Efbalropendekin alfa
Based on 1 Customer Validation
Efbalropendekin Alfa (XmAb24306) is an IL-15/IL-15 receptor alpha complex fused to a heterodimeric Fc domain (IL15/IL15Rα-Fc). Efbalropendekin Alfa increases direct and antibody-dependent cellular cytotoxicity (ADCC)-mediated human natural killer (NK) cell cytotoxicity in vitro.
For research use only. We do not sell to patients.
- Purity: 97.17%
- CAS No.: 2736449-62-8
- Molecular Weight:72.62 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IL15RA
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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FPIA_[PROTEIN]2-FC
ELISA, FACS, Functional assay
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Immobilized IL-15R alpha & IL-15 Protein, Human (HEK293, HY-P77699) can bind Efbalropendekin alfa. The ED50 for this effect is 299 ng/mL.
Chemical Information
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CAS No. 2736449-62-8
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Molecular Weight 72.62 kDa
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Synonyms
XmAb24306
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)