2. Others Antibody-drug Conjugate/ADC Related
  3. Isotope-Labeled Compounds ADC Linker
  4. FL118-C3-O-C-amide-C-NH2-d5 formate

FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

FL118-C3-O-C-amide-C-NH2-d<sub>5</sub> formate Chemical Structure

FL118-C3-O-C-amide-C-NH2-d5 formate Chemical Structure

Size Price Stock Quantity
1 mg USD 740 In-stock
5 mg USD 1850 In-stock
10 mg USD 2980 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of FL118-C3-O-C-amide-C-NH2-d5 formate:

FL118-C3-O-C-amide-C-NH2-d5 formate Related Antibodies

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Description

FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Molecular Weight

587.59

Formula

C28H25D5N4O10
Appearance

Solid

SMILES

NCC(NCOCCCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)C([2H])([2H])C([2H])([2H])[2H])=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.OC=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (170.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7019 mL 8.5093 mL 17.0187 mL
5 mM 0.3404 mL 1.7019 mL 3.4037 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7019 mL 8.5093 mL 17.0187 mL 42.5467 mL
5 mM 0.3404 mL 1.7019 mL 3.4037 mL 8.5093 mL
10 mM 0.1702 mL 0.8509 mL 1.7019 mL 4.2547 mL
15 mM 0.1135 mL 0.5673 mL 1.1346 mL 2.8364 mL
20 mM 0.0851 mL 0.4255 mL 0.8509 mL 2.1273 mL
25 mM 0.0681 mL 0.3404 mL 0.6807 mL 1.7019 mL
30 mM 0.0567 mL 0.2836 mL 0.5673 mL 1.4182 mL
40 mM 0.0425 mL 0.2127 mL 0.4255 mL 1.0637 mL
50 mM 0.0340 mL 0.1702 mL 0.3404 mL 0.8509 mL
60 mM 0.0284 mL 0.1418 mL 0.2836 mL 0.7091 mL
80 mM 0.0213 mL 0.1064 mL 0.2127 mL 0.5318 mL
100 mM 0.0170 mL 0.0851 mL 0.1702 mL 0.4255 mL
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FL118-C3-O-C-amide-C-NH2-d5 formate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FL118-C3-O-C-amide-C-NH2-d5 formateIsotope-Labeled CompoundsADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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FL118-C3-O-C-amide-C-NH2-d5 formate
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