2. Apoptosis
  3. Apoptosis
  4. FL77-24

FL77-24  (Synonyms: 7-(4-Ethylphenyl)-FL118)

Cat. No.: HY-157419
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FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, <6.4 nM, 28.5 nM and <6.4 nM in HCT116, HepG2, MCF-7, A549 and HeLa cells, respectively. FL77-24 mainly causes cell cycle arrest in S and G2/M phases.

For research use only. We do not sell to patients.

FL77-24 Chemical Structure

FL77-24 Chemical Structure

CAS No. : 2413582-39-3

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Description

FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, <6.4 nM, 28.5 nM and <6.4 nM in HCT116, HepG2, MCF-7, A549 and HeLa cells, respectively. FL77-24 mainly causes cell cycle arrest in S and G2/M phases[1].

Molecular Weight

528.51

Formula

C29H24N2O8
CAS No.
SMILES

CC[C@]1(C(OCC2=C1C=C3C4=NC5=C(C(C6=CC(OC)=CC(OC)=C6)=C4CN3C2=O)C=C7OCOC7=C5)=O)O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FL77-24 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FL77-242413582-39-37-(4-Ethylphenyl)-FL118ApoptosisAntitumor activity,Apoptosis,Cancer,Cells,GeneticsInhibitorinhibitorinhibit

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