3-Furaldehyde
Based on 1 Customer Validation
3-Furaldehyde is a member of furans and an aldehyde, and can be used to synthesize the neoclerodane diterpene Salvinorin A.
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- Reinheit : 99.98%
- CAS. Nr.: 498-60-2
- Formel: C5H4O2
- Molecular Weight:96.08
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Speicherung:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-W015912
2-AcetylfuranIntermediate In Foods -
HY-21075
3-Furanoic acidEndogenous Metabolite -
HY-W012946
2-Furoic acid -
HY-W011664
1,3-DiphenylisobenzofuranFluorochrome -
HY-W002105
2,5-Furandicarboxylic acidEndogenous Metabolite -
HY-W015912R
2-Acetylfuran (Standard) -
HY-21075R
3-Furanoic acid (Standard)Endogenous Metabolite -
HY-Z0059
Sacubitrilat impurity 32Drug Impurity -
HY-W012946R
2-Furoic acid (Standard) -
HY-W002105R
2,5-Furandicarboxylic acid (Standard)Standard of 2,5-Furandicarboxylic acid -
HY-DY1053
1,3-Diphenylisobenzofuran (solution)Fluorochrome -
HY-Z0059R
Sacubitrilat impurity 32 (Standard)
Biologische Aktivität
Beschreibung
In Vitro
3-Furaldehyde is an atmospheric pollutant, mainly derived from biomass burning[1].
3-Furaldehyde undergos photoisomerization reaction, that converts the trans isomer into the cis isomer and reach a photochemical equilibrium state under ultraviolet light[1].
3-Furaldehyde also undergos photolysis reaction, that undergo decarbonylation reaction to produce products such as furan, cyclopropene and acrylene under higher energy ultraviolet light[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS. Nr. 498-60-2
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Appearance Liquid (Density: 1.111 g/cm3)
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Molecular Weight 96.08
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Formel C5H4O2
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Color Colorless to light yellow
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SMILES
O=CC1=COC=C1
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (1040.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (52.04 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 5 mg/mL (52.04 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Reinheit & Dokumentation
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Data Sheet (278 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Nihal Kuş, et al. Photoisomerization and photochemistry of matrix-isolated 3-furaldehyde. J Phys Chem A. 2010 Dec 2;114(47):12427-36. [Content Brief]
[2]. Yuzhou Wang, et al. Total Synthesis of the Neoclerodane Diterpene Salvinorin A via an Intramolecular Diels-Alder Strategy. Org Lett. 2018 Jun 1;20(11):3418-3421. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.4080 mL | 52.0400 mL | 104.0799 mL | 260.1998 mL |
| 5 mM | 2.0816 mL | 10.4080 mL | 20.8160 mL | 52.0400 mL | |
| 10 mM | 1.0408 mL | 5.2040 mL | 10.4080 mL | 26.0200 mL | |
| 15 mM | 0.6939 mL | 3.4693 mL | 6.9387 mL | 17.3467 mL | |
| 20 mM | 0.5204 mL | 2.6020 mL | 5.2040 mL | 13.0100 mL | |
| 25 mM | 0.4163 mL | 2.0816 mL | 4.1632 mL | 10.4080 mL | |
| 30 mM | 0.3469 mL | 1.7347 mL | 3.4693 mL | 8.6733 mL | |
| 40 mM | 0.2602 mL | 1.3010 mL | 2.6020 mL | 6.5050 mL | |
| 50 mM | 0.2082 mL | 1.0408 mL | 2.0816 mL | 5.2040 mL | |
| 60 mM | 0.1735 mL | 0.8673 mL | 1.7347 mL | 4.3367 mL | |
| 80 mM | 0.1301 mL | 0.6505 mL | 1.3010 mL | 3.2525 mL | |
| 100 mM | 0.1041 mL | 0.5204 mL | 1.0408 mL | 2.6020 mL |
3-Furaldehyde Related Classifications
HY-76224 Related Classifications
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