FL118-C3-O-C-amide-C-NH2-d5 formate
Based on 1 Customer Validation
FL118-C3-O-C-amide-C-NH2-d5 formate is a deuterium labeled FL118-C3-O-C-amide-C-NH2 formate. FL118-C3-O-C-amide-C-NH2 formate is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
For research use only. We do not sell to patients.
- Formula: C28H25D5N4O10
- Molecular Weight:587.59
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 2821769-41-7
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Appearance Solid
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Molecular Weight 587.59
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Formula C28H25D5N4O10
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SMILES
NCC(NCOCCCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)C([2H])([2H])C([2H])([2H])[2H])=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.OC=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 100 mg/mL (170.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7019 mL | 8.5093 mL | 17.0187 mL | 42.5467 mL |
| 5 mM | 0.3404 mL | 1.7019 mL | 3.4037 mL | 8.5093 mL | |
| 10 mM | 0.1702 mL | 0.8509 mL | 1.7019 mL | 4.2547 mL | |
| 15 mM | 0.1135 mL | 0.5673 mL | 1.1346 mL | 2.8364 mL | |
| 20 mM | 0.0851 mL | 0.4255 mL | 0.8509 mL | 2.1273 mL | |
| 25 mM | 0.0681 mL | 0.3404 mL | 0.6807 mL | 1.7019 mL | |
| 30 mM | 0.0567 mL | 0.2836 mL | 0.5673 mL | 1.4182 mL | |
| 40 mM | 0.0425 mL | 0.2127 mL | 0.4255 mL | 1.0637 mL | |
| 50 mM | 0.0340 mL | 0.1702 mL | 0.3404 mL | 0.8509 mL | |
| 60 mM | 0.0284 mL | 0.1418 mL | 0.2836 mL | 0.7091 mL | |
| 80 mM | 0.0213 mL | 0.1064 mL | 0.2127 mL | 0.5318 mL | |
| 100 mM | 0.0170 mL | 0.0851 mL | 0.1702 mL | 0.4255 mL |