Biotin-PEG3-aldehyde
Based on 1 Customer Validation
Biotin-PEG3-aldehyde is a cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Purity : 95.0%
- CAS No.: 889443-90-7
- Formula: C26H38N4O7S
- Molecular Weight:550.67
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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Cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 889443-90-7
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Appearance Solid
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Molecular Weight 550.67
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Formula C26H38N4O7S
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Color Off-white to light yellow
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SMILES
O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(NCCOCCOCCOCCNC(C3=CC=C(C([H])=O)C=C3)=O)=O)N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 200 mg/mL (363.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 200 mg/mL (363.19 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.8160 mL | 9.0798 mL | 18.1597 mL | 45.3992 mL |
| 5 mM | 0.3632 mL | 1.8160 mL | 3.6319 mL | 9.0798 mL | |
| 10 mM | 0.1816 mL | 0.9080 mL | 1.8160 mL | 4.5399 mL | |
| 15 mM | 0.1211 mL | 0.6053 mL | 1.2106 mL | 3.0266 mL | |
| 20 mM | 0.0908 mL | 0.4540 mL | 0.9080 mL | 2.2700 mL | |
| 25 mM | 0.0726 mL | 0.3632 mL | 0.7264 mL | 1.8160 mL | |
| 30 mM | 0.0605 mL | 0.3027 mL | 0.6053 mL | 1.5133 mL | |
| 40 mM | 0.0454 mL | 0.2270 mL | 0.4540 mL | 1.1350 mL | |
| 50 mM | 0.0363 mL | 0.1816 mL | 0.3632 mL | 0.9080 mL | |
| 60 mM | 0.0303 mL | 0.1513 mL | 0.3027 mL | 0.7567 mL | |
| 80 mM | 0.0227 mL | 0.1135 mL | 0.2270 mL | 0.5675 mL | |
| 100 mM | 0.0182 mL | 0.0908 mL | 0.1816 mL | 0.4540 mL |
Biotin-PEG3-aldehyde Related Classifications
HY-136051 Related Classifications
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