Bifikafusp alfa
Based on 1 Customer Validation
Bifikafusp alfa (L19-IL2) is an immunoresearch fusion protein consisting of human L19 antibodies fused to the human cytokine interleukin 2 (IL2).Bifikafusp alfa is specific to the EDB domain of fibronectin. Bifikafusp alfa has anticancer activity.
For research use only. We do not sell to patients.
- Purity: 96%
- CAS No.: 1957239-90-5
- Molecular Weight:84.058 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
scFv-heavy-kappa
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Female NMRI nude mice with MiaPaca-A2 xenografts[1]
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Dosage:1.43 and 4.29 MIU/kg
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Administration:Intraperitoneal injection; daily; for 10 days
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Result:Reduced tumor volume to 21.4% (1.43 MIU/kg) and 2.7% (4.29 MIU/kg) compared with control mice.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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scFv-heavy-kappa
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 1957239-90-5
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Appearance Liquid
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Molecular Weight 84.058 kDa
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Color Colorless to light yellow
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SMILES
[Bifikafusp alfa]
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Synonyms
L19-IL2
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (256 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)