JAK-IN-19
JAK-IN-19 is a potent JAK inhibitor (PBMC IFNγ pIC50=7.2 and HLF Eotaxin pIC50=7.7). JAK-IN-19 has good retentive properties in the lung via mitigating being metabolized by Aldehyde Oxidase (AO), with diminished VEGFR2 selectivity (VEGFR2 pIC50=7.0, Aurora B pIC50=5.8).
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- No. CAS: 3035893-19-4
- Fòrmula: C26H36FN5O2
- Peso molecular:469.59
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 3035893-19-4
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Peso molecular 469.59
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Fòrmula C26H36FN5O2
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SMILES
CCC1=CC(O)=C(C=C1C2=CC3=C(C(N[C@H](CO)C)=C2)N=C(N=C3)NCCCCCN(C)C)F
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JAK-IN-19 Related Classifications
HY-144075 Related Classifications
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