Lepunafusp alfa
Lepunafusp alfa (JR-171) is a BBB-penetrable fusion protein consisting of J-Brain Cargo and IDUA (a lysosomal enzyme, α-L-iduronidase). Lepunafusp alfa can reduce concentration of heparan sulfate (HS) and dermatan sulfate (DS). Lepunafusp alfa can be used for research of mucopolysaccharidosis type I.
For research use only. We do not sell to patients.
- CAS No.: 2396411-71-3
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
fused with Homo sapiens IDUA (iduronidase, alpha-L-) isoform 1, Pr27-653 (1:2)
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
-
F(ab')2-G1-kappa
2-G1-kappa-PROT.png)
ELISA, FACS, Functional assay
Chemical Information
-
CAS No. 2396411-71-3
-
SMILES
[Lepunafusp alfa]
-
Synonyms
JR-171
-
Formulation
Please refer to the lot-specific COA for specific buffer information.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Lepunafusp alfa Related Classifications
HY-P99694 Related Classifications
Powered by Bioz