PSG1 Protein, Human (HEK293, His)
Based on 1 Customer Validation
PSG1 Protein is extremely vital to development and health of a fetus. PSG1 Protein is important in inducing, enhancing or inhibiting an immune response. PSG1 Protein, Human (HEK293, His) is the recombinant human-derived PSG1 protein, expressed by HEK293 , with C-6*His labeled tag.
- Species: Human
- Source: HEK293
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Storage:Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
PSG1 Protein is extremely vital to development and health of a fetus. PSG1 Protein is important in inducing, enhancing or inhibiting an immune response[1][2]. PSG1 Protein, Human (HEK293, His) is the recombinant human-derived PSG1 protein, expressed by HEK293 , with C-6*His labeled tag.
Background
PSG1 Protein is a secreted glycoprotein of the human PSG family[3]. PSG1 Protein is the most abundant PSG in maternal serum, as a possible inducer of proangiogenic growth factors known to play an important role in establishment of the vasculature at the maternal-fetal interface[4]. PSG1 Protein functions primarily as an immune-modulator to protect the growing fetus[5].
MCE Validation Data
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Purity - SDS-PAGE
Purity - SDS-PAGE
Technical Parameters
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Species Human
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Source HEK293
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Tag C-6*His
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Accession
P11464-1/NP_001171754.1 (Q35-P419)
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Molecular Construction
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N-term
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PSG1 (Q35-P419)
Accession # P11464-1/NP_001171754.1 -
6*His
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C-term
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Protein Length
Full Length of Mature Protein
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Synonyms
PSG1; B1G1; Prev. PSBG1; Pregnancy Specific Beta-1-Glycoprotein 1, Isoform CRA_h; PSGGA; Pregnancy-Specific Beta-1 Glycoprotein; Pregnancy-Specific Beta-1-Glycoprotein 1; Pregnancy-Specific B-1 Glycoprotein; CD66f; Pregnancy-Specific Glycoprotein 1; PBG1;
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AA Sequence
QVTIEAEPTKVSEGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEVSDWTVP
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Predicted Molecular Mass
44.5 kDa
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Molecular Weight
Approximately 68 kDa, based on SDS-PAGE under reducing conditions.
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Glycosylation
Yes
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Purity
≥ 95%, as determined by reducing SDS-PAGE.
Product Properties
Lyophilized powder.
Lyophilized from a 0.22 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
<1 EU/μg, determined by LAL method.
It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).
Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.
Room temperature in continental US; may vary elsewhere.
Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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