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Results for "

Nanrilkefusp alfa

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (1) Amyloid-β (1) Apoptosis (3) Bacterial (1) Biochemical Assay Reagents (9) Caspase (1) CD19 (1) CD20 (2) CD276/B7-H3 (1) CD28 (1) CD3 (2) CD38 (1) CD47 (1) CD73 (1) Complement System (1) DNA/RNA Synthesis (1) Drug Derivative (3) EGFR (4) Endogenous Metabolite (4) Endonuclease (1) Estrogen Receptor/ERR (3) Factor VIIa (1) Factor VIII (4) Factor XI (1) Fc Receptor (FcR) (1) FGFR (1) GCGR (1) GHR (1) GLP Receptor (2) Glycosidase (4) GnRH Receptor (1) HCV (1) HIV (2) IFNAR (2) IGF-1R (1) Insulin Receptor (3) Integrin (2) Interleukin Related (21) Kallikrein (1) MHC (1) NO Synthase (1) NTPDase (2) Orexin Receptor (OX Receptor) (1) Parasite (1) PD-1/PD-L1 (5) Phosphatase (2) Phosphodiesterase (PDE) (1) RXFP Receptor (2) Ser/Thr Protease (1) STAT (2) Steroid Sulfatase (1) TGF-beta/Smad (2) TGF-β Receptor (4) TNF Receptor (5) Transferrin Receptor (3) Transmembrane Glycoprotein (2) VEGFR (5)
By Research Areas:	Cancer (44) Cardiovascular Disease (14) Endocrinology (5) Infection (7) Inflammation/Immunology (52) Metabolic Disease (15) Neurological Disease (5)

By Targets:

Akt (1)

Amyloid-β (1)

Apoptosis (3)

Bacterial (1)

Biochemical Assay Reagents (9)

Caspase (1)

CD19 (1)

CD20 (2)

CD276/B7-H3 (1)

CD28 (1)

CD3 (2)

CD38 (1)

CD47 (1)

CD73 (1)

Complement System (1)

DNA/RNA Synthesis (1)

Drug Derivative (3)

EGFR (4)

Endogenous Metabolite (4)

Endonuclease (1)

Estrogen Receptor/ERR (3)

Factor VIIa (1)

Factor VIII (4)

Factor XI (1)

Fc Receptor (FcR) (1)

FGFR (1)

GCGR (1)

GHR (1)

GLP Receptor (2)

Glycosidase (4)

GnRH Receptor (1)

HCV (1)

HIV (2)

IFNAR (2)

IGF-1R (1)

Insulin Receptor (3)

Integrin (2)

Interleukin Related (21)

Kallikrein (1)

MHC (1)

NO Synthase (1)

NTPDase (2)

Orexin Receptor (OX Receptor) (1)

Parasite (1)

PD-1/PD-L1 (5)

Phosphatase (2)

Phosphodiesterase (PDE) (1)

RXFP Receptor (2)

Ser/Thr Protease (1)

STAT (2)

Steroid Sulfatase (1)

TGF-beta/Smad (2)

TGF-β Receptor (4)

TNF Receptor (5)

Transferrin Receptor (3)

Transmembrane Glycoprotein (2)

VEGFR (5)

By Research Areas:

Cancer (44)

Cardiovascular Disease (14)

Endocrinology (5)

Infection (7)

Inflammation/Immunology (52)

Metabolic Disease (15)

Neurological Disease (5)

111

Inhibitors & Agonists

Peptides

116

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-108903

Hyaluronidase (human recombinant) Maximum Cited Publications 16 Publications Verification Vorhyaluronidase alfa; rHuPH 20	Biochemical Assay Reagents Glycosidase	Metabolic Disease
Hyaluronidase (human recombinant) (Vorhyaluronidase alfa; rHuPH 20) is an enzyme that catalyzes the degradation of hyaluronic acid. Hyaluronidase (human recombinant) is used to improve the absorption and dispersal of parenteral fluids, medications, and contrast media .

HY-P99367

Ifinatamab DS-7300a Antibody; MABX-9001A Antibody	CD276/B7-H3	Inflammation/Immunology Cancer
Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .

HY-147305

Efgartigimod alfa ARGX-113	Fc Receptor (FcR)	Inflammation/Immunology
Efgartigimod alfa (ARGX-113) is a reversibility, humanized ^Fc receptor antagonist . Efgartigimod alfa is a anti FcRn monoclonal immunoglobulin G (IgG1) Fc fragment. Efgartigimod reduces serum levels of total IgG, including pathogenic autoantibodies, by blocking FcRn function without permanent impairment. Efgartigimod alfa can be used for generalised myasthenia gravis (gMG) and primary immune thrombocytopenia research .

HY-108786

Asfotase alfa ENB-0040	Phosphatase	Metabolic Disease
Asfotase alfa (ENB-0040) is a bone-targeted genetically engineered glycoprotein. Asfotase alfa increases the survival rate, bone mineralization and bone length and prevents mineralization defects of the feet, rib cage, lower limbs, jaw bones in Akp2 ^/ knockout mice. Asfotase alfa can be used for the research of perinatal, infantile, and juvenile-onset hypophosphatasia (HPP) .

HY-P99908

Efineptakin alfa NT-17	Interleukin Related	Cancer
Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4 ⁺ and CD8 ⁺ cells in both human and mice. Efineptakin alfa can be used for glioblastoma research .

HY-P990964

Efimosfermin alfa BOS-580; LLF580	FGFR	Metabolic Disease Inflammation/Immunology
Efimosfermin alfa is a genetically engineered FGF21 variant. Efimosfermin alfa exerts its function by activating the FGFR1c/β-Klotho complex. Efimosfermin alfa is applicable to researches on metabolic dysfunction-associated steatohepatitis, obesity and mild hypertriglyceridemia .

HY-P99518

Taldefgrobep alfa BMS 986089; RG 6206; RO 7239361; BHV2000	TGF-beta/Smad	Others
Taldefgrobep alfa (BMS 986089; RG 6206; RO 7239361) is a protein that blocks myostatin. Taldefgrobep alfa is a fusion protein composed of a human IgG1-Fc domain and Adnectin domain. Taldefgrobep alfa can be used for spinal muscular atrophy (SMA) research .

HY-P99797

Pabinafusp alfa JR-141	Transferrin Receptor	Neurological Disease
Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .

HY-P990957

Ficerafusp alfa BCA-101; FMAB2	EGFR TGF-beta/Smad	Inflammation/Immunology Cancer
Ficerafusp alfa (BCA-101) is a bispecific antibody targeting EGFR and TGFβ, with a K_d of 2.58 nM against EGFR and a K_d of 61.3 nM against TGFβ1. Ficerafusp alfa binds to EGFR, inhibits EGFR phosphorylation, blocks EGF-dependent cell proliferation, and mediates antibody-dependent cellular cytotoxicity against EGFR-positive tumor cells. Ficerafusp alfa sequesters TGFβ via its TGFβRII ECD domain, neutralizes the activity of TGFβ and TGFβ1, and blocks TGFβ-dependent processes, including epithelial-mesenchymal transition, cell invasion, and differentiation of inducible regulatory T cells. Ficerafusp alfa is applicable to research related to head and neck squamous cell carcinoma, advanced solid tumors, squamous non-small cell lung cancer, anal squamous cell carcinoma, colorectal cancer, and pancreatic cancer .

HY-108858

Dornase alfa 1 Publications Verification rhDNase	DNA/RNA Synthesis Endonuclease	Inflammation/Immunology
Dornase alfa (rhDNase) is a recombinant human deoxyribonuclease I (rhDNase) that can specifically degrade extracellular DNA. Dornase alfa catalyzes the cleavage of DNA released by neutrophils in respiratory mucus, reduces sputum viscosity, thereby improving mucus clearance efficiency, reducing airway obstruction and alleviating inflammatory responses. Dornase alfa can be used to improve lung function (such as FEV_1) in cystic fibrosis (CF), reduce the risk of acute pulmonary exacerbations, and has good in vivo tolerability. Dornase alfa acts locally on the respiratory tract through aerosol inhalation, specifically improving the high viscosity of mucus caused by DNA accumulation and related respiratory symptoms .

HY-P99934

Eftozanermin alfa 1 Publications Verification ABBV-621	Apoptosis Caspase TNF Receptor	Cancer
Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with K_ds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies .

HY-P990724

Tividenofusp alfa DNL-310	Steroid Sulfatase	Metabolic Disease
Tividenofusp alfa (DNL‑310) is a modified iduronate‑2‑sulfatase fusion protein capable of crossing the blood-brain barrier. Tividenofusp alfa can be used in research on mucopolysaccharidosis type II .

HY-P99665

Insulin efsitora alfa LY-3209590	Insulin Receptor	Metabolic Disease
Insulin efsitora alfa (LY-3209590) is a selective agonist of insulin receptor (IR). Insulin efsitora alfa is a fusion protein composed of human IR agonists fused with the crystallizable (Fc) domain of human immunoglobulin G2 (IgG2) fragment, with a molecular weight of 64.1 kDa. Insulin efsitora alfa is well tolerated and has potential applications in diabetes .

HY-P99752

Nemvaleukin alfa ALKS 4230; RDB-1450	Interleukin Related	Inflammation/Immunology Cancer
Nemvaleukin alfa (ALKS 4230) is a IL-2 fusion protein that selectively binds to intermediate-affinity IL-2R. Nemvaleukin alfa is an activator of NK and effector T cells. Nemvaleukin alfa can be used for research of cancer .

HY-P99728

Melredableukin alfa RG7835; RO7049665	Interleukin Related	Metabolic Disease Inflammation/Immunology
Melredableukin alfa (RG7835) is a bivalent conjugate composed of a human IL-2 mutant (T3A, N88D, C125A) and human IgG1. Melredableukin alfa exhibits enhanced Treg cell selectivity in cynomolgus monkey and humanized mouse models. Melredableukin alfa can be used in research related to ulcerative colitis and autoimmune hepatitis .

HY-P99480

Bintrafusp alfa M7824; MSB0011359C	TGF-β Receptor	Cancer
Bintrafusp alfa (M 7824) is a first-in-class bifunctional fusion protein composed of the extracellular domain of TGF-βRII fused to a human IgG1 mAb blocking programmed cell death ligand. Bintrafusp alfa can be used for the research of cancer .

HY-P99944

SHR-1701 Retlirafusp alfa	PD-1/PD-L1 TGF-β Receptor	Cancer
SHR-1701 (Retlirafusp alfa) is a bifunctional fusion protein targeting PD-L1 and TGF-β for cancer research .

HY-108842

*Peginterferon alfa-2b* PegIFN a-2b; Sch 54031; Sylatron; ViraferonPeg	HIV HCV	Infection Cancer
Peginterferon alfa-2b (PegIFN a-2b; Sch 54031; Sylatron; ViraferonPeg) is an immunomodulator. Peginterferon alfa-2b is a recombinant alfa-2b interferon covalently linked PEG with antiviral activity against HCV. Peginterferon alfa-2b decreases viral DNA in HIV. Peginterferon alfa-2b can be used in research of melanoma and hepatitis C .

HY-P99905

Efdamrofusp alfa 1 Publications Verification IBI302	VEGFR	Cardiovascular Disease Neurological Disease
Efdamrofusp alfa is a bispecific fusion protein. Efdamrofusp alfa is capable of neutralizing both VEGF isoforms and C3b/C4b. Efdamrofusp alfa can be used for the research of neovascular age-related macular degeneration (nAMD) and other complement-related ocular conditions .

HY-P99479

Bifikafusp alfa L19-IL2	Interleukin Related	Cancer
Bifikafusp alfa (L19-IL2) is an immunoresearch fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity .

HY-P99917

Eflepedocokin alfa F-652; rhIL-22 dimer	STAT	Infection Inflammation/Immunology
Eflepedocokin alfa is a recombinant fusion protein. Eflepedocokin alfa consists of human IL-22 fused to human IgG2-Fc domain. Eflepedocokin alfa leads to the activation of IL-22/IL-22R-mediated signal transduction pathways as well as STAT3. Eflepedocokin alfa plays a role in immune response and bacterial infection, enhancing intestinal barrier function, intestinal immunity, and tissue repair .

HY-P991212

Berahyaluronidase alfa ALT-B4	Glycosidase	Cancer
Berahyaluronidase alfa (ALT-B4) is a recombinant hyaluronidase engineered from human hyaluronidase PH20. Berahyaluronidase alfa features favorable structural stability and enzymatic activity, and can be used to enhance drug absorption and dispersion in subcutaneous or intradermal administration .

HY-P99605

Cinrebafusp alfa PRS 343	EGFR TNF Receptor	Cancer
Cinrebafusp alfa (PRS 343) is a high affinity CD137/HER2 bispecfic anticalin-based drug. Cinrebafusp alfa binds to recombinant human HER2 (K_d=0.3 nM) and human monomeric CD137 (4-1BB; K_d=5 nM). Cinrebafusp alfa facilitates T-cell costimulation by tumor-localized, HER2-dependent 4-1BB clustering and activation, further enhancing T-cell receptor-mediated activity and leading to tumor destruction. Cinrebafusp alfa has the potential for HER2+ solid tumors research .

HY-P99902

Simlukafusp alfa FAP-IL2v; RO6874281; RG7461	Interleukin Related	Cancer
Simlukafusp alfa (FAP-IL2v) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAPα) and an IL-2 variant that only binds IL-2Rβγ. Isotype: human IgG1 .

HY-P99661

Inbakicept 2 Publications Verification	Interleukin Related	Cancer
Inbakicept is a dimeric human IL-15 receptor alpha (IL-15 Ra) sushi domain/human IgG1 Fc fusion protein and is an IL-15 superagonist complex. Inbakicept is able to form complex N-803 (Nogapendekin alfa inbakicept) with the IL-15 antibody Nogapendekin alfa in a 1:2 ratio. N-803 mimics the function of IL-15 and amplifies anti-CD20 mAb-mediated NK cell responses and antibody-dependent cellular cytotoxicity (ADCC). N-803 also increases degranulation and IFNγ production in cells .

HY-P99919

Efmarodocokin alfa 1 Publications Verification	Interleukin Related	Infection
Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia .

HY-P99348

*Ropeginterferon alfa-2b* Ropeginterferon alfa-2b-njft; PEG-proline-interferon alpha-2b	Apoptosis	Cancer
Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) is a monopegylated IFN-α that can be used for the research of myeloproliferative neoplasms .

HY-112998

Efmoroctocog alfa	Factor VIII	Cardiovascular Disease
Efmoroctocog alfa is a recombinant factor VIII-Fc fusion protein (rFVIIIFc). In mice with hemophilia A, Efmoroctocog alfa provides longer-lasting protection against tail vein transection injury than conventional rFVIII products. In dogs with hemophilia A, Efmoroctocog alfa produces a longer duration of improvement in whole blood clotting time than conventional rFVIII products. Efmoroctocog alfa can be used for research on hemophilia A .

HY-P99877

Efavaleukin alfa AMG592	Biochemical Assay Reagents	Inflammation/Immunology
Efavaleukin alfa (AMG592) is a IL-2 mutein fragment crystallizable fusion protein. Efavaleukin alfa drives the selective expansion of regulatory T cells. Efavaleukin alfa is applicable to research related to systemic lupus erythematosus .

HY-P99666

*Interferon alfa-2b*	IFNAR	Infection Cancer
Interferon alfa-2b is a type I interferon that activates novel genes and exerts potent antiviral and antiproliferative activity on target cells. Signaling by Interferon alfa-2b requires receptor-dependent activation of Stat1 and Stat2 to form a heterodimeric STAT that binds to the DNA-binding protein IRF-9 (p48) and forms ISGF-3 (IFN-stimulated gene factor 3). The driver genes are then further activated by ISGF-3 to achieve antiviral function .

HY-P99879

Efbemalenograstim alfa Benegrastim; Bineuta; F 627	STAT	Inflammation/Immunology
Efbemalenograstim alfa (F 627) is a recombinant fusion protein. Efbemalenograstim alfa is a long acting dimeric granulocyte colony-stimulating factor (G-CSF) that contains two human G-CSF fused to a human immunoglobulin G2 (hIgG2)-Fc fragment with a peptide linker. Efbemalenograstim alfa induces the production of white blood cells .

HY-P99744

Modakafusp alfa TAK-573	CD38	Inflammation/Immunology Cancer
Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice .

HY-P990017

Englumafusp alfa CD19-4-1BBL; RO7227166; RG6076	CD19	Cancer
Englumafusp alfa (CD19-4-1BBL; RO7227166) is a fusion construct comprised of a CD19-specific antibody domain fused to a trimerized extracellular domains of human 41BBL. Englumafusp alfa promotes CD19-specific 4-1BB cross-linking on the surface of T and NK cells .

HY-P990961

Palverafusp alfa IMM-2510; SYN-2510	VEGFR PD-1/PD-L1	Cardiovascular Disease Inflammation/Immunology Cancer
Palverafusp alfa (IMM-2510; SYN-2510) is a PD-L1/VEGF-targeting IgG1κ type humanized antibody. Palverafusp alfa blocks PD-1/PD-L1 binding, relieves immune suppression, mediates PD-L1-directed antibody-dependent cellular cytotoxicity (ADCC). Palverafusp alfa blocks VEGF/VEGFR binding, inhibits angiogenic signaling, relieves VEGF-induced immune suppression. Palverafusp alfa reduces endothelial cell proliferation, enhances ADCC and antibody-dependent cellular phagocytosis (ADCP), inhibits tumor growth, reverses T cell immune suppression. Palverafusp alfa exhibits immune stimulatory, antiangiogenic, and anti-tumor activity in the tumor microenvironment. Palverafusp alfa can be used for the research of cancer, such as solid tumors, non-small cell lung cancer .

HY-P99928

Efprezimod alfa MK 7110; CD24 Fc	Transmembrane Glycoprotein	Cancer
Efprezimod alfa (MK 7110; CD24 Fc) is a humanized CD24-Fc fusion protein. Efprezimod alfa enhances the interaction between CD24 and Siglec-10, thereby regulating the response of innate immune cells to damage-associated molecular patterns, inhibiting the activation of antigen-presenting cells and subsequent inflammatory responses. Efprezimod alfa is applicable to the research of acute graft-versus-host disease and acquired immunodeficiency syndrome .

HY-P990013

Gulgafafusp alfa Glutazumab; GMA-102; GMA-105	GCGR	Metabolic Disease
Gulgafafusp alfa is a human IgG2κ antibody targeting the glucagon-like peptide 1 receptor GLP1R .

HY-118860

Corifollitropin alfa Org 36286; MK-8962	Estrogen Receptor/ERR	Endocrinology
Corifollitropin alfa (Org 36286) is a long-acting recombinant follicle-stimulating hormone (FSH) analog. Corifollitropin alfa is a FSH Receptor agonist with an EC₅₀ of 5.0 pM. Corifollitropin alfa stimulates ovulation and can be used in the research of infertility .

HY-P99530

Valanafusp alfa AGT-181; HIRMAb-IDUA	Insulin Receptor	Metabolic Disease
Valanafusp alfa (AGT-181) is a chimeric monoclonal antibody that fuses human α-L-iduronidase (IDUA) and targets the human insulin receptor (HIR). Valanafusp alfa has brain penetrating properties, making it useful for research on mucopolysaccharidosis type I (MPS I) .

HY-P99759

*Nogapendekin alfa* (his tag)** IL-15N72D	Interleukin Related	Inflammation/Immunology Cancer
Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL)-15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept (HY-P99661) at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8 ⁺ T cells .

HY-112865

Octocog alfa ADVATE; BAY 81-8973; Kovaltry	Factor VIII	Cardiovascular Disease
Octocog alfa (ADVATE; BAY 81-8973; Kovaltry) is a standard half-length recombinant coagulation factor FVIII replacement therapy that also functions as a thrombin generation modulator. Octocog alfa regulates thrombin generation-related parameters in vitro and is used in studies related to severe hemophilia A .

HY-P99841

Dalutrafusp alfa AGEN-1423; GS-1423	CD73 TGF-β Receptor	Inflammation/Immunology Cancer
Dalutrafusp alfa (AGEN-1423; GS-1423) is a specific bifunctional antibody against CD73 and TGF-β, which is involved in the immunosuppressive pathway .

HY-P991067

Vensobafusp alfa KP-104	Complement System	Inflammation/Immunology
Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody directed against terminal complement protein C5 fused to the complement factor H 1-5 domain (FH1-5). Vensobafusp alfa shows anti-inflammatory and immunomodulatory activities. The isotype control for Vensobafusp alfa can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003) . .

HY-P3385

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

HY-P990088

Sotiburafusp alfa	VEGFR PD-1/PD-L1	Cardiovascular Disease
Sotiburafusp alfa is a bispecific fusion protein, which is a humanized VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) fused via the peptide linker ¹⁰¹GGSGGSGGSGGSGGS ¹¹⁵ to the N-terminus of the heavy chain (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain variant L352>A, L353>A. Sotiburafusp alfa also functions as a PD-L1 inhibitor and a VEGF inhibitor .

HY-P99694

Lepunafusp alfa JR-171	Transferrin Receptor	Neurological Disease
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I .

HY-P991676

Eflumenibep alfa DS-2325A	Kallikrein	Inflammation/Immunology
Eflumenibep alfa is a Kallikrein 5 inhibitor with anti-inflammatory activity. Eflumenibep alfa is a fusion protein that combines human SPINK2 with the human IgG1 Fc fragment at the C-terminus .

HY-P99769

Omfiloctocog alfa SCT-800	Factor VIII	Metabolic Disease
Omfiloctocog alfa (SCT-800) is a recombinant factor VIII (FVIII). FVIII is an essential blood coagulation protein and a key component of the fluid phase blood coagulation system. Omfiloctocog alfa can be used for the research of Hemophilia A .

HY-P99772

Onfekafusp alfa L19TNF	TNF Receptor	Cancer
Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research .

HY-P991678

Efpixileukin alfa XENP-27564; XMAB-27564	Interleukin Related	Inflammation/Immunology
Efpixileukin alfa is a fusion protein that combines human IL-2 variant fused at the C-terminus to human immunoglobulin G1 (IgG1) Fc fragment. Efpixileukin alfa is an immunomodulator .

HY-P991701

Mebarase alfa	NTPDase	Cancer
Mebarase alfa is a human monoclonal antibody targeting ENTPD1/CD39 for the study of sepsis-associated renal injury .

Cat. No.	상품명	Target	Research Area

HY-P10531

ALFA-tag	Peptides	Others
ALFA-tag is a small and stable α-helical structure composed of 15 amino acids. ALFA-tag is highly hydrophilic and can be placed at the N-terminus, C-terminus, or between two independently folded domains of the target protein without affecting the function of the protein. ALFA-tag is widely used as an epitope tag and is used for the detection and manipulation of proteins in living cells .

HY-P3385

Rilunermin alfa SCB-313	Drug Derivative Apoptosis	Cancer
Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .

Species:	Human (5) Mouse (2)
Tag:	SUMO (1) His (5) Tag Free (1) Fc (1)
Source:	HEK293 (4) CHO (2) E. coli (1)

Cat. No.	Compare	상품명	Species	Source	Image

HY-P7211

	IL-18BP Protein, Human (CHO) 2 Publications Verification rHuIL-18BP; Tadekinig-alfa; IL18BP	Human	CHO
	IL-18BP Protein, Human (CHO) Binding Protein (CHO-expressed) is a modulator of the Th1 cytokine response.

HY-P75841

	IL-18BP Protein, Mouse (HEK293, His) 5 Publications Verification Interleukin-18-binding protein; IL-18BP; Tadekinig-alfa	Mouse	HEK293
	IL-18BP protein regulates immune processes by binding to interleukin-18 (IL-18), inhibiting its activity. This interaction positions IL-18BP as a key inhibitor of the early TH1 cytokine response, emphasizing its role in immune modulation and potential contribution to regulating inflammatory responses. IL-18BP Protein, Mouse (HEK293, His) is the recombinant mouse-derived IL-18BP protein, expressed by HEK293 , with C-His labeled tag.

HY-P72575

	IL-18BP Protein, Human (HEK293, hFc) 1 Publications Verification Interleukin-18-binding protein; IL-18BP; Tadekinig-alfa	Human	HEK293
	IL-18BP Protein belongs to immunoglobulin superfamily that bind to IL-18 and inhibits its activity. IL-18BP Protein functions as an inhibitor of the Th1 cytokine response. IL-18BP Protein, Human (HEK293, hFc) is the recombinant human-derived IL-18BP protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72974

	DNase I Protein, Human (HEK293, His) 5 Publications Verification Deoxyribonuclease-1; DNase I; Dornase alfa; DNASE1; DNL1; DRNI	Human	HEK293
	The DNase I protein is a serum endonuclease secreted by a variety of exocrine and endocrine organs and expressed in non-hematopoietic tissues. It preferentially selects protein-free DNA, plays a key role in apoptosis-induced cell death, and inhibits actin polymerization by specifically binding to G-actin. DNase I Protein, Human (HEK293, His) is the recombinant human-derived DNase I protein, expressed by HEK293 , with C-His labeled tag.

HY-P73045

	Coagulation Factor VII/F7 Protein, Mouse (CHO, His) Coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Mouse	CHO
	Coagulation Factor VII (F7) protein lacks crucial conserved residue(s) needed for propagating feature annotation. Coagulation Factor VII/F7 Protein, Mouse (CHO, His) is the recombinant mouse-derived Coagulation Factor VII/F7 protein, expressed by CHO , with C-His labeled tag.

HY-P700565

	Coagulation factor VII/F7 Protein, Human (His-SUMO) Coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Human	E. coli
	Coagulation factor VII (F7) initiates the extrinsic pathway of blood coagulation. As a circulating zymogen, F7 is activated to F7a through proteolysis induced by factor Xa, factor XIIa, factor IXa, or thrombin. In the presence of tissue factor and calcium ions, F7a catalyzes limited proteolysis of factor X, converting it to factor Xa. F7a can also convert factor IX to factor IXa, emphasizing its pivotal role in coagulation cascades. Coagulation factor VII/F7 Protein, Human (His-SUMO) is the recombinant human-derived Coagulation factor VII/F7 protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.

HY-P74239

	Coagulation Factor VII/F7 Protein, Human (HEK293, His, solution) Coagulation factor VII; Eptacog alfa; F7; FVII coagulation protein; SPCA	Human	HEK293
	Coagulation factor VII (F7) initiates the extrinsic pathway of blood coagulation. As a circulating zymogen, F7 is activated to F7a through proteolysis induced by factor Xa, factor XIIa, factor IXa, or thrombin. In the presence of tissue factor and calcium ions, F7a catalyzes limited proteolysis of factor X, converting it to factor Xa. F7a can also convert factor IX to factor IXa, emphasizing its pivotal role in coagulation cascades. Coagulation Factor VII/F7 Protein, Human (HEK293, His, solution) is the recombinant human-derived Coagulation Factor VII/F7 protein, expressed by HEK293 , with C-His labeled tag.

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Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

Host:	Mouse (2) Rabbit (3)
Reactivity:	Human (5) Mouse (2) Rat (3)
Application:	IHC-P (3) ICC/IF (1) IF-Tissue (1) IP (1) WB (5) ELISA (1)
Isotype:	IgG (3) IgG1 (1)
Conjugation:	Non-conjugated (5)
Clonality:	Monoclonal (4) Recombinant (2)
Modification:	Unmodified (4)

Cat. No.	Compare	상품명	Application	Reactivity	Image

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	IL18BP Antibody (YA10029) is a Rabbit-derived and non-conjugated IgG Monoclonal, Recombinant antibody, targeting to IL18BP.

HY-P85579

	IL18BP Antibody (YA5271) I18BP_HUMAN; IL-18BP; IL18 BP; IL18 BPa; IL18BP; IL18BPa; Interleukin 18 binding protein; Interleukin-18-binding protein; MC51L 53L 54L homolog gene product; Tadekinig alfa; Tadekinig-alfa.	WB	Human
	IL18BP Antibody (YA5271) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to IL18BP.

HY-P82810

	BMP7 Antibody (YA2555) Bmp7; Bone morphogenetic protein 7; Eptotermin alfa; OP 1; Osteogenic protein 1	WB, IP	Human, Mouse, Rat
	BMP7 Antibody (YA2555) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to BMP7.

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	GAA Antibody (YA9716) 70 kDa lysosomal alpha-glucosidase, Acid alpha glucosidase, Acid maltase, Aglucosidase alfa, Alpha glucosidase, GAA, Glucosidase alpha acid (Pompe disease glycogen storage disease type II), Glucosidase alpha acid, Glucosidase alpha, LYAG	WB, IF-Tissue, IHC-P	Human
	GAA Antibody (YA9716) is a Rabbit-derived and non-conjugated IgG Recombinant,Monoclonal antibody, targeting to GAA.

HY-P85929

	Topoisomerase II alpha Antibody (YA5621) alpha isozyme; ATP hydrolyzing DNA topoisomerase II alfa; DNA gyrase; DNA topoisomerase; ATP hydrolyzing; DNA topoisomerase 2 alpha; DNA topoisomerase 2-alpha; DNA topoisomerase II 170 kD; DNA topoisomerase II alpha isozyme; DNA topoisomerase II; DNA Topoisomerase2; TOP 2A; TOP2; TOP2A; TOP2A_HUMAN; Topoisomerase DNA II alpha 170 kDa; TP2A	IHC-P, WB, ICC/IF, ELISA	Human, Mouse, Rat
	Topoisomerase II alpha Antibody (YA5621) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Topoisomerase II alpha.

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Reactivity
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Formulation
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 해외재고보유 - + 장바구니에 담기 견적 받기

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