Zemlikafusp alfa
Based on 1 Customer Validation
Zemlikafusp alfa (IPH6501) is a tetra-specific NK cell engager that targets CD20, CD16a, NKp46 and carries an IL-2 variant. Zemlikafusp alfa (IPH6501) is used in research for the treatment of relapsed/refractory B-cell non-Hodgkin lymphoma.
For research use only. We do not sell to patients.
- Purity : 97.43%
- Molecular Weight:141.14 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Isotype
half-IgG1-(scFv-heavy-kappa)-IL2 / L-kappa-h-CH2-CH3
Species Reactivity
Human
Gene ID
Accession
P11836 & AAH64806
Target
CD20/MS4A1 & NCR1
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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half-IG G1 - (scFv - heavy - kappa) - IL2 / L-kappa-h-CH2-CH3
Application
ELISA, FACS, Functional assay
Verified Bioactivity
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Immobilized CD20/MS4A1 Protein, Human (HEK293, HY-P78543) can bind Zemlikafusp alfa. The ED50 for this effect is 582.5 ng/mL -
Immobilized NKp46/NCR1 Protein, Human (HEK293, HY-P70174) can bind Zemlikafusp alfa. The ED50 for this effect is 82.41 ng/mL.
Chemical Information
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Appearance Liquid
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Molecular Weight 141.14 kDa
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Color Colorless to light yellow
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SMILES
[Zemlikafusp alfa]
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Synonyms
IPH6501
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)