Tabirafusp alfa
Based on 1 Customer Validation
Tabirafusp alfa (OG-2072, KSI-101) is a bispecific antibody trap fusion protein that inhibits IL-6 and VEGF. Tabirafusp alfa is a first-in-class, high-strength intravitreal biologic designed to target IL-6 mediated inflammation and VEGF-mediated vascular permeability in macular edema secondary to inflammation (MESI).
For research use only. We do not sell to patients.
- Purity : 98.08%
- CAS No.: 2839527-15-8
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Storage:Shipping with dry ice
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
Human IgG1 kappa
Recommend Isotype Controls
Species Reactivity
Human
IC50 & Target
IL-6[1]
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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IgG1-kappa-[2PROTEINS]2-in-VH_1cys_drug
Application
ELISA, FACS, Functional assay
Verified Bioactivity
Chemical Information
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CAS No. 2839527-15-8
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Tabirafusp alfa]
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Synonyms
OG-2072
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (256 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)