BODIPY FL L-Cystine
Based on 1 publication(s) in Google Scholar
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm).
For research use only. We do not sell to patients.
- Purity: 99.14%
- CAS No.: 1180490-57-6
- Formula: C34H38B2F4N6O6S2
- Molecular Weight:788.45
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) BODIPY FL L-Cystine
More
Biological Activity
BODIPY FL L-Cystine is composed of two BODIPY molecules and a cysteine residue for detection of reducing environments or the degradation process of disulfide-containing molecules.
BODIPY FL L-Cystine can be labeled to disulfide-containing polymers (such as PEI or pLL). As the disulfide bonds on the polymer be cut by the reducing environment, the self-quenching effect will be reduced, and the fluorescence intensity is increased[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
510
502
Chemical Information
-
CAS No. 1180490-57-6
-
Appearance Solid
-
Molecular Weight 788.45
-
Formula C34H38B2F4N6O6S2
-
Color Orange to red
-
SMILES
[F-][B+3]([F-])([N-]12)[N]3=C(C)C=C(C)C3=CC1=CC=C2CCC(N[C@@H](CSSC[C@@H](C(O)=O)NC(CCC4=CC=C5[N-]4[B+3]([F-])([F-])[N]6=C(C)C=C(C)C6=C5)=O)C(O)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Redox Biol
Molecular determinants of allosteric modulation of protein disulfide isomerase by small-molecule b'-ligands. [Abstract]2026 Mar:90:104044. PMID: 41610518
Solvent & Solubility
DMSO : 50 mg/mL (63.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (275 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
[1]. Hofmann L, et, al. An effective thiol-reactive probe for differential scanning fluorimetry with a standard real-time polymerase chain reaction device. Anal Biochem. 2016 Apr 15;499:63-65. [Content Brief]
[2]. Kumar D, et, al. Glutathione-mediated release of Bodipy® from PEG cofunctionalized gold nanoparticles. Int J Nanomedicine. 2012;7:4007-22. [Content Brief]
[3]. Hozsa C, et al., Monitoring the degradation of reduction-sensitive gene carriers with fluorescence spectroscopy and flow cytometry. Methods Mol Biol. 2013;991:171-84. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2683 mL | 6.3416 mL | 12.6831 mL | 31.7078 mL |
| 5 mM | 0.2537 mL | 1.2683 mL | 2.5366 mL | 6.3416 mL | |
| 10 mM | 0.1268 mL | 0.6342 mL | 1.2683 mL | 3.1708 mL | |
| 15 mM | 0.0846 mL | 0.4228 mL | 0.8455 mL | 2.1139 mL | |
| 20 mM | 0.0634 mL | 0.3171 mL | 0.6342 mL | 1.5854 mL | |
| 25 mM | 0.0507 mL | 0.2537 mL | 0.5073 mL | 1.2683 mL | |
| 30 mM | 0.0423 mL | 0.2114 mL | 0.4228 mL | 1.0569 mL | |
| 40 mM | 0.0317 mL | 0.1585 mL | 0.3171 mL | 0.7927 mL | |
| 50 mM | 0.0254 mL | 0.1268 mL | 0.2537 mL | 0.6342 mL | |
| 60 mM | 0.0211 mL | 0.1057 mL | 0.2114 mL | 0.5285 mL |
BODIPY FL L-Cystine Related Classifications
HY-D1605 Related Classifications
Powered by Bioz