Luc Yellow CH dilithium
Based on 7 publication(s) in Google Scholar
Luc Yellow CH dilithium is a high-intensity fluorescent probe containing free hydrazyl groups. Luc Yellow CH can react with fatty aldehydes at room temperature. Luc Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Luc Yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively.
For research use only. We do not sell to patients.
- Purity: 99.2%
- CAS No.: 67769-47-5
- Formula: C13H9Li2N5O9S2
- Molecular Weight:457.25
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Luc Yellow CH dilithium
More- ACS Nano. 2026 Apr 14;20(14):10889-10904. [Abstract]
- Mater Today Bio. 2025 Mar 18:32:101677. [Abstract]
- Free Radic Biol Med. 2022 Jan:178:271-294. [Abstract]
- Fluids Barriers CNS. 2026 Apr 10;23(1):57. [Abstract]
- RSC Pharm. 2025 Jul 18. [Abstract]
- Sci Rep. 2025 Oct 6;15(1):34716. [Abstract]
- Biochem Biophys Res Commun. 2025 Sep 30:782:152552. [Abstract]
Customer Validation & Images
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Others
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Cell Imaging/Staining
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Cell Imaging/Staining
Biological Activity
Guide (The following is our recommended protocol. This protocol is only a guide and should be modified according to your specific needs).
1 Preparation of dye working solution [3]
1) Prepare 0.33 M lithium citrate solution containing 5% Lucifer Yellow CH as the working solution.
2 Specific staining steps
1) Insert a glass capillary microelectrode containing Lucifer Yellow CH working solution into the neuron and apply a constant hyperpolarizing current (0.2-0.5 nA) for 5-15 min for ion electrophoresis injection.
2) Simultaneously monitor the DC potential and action potential induced by intracellular stimulation. Only one cell is labeled per slice.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 67769-47-5
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Appearance Solid
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Molecular Weight 457.25
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Formula C13H9Li2N5O9S2
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Color Yellow to orange
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SMILES
O=S(C1=C(N)C2=CC(S(=O)(O[Li])=O)=CC(C(N(NC(NN)=O)C3=O)=O)=C2C3=C1)(O[Li])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (7)
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Journal Impact Factor
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Most Recent
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ACS Nano
Atorvastatin-Driven Methuosis in Glioblastoma: A Biomimetic Nanodrug for Targeted Tumor Therapy. [Abstract]2026 Apr 14;20(14):10889-10904. PMID: 41933442 -
Mater Today Bio
Porcine pericardium crosslinked with POSS-PEG-CHO possesses weakened immunogenicity and anti-calcification property. [Abstract]2025 Mar 18:32:101677. PMID: 40242484
Luc Yellow CH dilithium purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Mar 18:32:101677. [Abstract]
Lucifer yellow CH (10 μg/mL; 12 h) staining images of DPP, GLUT-PP and POSS-PEG-PP.
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Free Radic Biol Med
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury. [Abstract]2022 Jan:178:271-294. PMID: 34883251 -
Fluids Barriers CNS
Novel paracellular marker based on ᴅ-dipeptide structure for highly sensitive quantification with UPLC-MS/MS for in vitro and in vivo blood-brain barrier permeability analysis. [Abstract]2026 Apr 10;23(1):57. PMID: 41964022 -
RSC Pharm
Systematic screening of excipients to stabilize aerosolized lipid nanoparticles for enhanced mRNA delivery. [Abstract]2025 Jul 18. PMID: 40689160 -
Sci Rep
Disrupting the interaction between connexin 43 and calmodulin restores gap junction function and mitigates reperfusion arrhythmias. [Abstract]2025 Oct 6;15(1):34716. PMID: 41053105
Luc Yellow CH dilithium purchased from MedChemExpress. Usage Cited in: Sci Rep. 2025 Oct 6;15(1):34716. [Abstract]
The H9c2 cells were treated in normoxia and hypoxia for the indicated times, and the distance of LY dye (Luc Yellow CH dilithium: 1mg/mL; 5 min) spread was measured to evaluate the GJ functionality.
Luc Yellow CH dilithium purchased from MedChemExpress. Usage Cited in: Sci Rep. 2025 Oct 6;15(1):34716. [Abstract]
The H/R-treated H9c2 cells were cultured in a culture medium containing SP15 (50 µM) for 24 h, and the distance of LY dye (Luc Yellow CH dilithium: 1mg/mL; 5 min) spread was measured to evaluate the GJ functionality.
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Biochem Biophys Res Commun
Sevoflurane preconditioning improves Cx43 localization and electrical conduction by stabilizing myocardial microtubule structure during ischemia-reperfusion. [Abstract]2025 Sep 30:782:152552. PMID: 40902546
Solvent & Solubility
H2O : 25 mg/mL (54.67 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Stewart WW. Functional connections between cells as revealed by dye-coupling with a highly fluorescent naphthalimide tracer. Cell. 1978 Jul;14(3):741-59. [Content Brief]
[2]. Klein M, et al. Transport of lucifer yellow CH into plant vacuoles--evidence for direct energization of a sulphonatedsubstance and implications for the design of new molecular probes. FEBS Lett. 1997 Dec 22;420(1):86-92. [Content Brief]
[3]. Kawata M, et al. Immunohistochemical identification of Lucifer Yellow-labeled neurons in the rat supraoptic nucleus. Histochemistry. 1983;78(1):21-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.1870 mL | 10.9349 mL | 21.8699 mL | 54.6747 mL |
| 5 mM | 0.4374 mL | 2.1870 mL | 4.3740 mL | 10.9349 mL | |
| 10 mM | 0.2187 mL | 1.0935 mL | 2.1870 mL | 5.4675 mL | |
| 15 mM | 0.1458 mL | 0.7290 mL | 1.4580 mL | 3.6450 mL | |
| 20 mM | 0.1093 mL | 0.5467 mL | 1.0935 mL | 2.7337 mL | |
| 25 mM | 0.0875 mL | 0.4374 mL | 0.8748 mL | 2.1870 mL | |
| 30 mM | 0.0729 mL | 0.3645 mL | 0.7290 mL | 1.8225 mL | |
| 40 mM | 0.0547 mL | 0.2734 mL | 0.5467 mL | 1.3669 mL | |
| 50 mM | 0.0437 mL | 0.2187 mL | 0.4374 mL | 1.0935 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Luc Yellow CH dilithium Related Classifications
HY-128692 Related Classifications
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