2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. FL118-C3-O-C-amide-C-NH2 formate

FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..

For research use only. We do not sell to patients.

FL118-C3-O-C-amide-C-NH2 formate Chemical Structure

FL118-C3-O-C-amide-C-NH2 formate Chemical Structure

Size Price Stock Quantity
5 mg USD 180 In-stock
10 mg USD 290 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of FL118-C3-O-C-amide-C-NH2 formate:

FL118-C3-O-C-amide-C-NH2 formate Related Antibodies

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Description

FL118-C3-O-C-amide-C-NH2 format is an ADC linker for the synthesis of synthetic antibody conjugate active molecules (ADCs)..

Molecular Weight

582.56

Formula

C28H30N4O10
Appearance

Solid

Color

Light yellow to yellow

SMILES

NCC(NCOCCCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC(OCO6)=C6C=C51)=O.O=CO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (171.66 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7166 mL 8.5828 mL 17.1656 mL
5 mM 0.3433 mL 1.7166 mL 3.4331 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.7166 mL 8.5828 mL 17.1656 mL 42.9140 mL
5 mM 0.3433 mL 1.7166 mL 3.4331 mL 8.5828 mL
10 mM 0.1717 mL 0.8583 mL 1.7166 mL 4.2914 mL
15 mM 0.1144 mL 0.5722 mL 1.1444 mL 2.8609 mL
20 mM 0.0858 mL 0.4291 mL 0.8583 mL 2.1457 mL
25 mM 0.0687 mL 0.3433 mL 0.6866 mL 1.7166 mL
30 mM 0.0572 mL 0.2861 mL 0.5722 mL 1.4305 mL
40 mM 0.0429 mL 0.2146 mL 0.4291 mL 1.0729 mL
50 mM 0.0343 mL 0.1717 mL 0.3433 mL 0.8583 mL
60 mM 0.0286 mL 0.1430 mL 0.2861 mL 0.7152 mL
80 mM 0.0215 mL 0.1073 mL 0.2146 mL 0.5364 mL
100 mM 0.0172 mL 0.0858 mL 0.1717 mL 0.4291 mL
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FL118-C3-O-C-amide-C-NH2 formate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FL118-C3-O-C-amide-C-NH2 formateADC LinkerAntibody-drug conjugates linkerADCInhibitorinhibitorinhibit

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FL118-C3-O-C-amide-C-NH2 formate
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