2413582-39-3
2413582-39-3
Chemical Structure
FL77-24
Synonym(s): 7-(4-Ethylphenyl)-FL118
- CAS No.: 2413582-39-3
- Formula:C29H24N2O8
- Molecular Weight:528.51
InChIKey: AFBSZCMKFZHQHQ-LJAQVGFWSA-N
SMILES: CC[C@]1(C(OCC2=C1C=C3C4=NC5=C(C(C6=CC(OC)=CC(OC)=C6)=C4CN3C2=O)C=C7OCOC7=C5)=O)O
Biological Activity: FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, <6.4 nM, 28.5 nM and <6.4 nM in HCT116, HepG2, MCF-7, A549 and HeLa cells, respectively. FL77-24 mainly causes cell cycle arrest in S and G2/M phases[1].
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FL77-24 | FL77-24, a FL118 analog and apoptosis inducer, possesses antitumor activity, with IC50 values of 99.4 nM, 118 nM, <6.4 nM, 28.5 nM and <6.4 nM in HCT116, HepG2, MCF-7, A549 and HeLa cells, respectively. FL77-24 mainly causes cell cycle arrest in S and G2/M phases. | |||||||||||||||||||||
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References
Keywords
