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2'-FL

" in MedChemExpress (MCE) Product Catalog:

80

Inhibitors & Agonists

30

Fluorescent Dye

2

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2

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2

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2

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17

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3

Isotope-Labeled Compounds

3

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1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N9965

    2'-FL

    TNF Receptor Interleukin Related Infection Inflammation/Immunology
    2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines .
    2'-Fucosyllactose
  • HY-110210

    BODIPY FL,SE

    Fluorescent Dye Others
    BODIPY-FL NHS ester (BODIPY FL, SE) is an amine-reactive fluorescent probe. The maximum excitation/emission values are 502/511 nm. BODIPY-FL NHS ester can be used to synthesize protease substrates .
    BODIPY-<em>FL</em> NHS ester
  • HY-156856

    ADC Cytotoxin Cancer
    FL118-14-Propanol is a FL118 derivative. FL118-14-Propanol synthesized ADC molecule has good anti-tumor effect in mice .
    <em>FL</em>118-14-Propanol
  • HY-120115

    Olaparib-bodipy FL

    PARP Cancer
    PARPi-FL is a small molecule and fluorescent inhibitor of PARP1. PARPi-FL is a highly selective probe and can be used as an imaging agent to detect glioblastomas in vivo .
    PARPi-<em>FL</em>
  • HY-157419

    7-(4-Ethylphenyl)-FL118

    Apoptosis Cancer
    FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, <6.4 nM, 28.5 nM and <6.4 nM in HCT116, HepG2, MCF-7, A549 and HeLa cells, respectively. FL77-24 mainly causes cell cycle arrest in S and G2/M phases .
    <em>FL</em>77-24
  • HY-114354

    BOD FL alkyne

    Fluorescent Dye Others
    BODIPY FL alkyne (BOD FL alkyne) is a green-fluorescent dye (Ex=503 nm; Em=512 nm), a bright and photostable fluorophore which emits in fluorescein (FAM) channel. BODIPY FL alkyne can be conjugated with a number of azide-containing molecules by copper-catalyzed Click Chemistry.
    BODIPY <em>FL</em> alkyne
  • HY-B0810

    FL-1039

    Bacterial Antibiotic Infection
    Pivmecillinam (FL-1039) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
    Pivmecillinam
  • HY-B0810A

    FL-1039 hydrochloride

    Bacterial Antibiotic Infection
    Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic.
    Pivmecillinam hydrochloride
  • HY-160256

    Liposome Fluorescent Dye Others
    DSPE-PEG-BDP FL,MW 2000 is a PEG lipid, composed of a DSPE phospholipid and a BDP FL dye .
    DSPE-PEG-BDP <em>FL</em>,MW 2000
  • HY-D1368

    Fluorescent Dye Others
    BDP FL amine hydrochloride is a borondipyrromethene dye with good water solubility. BDP FL amine hydrochloride can be read on the FAM channel .
    BDP <em>FL</em> amine hydrochloride
  • HY-D1603

    Fluorescent Dye Others
    BODIPY FL-EDA is a fluorescent dye. BODIPY FL-EDA is an aliphatic-amine analog, and it can be coupled with aldehydes and ketones. BODIPY FL-EDA can be used for the detection of modified and normal deoxynucleotides and to determine DNA damage and genomic DNA methylation .
    BODIPY <em>FL</em>-EDA
  • HY-D2255

    Fluorescent Dye Others
    BDP FL ceramide, a highly fluorescent lipid, is a conjugate of green-emitting BDP FL fluorophore with sphingosine. BDP FL ceramide can be used for the visualization of the Golgi apparatus via fluorescence microscopy.The excitation wavelength is 503 nm and the emission wavelength is 509 nm .
    BDP <em>FL</em> ceramide
  • HY-43520

    Fluorescent Dye Others
    BODIPY-FL is a potent fluorescent dye. BODIPY-FL can be used to label probe or primer for fluorescent quenching-based quantitative detection of specific DNA/RNA.BODIPY-FL-labeled monoterpenoid can be used to examine the features of a broad spectrum of Gram-positive and Gram-negative bacteria and pathogenic fungi as well .
    BODIPY-<em>FL</em>
  • HY-D1718

    PROTAC Linkers Cancer
    BDP FL-PEG5-acid is a BDP FL acid linker containing a hydrophilic PEG spacer arm. BDP FL-PEG5-acid can be used in the synthesis of PROTACs. BDP FL is a green-fluorescent dye, and the hydrophilic PEG spacer arm increases water solubility and membrane permability.
    BDP <em>FL</em>-PEG5-acid
  • HY-D1608

    Calcium Channel Others
    BODIPY FL Thapsigargin is a potent green fluorescent dye. BODIPY FL Thapsigargin inhibits intracellular SERCA-type Ca2+ pumps present in the sarcoplasmic/endoplasmic reticulum. BODIPY FL Thapsigargin used for investigation of thapsigargin binding sites in live cells .
    BODIPY <em>FL</em> Thapsigargin
  • HY-114352

    Fluorescent Dye Others
    BODIPY FL-X is a green-fluorescent dye. BODIPY FL-X has the succinimidyl ester covalently coupled to proteins. BODIPY FL-X has high fluorescence quantum yield and is relatively insensitive to pH change. (λex=504 nm, λem=510 nm) .
    BODIPY <em>FL</em>-X
  • HY-D1506

    Fluorescent Dye Others
    Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    <em>Fl</em>-DIBO
  • HY-D1595

    Fluorescent Dye Others
    BODIPY FL Cholesterol is a green fluorescent, lipophilic probe. BODIPY FL Cholesterol can be used for the research of lipid transport processes and lipid-protein interactions .
    BODIPY <em>FL</em> Cholesterol
  • HY-D1610

    Fluorescent Dye Others
    BODIPY FL C5 is a green fluorescent fatty acid. BODIPY FL C5 can be used as a precursor for the synthesis of various fluorescent phospholipids. BODIPY FL C5 is relatively insensitive to the environment and fluoresces in both water-soluble and lipid environments .
    BODIPY <em>FL</em> C5
  • HY-D2286

    Fluorescent Dye Others
    HBT-Fl-BnB is a fluorescent probe for the ratiometric detection of ONOO - in vitro and in vivo. HBT-Fl-BnB consists of an HBT core with Fl groups at the ortho and para positions responding to the zwitterionic excited-state intramolecular proton-transfer (zwitterionic ESIPT) process and a boronic acid pinacol ester with dual roles that block the zwitterionic ESIPT and recognize ONOO - .
    HBT-<em>Fl</em>-BnB
  • HY-D1609

    Fluorescent Dye Others
    BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1 .
    BODIPY <em>FL</em> Verapamil hydrochloride
  • HY-D1602

    Fluorescent Dye Others
    BODIPY FL DHPE is a green-fluorescent phospholipid probe. BODIPY FL DHPE labels lipid 1,2-dihexadecanoyl-sn-glycero-phosphoethanolamine (DHPE), labeled liposomes can be internalized by membrane fusion. BODIPY FL DHPE can be used for investigations of membrane surface and membrane fusion. (λex=505 nm, λem=511 nm) .
    BODIPY <em>FL</em>-DHPE
  • HY-D1607

    Fluorescent Dye Others
    BODIPY FL SSE is a potent fluorescent dye. BODIPY FL SSE is used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY FL SSE can reactive with primary amines on biomolecules to emit green fluorescence. (λex=502 nm, λem=511 nm) .
    BODIPY <em>FL</em> SSE
  • HY-D1604

    Fluorescent Dye Others
    BODIPY FL Ethylamine is a fluorescent dye that reversibly reacts with aldehyde/ketone to yield a Schiff base. BODIPY FL Ethylamine can be reduced to form a stable amine derviative using sodium borohydride or sodium cyanoborohydride .
    BODIPY <em>FL</em> Ethylamine
  • HY-114350

    Fluorescent Dye Others
    BDP FL maleimide is a thiol-reactive dye (Ex: 503 nm; Em: 509 nm). BDP FL maleimide can be used for protein labeling, peptide modification, and can replace fluorescein (FAM) for microscopy .
    BDP <em>FL</em> maleimide
  • HY-160257

    Biochemical Assay Reagents Liposome Fluorescent Dye Others
    DOPE-PEG-BDP FL,MW 5000 is a PEG-lipid-dye conjugate consists of a DOPE phospholipid which is an unsaturated phospholipid, a BDP FL fluorophore with featuring excitation and emission maxima at 504 and 514 nm respectively and a large PEG spacer which links the former substance together.
    DOPE-PEG-BDP <em>FL</em>,MW 5000
  • HY-111102

    BRD4-IN-1

    Epigenetic Reader Domain Cancer
    FL-411 is a potent and selective BRD4 inhibitor with an IC50 of 0.43±0.09 μM for BRD4(1).
    <em>FL</em>-411
  • HY-140296

    Fluorescent Dye Others
    BDP FL DBCO is a photostable boron dipyrromethene used in the FAM (fluorescein) channel, with compatible property for fluorescein filters. BDP FL DBCO contains DBCO (azadibenzocyclooctyne) groups that enable copper-free catalyzed click chemistry reactions with azides. λex/λem= 503 nm/512 nm .
    BDP <em>FL</em> DBCO
  • HY-D2301

    Fluorescent Dye Others
    mgc(3Me)FL is the active fluorescent form of mgc(3Me)FDA (HY-D2300) after hydrolysis in cells. mgc(3Me)FL subcellularly localizes to the Golgi apparatus and is a visualized Golgi probe. mgc(3Me)FL also binds to the outer leaflet of the plasma membrane (PM), causing the plasma membrane to fluoresce .
    mgc(3Me)<em>FL</em>
  • HY-114351

    Fluorescent Dye Others
    BODIPY FL Hydrazide is a green-fluorescent dye, BODIPY FL Hydrazide is reactive with aldehyde/ketone on polysaccharides and glycoproteins, yielding a reversible Schiff base product that can be transformed to a stable linkage using a reducing agent like sodium borohydride or sodium cyanoborohydride. (λex=495 nm, λem=516 nm) .
    BODIPY <em>FL</em> hydrazide
  • HY-D1605

    Fluorescent Dye Others
    BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm) .
    BODIPY <em>FL</em> L-Cystine
  • HY-D1606

    Adrenergic Receptor Metabolic Disease
    BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with Ki values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes .
    BODIPY <em>FL</em> prazosin
  • HY-110257

    Fluorescent Dye Others
    BODIPY FL-X,SE is a fluorescent greendye for the labeling of amine, shows a high fluorescence quantum yield and is relatively insensitive to pH change. BODIPY FL-X,SE can be used as an alternative for FAM, Cy2 or FITC. λabs: 504 nm; λem:510 nm .
    BDY <em>FL</em>-X, SE
  • HY-152231

    Ligands for E3 Ligase Others
    BODIPY FL thalidomide is a high-affinity fluorescent probe for the human cereblon protein with a Kd value of 3.6 nM [1]
    BODIPY <em>FL</em> thalidomide
  • HY-15792

    10,11-(Methylenedioxy)-20(R)-camptothecin

    Others Cancer
    (R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118 (HY-12486). (R)-FL118 shows anticancer activity .
    (R)-<em>FL</em>118
  • HY-114346A

    Fluorescent Dye Others
    ODIPY FL EDA free base is an amine-based, green fluorescent probe. The R-NH2 of ODIPY FL EDA free base can be coupled with aldehydes or ketones to form reversible Schiff base products. Convert to stable amine derivatives using reducing agents such as sodium borohydride or sodium cyanoborohydride. ODIPY FL EDA free base can be used to detect modified or normal deoxynucleotides and demonstrate DNA damage and genomic DNA methylation.
    BODIPY <em>FL</em> EDA free base
  • HY-12486

    10,11-(Methylenedioxy)-20(S)-camptothecin

    Survivin Apoptosis IAP Cancer
    FL118 (10,11-(Methylenedioxy)-20(S)-camptothecin), a Camptothecin (HY-16560) analogue, is a potent and orally active survivin inhibitor. FL118 binds to oncoprotein DDX5 (p68) to dephosphorylates and degrades DDX5. FL118 can be used for the research of cancer .
    <em>FL</em>118
  • HY-161022S

    Isotope-Labeled Compounds ADC Linker Others
    FL118-C3-O-C-amide-C-NH2-d5 is a deuterium labeled FL118-C3-O-C-amide-C-NH2 .
    <em>FL</em>118-C3-O-C-amide-C-NH2-d5
  • HY-161022S1

    Isotope-Labeled Compounds ADC Linker Cancer
    FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    <em>FL</em>118-C3-O-C-amide-C-NH2-d5 formate
  • HY-135083

    PROTAC Linkers Cancer
    BDP FL-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    BDP <em>FL</em>-PEG4-amine
  • HY-141086

    PROTAC Linkers Cancer
    BDP FL-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    BDP <em>FL</em>-PEG5-azide
  • HY-141087

    PROTAC Linkers Cancer
    BDP FL-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    BDP <em>FL</em>-PEG5-propargyl
  • HY-141088

    PROTAC Linkers Cancer
    BDP FL-PEG4-TCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
    BDP <em>FL</em>-PEG4-TCO
  • HY-D1613

    Fluorescent Dye Others
    BODIPY FL C5-HPC is a lipophilic green fluorescent dye (Ex/Em: 500/510 nm) .
    BODIPY <em>FL</em> C5-HPC
  • HY-161022

    ADC Linker Cancer
    FL118-C3-O-C-amide-C-NH2 (compound 6a) is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
    <em>FL</em>118-C3-O-C-amide-C-NH2
  • HY-D1611

    Fluorescent Dye Others
    BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .
    BODIPY <em>FL</em>-C5 NHS Ester
  • HY-161022A

    ADC Linker Cancer
    FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..
    <em>FL</em>118-C3-O-C-amide-C-NH2 formate
  • HY-114353

    Fluorescent Dye Others
    BDP FL azide is a BDP dye connector containing an azide group capable of Click Chemistry. The green fluorophore is representative of the borodipyrromethane class of fluorescent dyes and has a high quantum yield in aqueous environments, high stability to photobleaching and is compatible with FAM fluorescence measurement instruments .
    BDP <em>FL</em> azide
  • HY-15533
    LY 3000328
    5 Publications Verification

    Z-FL-COCHO

    Cathepsin Inflammation/Immunology
    LY 3000328 (Z-FL-COCHO) is a potent and selective Cathepsin S (Cat S) inhibitor with IC50s of 7.7 and 1.67 nM for hCat S and mCat S, respectively.
    LY 3000328
  • HY-D1612

    Fluorescent Dye Others
    The Golgi apparatus is composed of flattened vesicles superimposed on each other by unit membranes. The flattened vesicles are round with expanded and perforated edges. The Golgi fluorescent probe is a BODIPY-labeled ceramide derivative, the synthesis of which occurs in the endoplasmic reticulum and can then be transported to the Golgi via ceramide transport protein (CERT) or vesicular translocation, allowing specific labeling of the dye . BODIPY Fl C5-Ceramide is a Golgi-specific green fluorescent dye, which can visualise individual cells . Ex/Em= 505 nm/512 nm.
    BODIPY <em>FL</em> C5-Ceramide

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