BODIPY FL Verapamil hydrochloride
BODIPY FL Verapamil hydrochloride is a fluorescent dye, it can be used as a molecular probe to label tissues and cells. BODIPY FL Verapamil hydrochloride is a substrate for both ABCB1 and ABCC1.
For research use only. We do not sell to patients.
- CAS No.: 216571-88-9
- Formula: C41H56BClF2N4O5
- Molecular Weight:769.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
BODIPY FL Verapamil hydrochloride (10 μM) can be incubated with removed tissue in phosphate buffered solution to demonstrate binding site[1]. BODIPY FL Verapamil hydrochloride (0-100 nM) inhibits ABCB1 and ABCC1 efflux with loxapine, mometasone, nicardipine, pimozide and verapamil with IC50 values of 1.6-15.6 nM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 216571-88-9
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Molecular Weight 769.17
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Formula C41H56BClF2N4O5
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SMILES
O=C(CCC1=CC=C2C=C3C(C)=CC(C)=[N]3[B+3]([F-])([N-]21)[F-])NCC(CCCN(CCC4=CC=C(C(OC)=C4)OC)C)(C(C)C)C5=CC=C(C(OC)=C5)OC.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Just S, et al. Histological demonstration of voltage dependent calcium channels on calcitonin gene-related peptide-immunoreactive nerve fibres in the mouse knee joint. Neurosci Lett. 2001 Oct 26;312(3):133-6. [Content Brief]
[2]. Strouse JJ, et al. Fluorescent substrates for flow cytometric evaluation of efflux inhibition in ABCB1, ABCC1, and ABCG2 transporters. Anal Biochem. 2013 Jun 1;437(1):77-87. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BODIPY FL Verapamil hydrochloride Related Classifications
HY-D1609 Related Classifications
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