FL118-C3-O-C-amide-C-NH2 formate

Name: FL118-C3-O-C-amide-C-NH2 formate
Brand: MedChemExpress
SKU: HY-161022A
Rating: 4.5 (1 reviews)

製品番号: HY-161022A 純度: 96.49%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

FL118-C3-O-C-amide-C-NH2 formate 構造式

容量	価格（税別）	在庫状況	数量
1 mg	$350	在庫あり	Estimated Time of Arrival: December 31
5 mg	$780	在庫あり	Estimated Time of Arrival: December 31
10 mg	$1180	在庫あり	Estimated Time of Arrival: December 31
50 mg		お問い合わせ
100 mg		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 1 publication(s) in Google Scholar

Other Forms of FL118-C3-O-C-amide-C-NH2 formate:

FL118-C3-O-C-amide-C-NH2-d₅ formate 在庫あり
FL118-C3-O-C-amide-C-NH2-d₅ お問い合わせ
FL118-C3-O-C-amide-C-NH2 お問い合わせ

ADC Linker アイソフォーム固有の製品をすべて表示:

すべてのアイソフォームを表示

Cleavable Linker Non-cleavable Linker Acid Cleavable Linker Disulfide Cleavable Linker Protease Cleavable Linker Glycosidase Cleavable Linker Phosphatase Cleavable Linker

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..

体外実験

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

582.56

分子式

C₂₈H₃₀N₄O₁₀

Appearance

Solid

Color

White to yellow

SMILES

NCC(NCOCCCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.O=CO

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶剤 & 溶解度

体外:

DMSO : 100 mg/mL (171.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7166 mL	8.5828 mL	17.1656 mL
5 mM	0.3433 mL	1.7166 mL	3.4331 mL
10 mM	0.1717 mL	0.8583 mL	1.7166 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 96.49%

Select Batch:

データシート (272 KB) SDS (252 KB)

COA (253 KB) HNMR (338 KB) LCMS (108 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Song Shuai, et al. Preparation method for drug linker conjugate. WO2023143208A1.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.7166 mL	8.5828 mL	17.1656 mL	42.9140 mL
	5 mM	0.3433 mL	1.7166 mL	3.4331 mL	8.5828 mL
	10 mM	0.1717 mL	0.8583 mL	1.7166 mL	4.2914 mL
	15 mM	0.1144 mL	0.5722 mL	1.1444 mL	2.8609 mL
	20 mM	0.0858 mL	0.4291 mL	0.8583 mL	2.1457 mL
	25 mM	0.0687 mL	0.3433 mL	0.6866 mL	1.7166 mL
	30 mM	0.0572 mL	0.2861 mL	0.5722 mL	1.4305 mL
	40 mM	0.0429 mL	0.2146 mL	0.4291 mL	1.0729 mL
	50 mM	0.0343 mL	0.1717 mL	0.3433 mL	0.8583 mL
	60 mM	0.0286 mL	0.1430 mL	0.2861 mL	0.7152 mL
	80 mM	0.0215 mL	0.1073 mL	0.2146 mL	0.5364 mL
	100 mM	0.0172 mL	0.0858 mL	0.1717 mL	0.4291 mL