BODIPY FL L-Cystine

Name: BODIPY FL L-Cystine
Brand: MedChemExpress
SKU: HY-D1605
Rating: 4.5 (1 reviews)

Cat. No.: HY-D1605 Purity: 99.14%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λ_ex=504 nm, λ_em=511 nm).

For research use only. We do not sell to patients.

BODIPY FL L-Cystine Chemical Structure

CAS No. : 1180490-57-6

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE BODIPY FL L-Cystine

•Redox Biol. 2026 Mar:90:104044. [Abstract]

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

BODIPY FL L-Cystine is composed of two BODIPY molecules and a cysteine residue for detection of reducing environments or the degradation process of disulfide-containing molecules.
BODIPY FL L-Cystine can be labeled to disulfide-containing polymers (such as PEI or pLL). As the disulfide bonds on the polymer be cut by the reducing environment, the self-quenching effect will be reduced, and the fluorescence intensity is increased^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

788.45

Formula

C₃₄H₃₈B₂F₄N₆O₆S₂

CAS No.

1180490-57-6

Appearance

Solid

Color

Orange to red

Emission (Em)

510

Excitation (Ex)

502

SMILES

[F-][B+3]([F-])([N-]12)[N]3=C(C)C=C(C)C3=CC1=CC=C2CCC(N[C@@H](CSSC[C@@H](C(O)=O)NC(CCC4=CC=C5[N-]4[B+3]([F-])([F-])[N]6=C(C)C=C(C)C6=C5)=O)C(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (63.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.2683 mL	6.3416 mL	12.6831 mL
5 mM	0.2537 mL	1.2683 mL	2.5366 mL
10 mM	0.1268 mL	0.6342 mL	1.2683 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.14%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (252 KB) HNMR (229 KB) CNMR (114 KB) LCMS (179 KB)

Handling Instructions (2659 KB)

References

[1]. Hofmann L, et, al. An effective thiol-reactive probe for differential scanning fluorimetry with a standard real-time polymerase chain reaction device. Anal Biochem. 2016 Apr 15;499:63-65. [Content Brief]

[2]. Kumar D, et, al. Glutathione-mediated release of Bodipy® from PEG cofunctionalized gold nanoparticles. Int J Nanomedicine. 2012;7:4007-22. [Content Brief]

[3]. Hozsa C, et al., Monitoring the degradation of reduction-sensitive gene carriers with fluorescence spectroscopy and flow cytometry. Methods Mol Biol. 2013;991:171-84. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.2683 mL	6.3416 mL	12.6831 mL	31.7078 mL
	5 mM	0.2537 mL	1.2683 mL	2.5366 mL	6.3416 mL
	10 mM	0.1268 mL	0.6342 mL	1.2683 mL	3.1708 mL
	15 mM	0.0846 mL	0.4228 mL	0.8455 mL	2.1139 mL
	20 mM	0.0634 mL	0.3171 mL	0.6342 mL	1.5854 mL
	25 mM	0.0507 mL	0.2537 mL	0.5073 mL	1.2683 mL
	30 mM	0.0423 mL	0.2114 mL	0.4228 mL	1.0569 mL
	40 mM	0.0317 mL	0.1585 mL	0.3171 mL	0.7927 mL
	50 mM	0.0254 mL	0.1268 mL	0.2537 mL	0.6342 mL
	60 mM	0.0211 mL	0.1057 mL	0.2114 mL	0.5285 mL