Lucifer Yellow CH dipotassium salt
Based on 7 publication(s) in Google Scholar
Lucifer Yellow CH dipotassium is a high-intensity fluorescent probe containing free hydrazyl groups. Lucifer Yellow CH can react with fatty aldehydes at room temperature. Lucifer Yellow CH serves as a biological tracer to monitor neuronal branching, regeneration, gap junction detection and characterization, and selective ablation of cells after aldehyde fixation. Lucifer yellow CH displays the maximum excitation/emission of 430 nm/540 nm, respectively.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 71206-95-6
- Formula: C13H9K2N5O9S2
- Molecular Weight:521.57
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Lucifer Yellow CH dipotassium salt
More- ACS Nano. 2026 Apr 14;20(14):10889-10904. [Abstract]
- Mater Today Bio. 2025 Mar 18:32:101677. [Abstract]
- Free Radic Biol Med. 2022 Jan:178:271-294. [Abstract]
- Fluids Barriers CNS. 2026 Apr 10;23(1):57. [Abstract]
- RSC Pharm. 2025 Jul 18. [Abstract]
- Sci Rep. 2025 Oct 6;15(1):34716. [Abstract]
- Biochem Biophys Res Commun. 2025 Sep 30:782:152552. [Abstract]
Customer Validation & Images
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Others
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Cell Imaging/Staining
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Cell Imaging/Staining
Biological Activity
Guidelines (Following is our recommended protocol. This protocol only provides a guideline, and should be modified according to your specific needs).
When Lucifer Yellow CH dipotassium salt is used in neuronal tracing experiments, microinjection is recommended[3].
Note:1. It is recommended to store the stock solution at -20°C or -80°C away from light and avoid repetitive freeze-thaw cycles.
2. Please adjust the concentration of Lucifer Yellow CH (dipotassium salt) working solution according to the actual situation.
3. This product is for R&D use only, not for drug, household, or other uses.
4. For your safety and health, please wear a lab coat and disposable gloves to operate.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 71206-95-6
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Appearance Solid
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Molecular Weight 521.57
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Formula C13H9K2N5O9S2
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Color Yellow to orange
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SMILES
O=C(NN1C(C2=CC(S(=O)(O[K])=O)=CC3=C(C(S(=O)(O[K])=O)=CC(C1=O)=C23)N)=O)NN
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (7)
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Journal Impact Factor
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Most Recent
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ACS Nano
Atorvastatin-Driven Methuosis in Glioblastoma: A Biomimetic Nanodrug for Targeted Tumor Therapy. [Abstract]2026 Apr 14;20(14):10889-10904. PMID: 41933442 -
Mater Today Bio
Porcine pericardium crosslinked with POSS-PEG-CHO possesses weakened immunogenicity and anti-calcification property. [Abstract]2025 Mar 18:32:101677. PMID: 40242484
Lucifer Yellow CH dipotassium salt purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Mar 18:32:101677. [Abstract]
Lucifer yellow CH (10 μg/mL; 12 h) staining images of DPP, GLUT-PP and POSS-PEG-PP.
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Free Radic Biol Med
A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of traumatic brain injury. [Abstract]2022 Jan:178:271-294. PMID: 34883251 -
Fluids Barriers CNS
Novel paracellular marker based on ᴅ-dipeptide structure for highly sensitive quantification with UPLC-MS/MS for in vitro and in vivo blood-brain barrier permeability analysis. [Abstract]2026 Apr 10;23(1):57. PMID: 41964022 -
RSC Pharm
Systematic screening of excipients to stabilize aerosolized lipid nanoparticles for enhanced mRNA delivery. [Abstract]2025 Jul 18. PMID: 40689160 -
Sci Rep
Disrupting the interaction between connexin 43 and calmodulin restores gap junction function and mitigates reperfusion arrhythmias. [Abstract]2025 Oct 6;15(1):34716. PMID: 41053105
Lucifer Yellow CH dipotassium salt purchased from MedChemExpress. Usage Cited in: Sci Rep. 2025 Oct 6;15(1):34716. [Abstract]
The H9c2 cells were treated in normoxia and hypoxia for the indicated times, and the distance of LY dye (Luc Yellow CH dilithium: 1mg/mL; 5 min) spread was measured to evaluate the GJ functionality.
Lucifer Yellow CH dipotassium salt purchased from MedChemExpress. Usage Cited in: Sci Rep. 2025 Oct 6;15(1):34716. [Abstract]
The H/R-treated H9c2 cells were cultured in a culture medium containing SP15 (50 µM) for 24 h, and the distance of LY dye (Luc Yellow CH dilithium: 1mg/mL; 5 min) spread was measured to evaluate the GJ functionality.
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Biochem Biophys Res Commun
Sevoflurane preconditioning improves Cx43 localization and electrical conduction by stabilizing myocardial microtubule structure during ischemia-reperfusion. [Abstract]2025 Sep 30:782:152552. PMID: 40902546
Solvent & Solubility
DMSO : 83.33 mg/mL (159.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 5 mg/mL (9.59 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (283 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 1.9173 mL | 9.5864 mL | 19.1729 mL | 47.9322 mL |
| 5 mM | 0.3835 mL | 1.9173 mL | 3.8346 mL | 9.5864 mL | |
| DMSO | 10 mM | 0.1917 mL | 0.9586 mL | 1.9173 mL | 4.7932 mL |
| 15 mM | 0.1278 mL | 0.6391 mL | 1.2782 mL | 3.1955 mL | |
| 20 mM | 0.0959 mL | 0.4793 mL | 0.9586 mL | 2.3966 mL | |
| 25 mM | 0.0767 mL | 0.3835 mL | 0.7669 mL | 1.9173 mL | |
| 30 mM | 0.0639 mL | 0.3195 mL | 0.6391 mL | 1.5977 mL | |
| 40 mM | 0.0479 mL | 0.2397 mL | 0.4793 mL | 1.1983 mL | |
| 50 mM | 0.0383 mL | 0.1917 mL | 0.3835 mL | 0.9586 mL | |
| 60 mM | 0.0320 mL | 0.1598 mL | 0.3195 mL | 0.7989 mL | |
| 80 mM | 0.0240 mL | 0.1198 mL | 0.2397 mL | 0.5992 mL | |
| 100 mM | 0.0192 mL | 0.0959 mL | 0.1917 mL | 0.4793 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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