1. Metabolic Enzyme/Protease
  2. Prolyl Endopeptidase (PREP)
  3. Z-Pro-Pro-aldehyde-dimethyl acetal

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease.

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Custom Peptide Synthesis

Z-Pro-Pro-aldehyde-dimethyl acetal Chemical Structure

Z-Pro-Pro-aldehyde-dimethyl acetal Chemical Structure

CAS No. : 170116-63-9

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Description

Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC50= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease[1][2].

IC50 & Target

PREP

12 nM (IC50)

Molecular Weight

376.45

Formula

C20H28N2O5

CAS No.
Sequence

Pro-{Pro-Aldehyde-dimethyl acetal}

Sequence Shortening

P-{Pro-Aldehyde-dimethyl acetal}

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Z-Pro-Pro-aldehyde-dimethyl acetal Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Z-Pro-Pro-aldehyde-dimethyl acetal
Cat. No.:
HY-P4308
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