Vatreptacog alfa
Vatreptacog alfa is a recombinant hFVIIa analog, differing from native FVIIa by three amino acid substitutions (V158D, E296V and M298Q) in the protease domain. Vatreptacog alfa exhibits enhanced tissue factor-independent enzymatic activity toward activated platelets. Vatreptacog alfa can be used in the research of hemophilia.
For research use only. We do not sell to patients.
- CAS No.: 897936-89-9
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Human
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 897936-89-9
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SMILES
[Vatreptacog alfa]
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Synonyms
NN-1731
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Vatreptacog alfa
- 897936-89-9
- NN-1731
- NN1731
- NN 1731
- Factor VIIa
- Drug Derivative
- tissue factor
- human factor VII knock-in transgenic mice
- immunoglobulin M subtype
- immunoglobulin G subtype
- neonatal recombinant factor VIIa-tolerized rats
- protease domain
- hemophilia a
- recombinant human factor VII
- hemophilia b
- activated platelets
- Inhibitor
- inhibitor
- inhibit