liposomes form a liposome-BAH-BCA conjugate by forming a bisarylhydrazone (BAH) with the target enzyme molecule. The conjugate catalyzes the hydration of carbon dioxide to bicarbonate.

Cat. No.	Product Name	Target	Research Area

HY-P4251

Gly-Phe-Gly-Aldehyde semicarbazone

Peptides Others

Gly-Phe-Gly-Aldehyde semicarbazone is a peptide.

HY-P4308

*Z-Pro-Pro-aldehyde-dimethyl acetal*	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-P4487

H-Pro-Pro-Asp-NH2	Peptides	Others
H-Pro-Pro-Asp-NH2 is a potent and selective catalyst for asymmetric aldol reactions. H-Pro-Pro-Asp-NH2 catalyzes aldol reactions between acetone and several aldehydes .

HY-P10007

Z-Gly-Pro-Phe-Leu-CHO Z-GPFL-CHO	Proteasome	Cancer
Z-Gly-Pro-Phe-Leu-CHO (Z-GPFL-CHO) is a tetrapeptide aldehyde that acts as a highly selective and potent proteasomal inhibitor (K_i = 1.5 µM for branched chain amino acid preferring, 2.3 µM for small neutral amino acid preferring, and 40.5 µM for chymotrypsin-like activities; IC₅₀ = 3.1 µM for peptidyl-glutamyl peptide hydrolyzing activity) .

HY-P4532

Ac-Leu-Val-Lys-Aldehyde	Cathepsin	Neurological Disease
Ac-Leu-Val-Lys-Aldehyde is a potent cathepsin B inhibitor with IC₅₀s of 4 nM. Ac-Leu-Val-Lys-Aldehyde significantly reduces quinolinic acid (HY-100807)-induced striatal cell death and causes accumulation of LC3-II .

HY-P4535

Ac-Trp-Glu-His-Asp-Aldehyde

Caspase Inflammation/Immunology

Ac-Trp-Glu-His-Asp-Aldehyde is a potent and selective caspase-1 inhibitor with a K_i value of 56 pM .

HY-P3761

Ac-Tyr-Val-Lys-Asp-aldehyde	Caspase	Others
Ac-Tyr-Val-Lys-Asp-aldehyde is a caspase-1 inhibitor, can be used for disease research including anemia-associated to chronic diseases, chemotherapy-induced anemia and Diamond-Blackfan anemia .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N8016

Nonanal	other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields Inflammation/Immunology	Others
Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity .

HY-W004305

Hexadecanal Palmitaldehyde	Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals .

HY-76006

3-Hydroxybenzaldehyde M-Hydroxybenzaldehyde	Cardiovascular Disease Structural Classification Monophenols other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Phenols Plants Disease Research Fields	Aldehyde Dehydrogenase (ALDH)
3-Hydroxybenzaldehyde is a precursor compound for phenolic compounds, such as Protocatechualdehyde (HY-N0295). 3-Hydroxybenzaldehyde is a substrate of aldehyde dehydrogenase (ALDH) in rats and humans (ALDH2). 3-Hydroxybenzaldehyde has vasculoprotective effects in vitro and in vivo .

HY-W012570

Decyl aldehyde	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Decyl aldehyde is a simple ten-carbon aldehyde. Decyl aldehyde is a bacterial luciferase substrate.

HY-N8896

Ursolic aldehyde	Triterpenes Structural Classification Terpenoids Source classification Plants Bignoniaceae Campsis grandiflora (Thunb.) Schum.	Others
Ursolic aldehyde is a triterpenoid isolated from plants .

HY-79494

Glyoxalic acid 1 Publications Verification NSC 27785; Formylformic acid; Oxalaldehydic acid	Structural Classification Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Disease markers Other Diseases Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Glyoxalic acid (NSC 27785) is an organic compound that is both an aldehyde and a carboxylic acid.

HY-N12240

Oleanolic aldehyde	Triterpenes Structural Classification Terpenoids Source classification Vitis vinifera cv. Zalema Plants Vitaceae	Bacterial
Oleanolic aldehyde is an antimicrobial compound used to inhibit oral bacteria. Oleanolic aldehyde inhibits Streptococcus mutans and Porphyromonas gingivalis, which are associated with dental caries and periodontal disease, with minimum inhibitory concentrations (MICs) of 488 μg/mL and 250 μg/mL, respectively .

HY-W020014

Pyruvic aldehyde	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Disease markers Endocrine diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Pyruvic aldehyde is often used as a reagent in organic synthesis, as a flavoring agent, and in tanning.

HY-W004307

Octadecanal	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Octadecanal is a long-chain aldehyde, present in both thigh and breast muscle .

HY-W008393

(-)-Corey lactone diol	Classification of Application Fields Other Diseases Disease Research Fields	Others
(-)-Corey lactone diol is a reduced version of corey aldehyde. A building block in the chemical synthesis.

HY-I0637

Isovanillin 3-Hydroxy-4-methoxybenzaldehyde	Monophenols Ketones, Aldehydes, Acids Source classification Asclepiadaceae Phenols Plants Periploca sepium Bunge	Others
Isovanillin is an aldehyde oxidase inhibitor . Antispasmodic activities . Antidiarrheal activities .

HY-N8015

Octanal	Infection other families Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Source classification Plants Disease Research Fields	Bacterial Endogenous Metabolite
Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells .

HY-76224

3-Furaldehyde	Classification of Application Fields Ketones, Aldehydes, Acids Source classification Other Diseases Endogenous metabolite Disease Research Fields	Others
3-Furaldehyde is a member of furans and an aldehyde, and can be used to synthesize the neoclerodane diterpene Salvinorin A .

HY-N2597

Prunetin	Structural Classification Classification of Application Fields Source classification Plants Trifolium pratense Linn. Flavonoids Leguminosae Phenols Polyphenols Inflammation/Immunology Disease Research Fields Glycyrrhiza uralensis Fisch. Isoflavones	Aldehyde Dehydrogenase (ALDH)
Prunetin, an O-methylated isoflavone, possesses anti-inflammatory activity. Prunetin is a potent human aldehyde dehydrogenases inhibitor .

HY-N3616

trans-Coniferyl aldehyde	Structural Classification Monophenols Simple Phenylpropanols Source classification Phenols Myrtaceae Syzygium aromaticum (L.) Merr. & L.M.Perry Phenylpropanoids Plants	DNA/RNA Synthesis Endogenous Metabolite
trans-Coniferyl aldehyde (compound 2) is a natural compound isolated from the buds of clove (Syzygium aromaticum).trans-Coniferyl aldehyde suppresses 63% of the UV mutable gene expression at 1.20 μM, and with an ID₅₀ value of 0.76 μM,and has the antimutagenic activities against furylfuramide, Trp-P-1, and activated Trp-P-1 .

HY-125443

Lucialdehyde A	Triterpenes Structural Classification Microorganisms Terpenoids Source classification	Others
Lucialdehydes A is a lanostante-type triterpene aldehydes, isolated from the fruiting bodies of Ganoderma lucidum. Lucialdehydes A shows cytotoxic effects on tumor cells, including Lewis lung carcinoma (LLC), T-47D, Sarcoma 180, and Meth-A tumor cell lines .

HY-N3149

(E)-2-Hydroxycinnamaldehyde	Structural Classification Monophenols Cinnamomum cassia (L.) D. Don Source classification Phenols Plants Lauraceae	STAT Apoptosis Reactive Oxygen Species
(E)-2-Hydroxycinnamaldehyde is an aldehyde that can be separated from the stem bark of cinnamon. (E)-2-Hydroxycinnamaldehyde inhibits cell proliferation and induces apoptosis by inhibiting signal transduction of STAT3 and reactive oxygen species production. (E)-2-Hydroxycinnamaldehyde has antitumor activity .

Cat. No.	Product Name	Chemical Structure

HY-N8015S

Octanal-d16
Octanal-d₁₆ is the deuterium labeled Octanal[1]. Octanal is an aromatic aldehyde, with antioxidant and antimicrobial activities. Octanal shows cytotoxicity against Hela cells[2].

HY-N8016S

Nonanal-d18

Nonanal-d₁₈ is the deuterium labeled Nonanal[1]. Nonanal is a saturated fatty aldehyde with antidiarrhoeal activity[2].
HY-I0637S

Isovanillin-d3

Isovanillin-d₃ is the deuterium labeled Isovanillin[1]. Isovanillin is an aldehyde oxidase inhibitor[2]. Antispasmodic activities[3]. Antidiarrheal activities[4].

HY-50683S

JNJ-38877605-d1
JNJ-38877605-d1 (compound DO-2) is a highly selective MNNG HOS transforming (MET) inhibitor. JNJ-38877605-d1 is thought to diminish the formation of the Aldehyde Oxidase 1 inactive metabolite M3 .

HY-W001187S

Tempo-d18
Tempo-d₁₈ is the deuterium labeled Tempo[1]. Tempo is a classic nitroxide radical and is a selective scavenger of ROS that dismutases superoxide in the catalytic cycle. Tempo induces DNA-strand breakage. Tempo can be used as an organocatalyst for the oxidation of primary alcohols to aldehydes. Tempo has mutagenic and antioxidant effects[2][3][4][5].

Cat. No.	Product Name		Classification

HY-138518

Azido-PEG3-aldehyde		PROTAC Synthesis Azide
Azido-PEG3-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG3-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-136074

Methyltetrazine-PEG4-aldehyde		Tetrazine ADC Synthesis
Methyltetrazine-PEG4-aldehyde is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-PEG4-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

HY-136077

TCO-PEG3-aldehyde		TCO ADC Synthesis
TCO-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-136076

TCO-PEG3-CH2-aldehyde		ADC Synthesis TCO
TCO-PEG3-CH2-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . TCO-PEG3-CH2-aldehyde is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

HY-136054

N3-PEG5-aldehyde		ADC Synthesis Azide
N3-PEG5-aldehyde is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . N3-PEG5-aldehyde is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

HY-135977

DBCO-SS-aldehyde		DBCO ADC Synthesis
DBCO-SS-aldehyde is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-SS-aldehyde is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

HY-136140

Aldehyde-benzyl-PEG5-alkyne		Alkynes PROTAC Synthesis
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Aldehyde-benzyl-PEG5-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-133465

Tetrazine-Ph-PEG4-Ph-aldehyde		Tetrazine PROTAC Synthesis
Tetrazine-Ph-PEG4-Ph-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Tetrazine-Ph-PEG4-Ph-aldehyde is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.

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aldehydes

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