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Modakafusp alfa

(別名: TAK-573)
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Based on 1 Customer Validation

Modakafusp alfa (TAK-573) is a humanized, anti-CD38 IgG4 monoclonal antibody fused to 2 attenuated IFNα2b molecules, which delivers interferon-alpha to CD38-expressing cells. Modakafusp alfa has direct anti-proliferative activity on multiple myeloma (MM) cancer cells in vitro and induces robust and durable antitumor responses in MM xenograft tumor models. Modakafusp alfa in combination with anti-PD-1 antibodies induces immunomodulation and antitumor responses with good tolerance in mice.

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  • 純度 : 96.22%
  • CAS 番号: 2254522-19-3
  • 分子量:183.48 kDa
  • 保管条件:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Modakafusp alfa
  • Experimental Validation Results for Modakafusp alfa
  • Experimental Validation Results for Modakafusp alfa
  • Modakafusp alfa Chemical Structure
    Modakafusp alfa 構造式
CAS 番号: 2254522-19-3
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Modakafusp alfa can bind Human CD38 Protein (ECD, His Tag). The EC50 for this effect is 2.553 ng/mL.

  • 1/16

    Immobilized Modakafusp alfa can bind Anti-Interferon alpha 2/IFNA2 Antibody. The EC50 for this effect is 14.45 ng/mL.

  • Modakafusp alfa Chemical Structure
    1/16
  • Modakafusp alfa
  • Immobilized Modakafusp alfa can bind Human CD38 Protein (ECD, His Tag). The EC50 for this effect is 2.553 ng/mL.
  • Immobilized Modakafusp alfa can bind Anti-Interferon alpha 2/IFNA2 Antibody. The EC50 for this effect is 14.45 ng/mL.