Search Result

Results for "

Rp-ATPαS tetrasodium

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adenylate Cyclase (3) Amino Acid Derivatives (1) Apoptosis (2) Arf Family GTPase (1) Bacterial (7) Biochemical Assay Reagents (14) Calcium Channel (4) CaMK (1) Caspase (1) CHIKV (1) DNA Alkylator/Crosslinker (1) DNA Stain (1) DNA/RNA Synthesis (10) Drug Derivative (7) Drug Isomer (1) Drug Metabolite (1) EBV (1) Endogenous Metabolite (8) Enterovirus (1) Environmental Pollutants (3) Eukaryotic Initiation Factor (eIF) (1) Ferroptosis (2) Fluorescent Dye (8) Glutamate Dehydrogenase (GLDH) (1) Guanylate Cyclase (1) HBV (1) HCV (2) Histone Acetyltransferase (1) HIV (7) HIV Protease (1) iGluR (1) MicroRNA (1) Microtubule/Tubulin (1) MMP (1) MOFs (5) Na+/Ca2+ Exchanger (1) Nucleoside Antimetabolite/Analog (29) P2X Receptor (6) P2Y Receptor (18) PARP (1) Phospholipase (2) PINK1/Parkin (1) Potassium Channel (1) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (3) Reverse Transcriptase (2) SARS-CoV (2) SOD (1) Toll-like Receptor (TLR) (1) Topoisomerase (2) Wnt (1)
By Research Areas:	Cancer (18) Cardiovascular Disease (11) Infection (24) Inflammation/Immunology (15) Metabolic Disease (19) Neurological Disease (10)
Click Chemistry:	Azide (1) Alkynes (1)
Oligonucleotides:	Nucleotide Analogs (3) Nucleoside Analogs (1) Adenine Nucleotide (1)

125

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-F0003

*NADPH tetrasodium* salt** 15+ Cited Publications	Ferroptosis Endogenous Metabolite	Metabolic Disease Cancer
NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication .

HY-19638A

Cangrelor tetrasodium 4 Publications Verification AR-C69931MX tetrasodium	P2Y Receptor	Cardiovascular Disease Inflammation/Immunology
Cangrelor tetrasodium, an adenosine triphosphate analogue, is a reversible and selective platelet P2Y12 antagonist, with prompt and potent antiplatelet effects. Cangrelor tetrasodium directly blocks adenosine diphosphate (ADP)-induced activation and aggregation of platelets. Cangrelor tetrasodium is also a nonspecific GPR17 antagonist .

HY-100168A

BAPTA tetrasodium Maximum Cited Publications 36 Publications Verification	Phospholipase	Others
BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium has high selectivity against magnesium and calcium. BAPTA can also inhibit phospholipase C activity independently of their role as Ca ²⁺ chelators .

HY-B0606

Diquafosol tetrasodium 5 Publications Verification INS365	P2Y Receptor	Inflammation/Immunology
Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease.

HY-141466A

Crotonyl-CoA tetrasodium	Endogenous Metabolite Histone Acetyltransferase	Infection Metabolic Disease Inflammation/Immunology
Crotonyl-CoA tetrasodium, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA tetrasodium is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA tetrasodium acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA tetrasodium regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA tetrasodium serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA tetrasodium can be used for the research of LPS-induced inflammatory response .

HY-Y1885

Tetrasodium pyrophosphate	Biochemical Assay Reagents Bacterial SARS-CoV	Infection
Tetrasodium pyrophosphate is a water-soluble inorganic salt commonly used as a buffering agent, emulsifier, and sequestrant. Tetrasodium pyrophosphate is an antimicrobial agent that can reduce microbial colonization. Tetrasodium pyrophosphate blocks IPP translocation, enhances astaxanthin, phenol, flavonoid, and H₂O₂ levels, activates PAL and DPPH scavenging activity. Tetrasodium pyrophosphate can be used for the research of alleviating symptoms post COVID-19 .

HY-105070A

Eritoran tetrasodium E5564	EBV Toll-like Receptor (TLR)	Infection Inflammation/Immunology
Eritoran tetrasodium (E5564) is a Toll-like receptor 4 (TLR4) antagonist. Eritoran tetrasodium protects mice against lethal influenza virus infection, such as Ebola virus (EBOV), Marburg virus (MARV). Eritoran tetrasodium decreases the level of granulocytosis, may alleviate the severity of the "cytokine storm". Eritoran tetrasodium inhibits pathogenesis of filovirus infection. Eritoran tetrasodium has anti-inflammatory activity .

HY-D0861A

EGTA tetrasodium 20+ Cited Publications	Biochemical Assay Reagents	Inflammation/Immunology
EGTA tetrasodium is a cell-impermeant specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca ²⁺ over Mg ²⁺ (Mg ²⁺ K_d 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages .

HY-W134072

Tetrasodium glutamate diacetate (46% in water)	Environmental Pollutants Endogenous Metabolite Biochemical Assay Reagents Bacterial	Infection Others
Tetrasodium glutamate diacetate (46% in water) is a biodegradable chelating agent that enhances antibacterial efficacy. Tetrasodium glutamate diacetate (46% in water) improves the antibacterial performance of multifunctional additives in cosmetic formulations. Tetrasodium glutamate diacetate (46% in water) acts as a chelating agent in cosmetic formulations .

HY-103317A

NAADP tetrasodium	Calcium Channel	Cardiovascular Disease Cancer
NAADP tetrasodium is a second messenger. NAADP tetrasodium releases Ca ²⁺ from acidic endosomes and lysosomes. NAADP tetrasodium can be used to study cancer (such as oral squamous cell carcinoma, malignant melanoma) and angiogenesis-related diseases .

HY-108675

PPNDS tetrasodium	MMP P2X Receptor	Infection Cancer
PPNDS tetrasodium is a selective and competitive meprin β inhibitor (IC₅₀: 80 nM, K_i: 8 nM), and also inhibits ADAM10 (IC₅₀: 1.2 μM). PPNDS tetrasodium is also a P2X1 receptor antagonist. PPNDS is an agonist for the ATP receptor of Paramecium. PPNDS tetrasodium potently inhibits polymerases from viruses. PPNDS tetrasodium can be used in the research of infection and cancers .

HY-131596B

*Emtricitabine triphosphate tetrasodium* salt** (-)-Emtricitabine triphosphate tetrasodium salt	Reverse Transcriptase HBV HIV	Infection
Emtricitabine triphosphate tetrasodium salt is the tetrasodium salt form of Emtricitabine triphosphate (HY-131596). However，Emtricitabine triphosphate ((-)-Emtricitabine triphosphate) is the phosphorylated anabolite of Emtricitabine (HY-17427)，a nucleoside reverse transcriptase inhibitor，targeting to HIV and HBV .

HY-W110883

*Xylenol orange tetrasodium* salt, IND** 1 Publications Verification	Biochemical Assay Reagents	Others
Xylenol Orange (tetrasodium), metal indicator, AR is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-12294A

*PEAQX tetrasodium* hydrate** 5+ Cited Publications NVP-AAM077 tetrasodium hydrate	Apoptosis Caspase iGluR	Neurological Disease
PEAQX tetrasodium hydrate (NVP-AAM077 tetrasodium hydrate) is a tetrasodium hydrate of PEAQX (HY-12294). PEAQX tetrasodium hydrate is an orally active and selective NMDA antagonist, with IC₅₀ values of 270 nM and 29.6 μM for hNMDAR 1A/2A and hNMDAR 1A/2B, respectively. PEAQX tetrasodium hydrate can promote the activation of caspase-3 and induce cell apoptosis in cortical striatal slice cultures .

HY-F0003R

*NADPH tetrasodium* salt (Standard)**	Reference Standards Ferroptosis Endogenous Metabolite	Metabolic Disease Cancer
NADPH tetrasodium salt (Standard) is the analytical standard of NADPH tetrasodium salt (HY-F0003). This product is intended for research and analytical applications. NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication.

HY-134398A

Kinetin triphosphate tetrasodium 6-Fu-ATP tetrasodium; KTP tetrasodium	PINK1/Parkin	Neurological Disease Cancer
Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research .

HY-115581A

Thymidine 3',5'-diphosphate tetrasodium Deoxythymidine 3′,5′-diphosphate tetrasodium; pdTp tetrasodium	Apoptosis MicroRNA	Cancer
Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the MicroRNA regulatory complex RISC subunit) and [3,5- ²H₂] tyrosyl nuclease. Thymidine 3',5'-diphosphate tetrasodium has anti-tumor activity and can also be used as a catalyst in biochemical reactions .

HY-101308A

*MRS2179 tetrasodium* hydrate** 2 Publications Verification	P2Y Receptor	Cardiovascular Disease
MRS2179 tetrasodium hydrate is a competitive P2Y1 receptor antagonist, with a K_b of 102 nM and a pA₂ of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium hydrate is selective for P2Y1 over P2X1 (IC₅₀=1.15 µM), P2X3 (12.9 µM), P2X2, P2X4, P2Y2, P2Y4, and P2Y6 receptors . MRS2179 tetrasodium hydrate inhibits platelet aggregation .

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium	Fluorescent Dye	Others
Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium acts as a water-soluble fluorescent dye for fluorescence quenching assays monitoring gramicidin ion-channel activity .

HY-Y0682B

Ethylenediaminetetraacetic acid tetrasodium 20+ Cited Publications EDTA tetrasodium	Environmental Pollutants Biochemical Assay Reagents Bacterial SOD	Cardiovascular Disease Neurological Disease Cancer
Ethylenediaminetetraacetic acid (EDTA) tetrasodium is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid tetrasodium has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid tetrasodium decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid tetrasodium can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid tetrasodium can be used for coronary artery disease and neural system disease research .

HY-136647

8-Bromoadenosine 5'-triphosphate tetrasodium 8-Br-ATP tetrasodium	Drug Derivative	Others
8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is an ATP analogue. ATP is a central component of energy storage and metabolism in vivo .

HY-108649A

*MRS2768 tetrasodium* salt**	P2Y Receptor	Cardiovascular Disease
MRS2768 tetrasodium salt is a moderately potent and selective P2Y2 receptor agonist. MRS2768 tetrasodium salt has a protective effect on cardiomyocytes from ischemic damage in vivo and in vitro .

HY-W035051

TSPP tetrasodium	MOFs Fluorescent Dye	Infection Cancer
TSPP tetrasodium is a photosensitizer that has shown impressive effects in in vivo regression of cancer and microorganism infections (Ex: 413 nm, Em: 640 nm) .

HY-139579A

Pafolacianine tetrasodium OTL 38 tetrasodium	Fluorescent Dye	Cancer
Pafolacianine tetrasodium (OTL 38 tetrasodium) is a fluorescent imaging agent made of near-infrared dye used in detecting tumor lesions during surgical procedures. Pafolacianine tetrasodium excites at 774 to 775 nm and emits at 794 to 796 nm .

HY-W105699

*EDTA tetrasodium* tetrahydrate** Ethylenediaminetetraacetic acid tetrasodium tetrahydrate	Environmental Pollutants Biochemical Assay Reagents	Others
EDTA tetrasodium tetrahydrate is a metal chelator (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. EDTA tetrasodium tetrahydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA tetrasodium tetrahydrate can also decrease the formation of disulfide bonds .

HY-131598C

6-Thio-GTP tetrasodium 6-Thioguanosine-5'-triphosphate tetrasodium	Ras	Inflammation/Immunology
6-Thio-GTP (tetrasodium) is a Vav1-Rac inhibitor. 6-Thio-GTP (tetrasodium) inhibits TCR-stimulated T cell proliferation and CD28-mediated T cell survival. 6-Thio-GTP (tetrasodium) has an immunosuppressive effect in a mouse cardiac allograft transplant model and prolongs cardiac allograft survival .

HY-134361

ATP-γ-S tetrasodium	P2Y Receptor Eukaryotic Initiation Factor (eIF)	Neurological Disease Metabolic Disease Inflammation/Immunology
ATP-γ-S (tetrasodium) is a P2Y11 receptor agonist, an antioxidant and a neuroprotective agent. ATP-γ-S (tetrasodium) can be used as a substrate for the nucleotide hydrolysis and RNA unwinding activities of eukaryotic translation initiation factor eIF4A. ATP-γ-S (tetrasodium) is active in ATP hydrolysis .

HY-D1686B

Biotin-16-UTP tetrasodium	DNA Stain	Others
Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .

HY-173537

*D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium* salt** Ins(1,2,4,5)P4 tetrasodium salt; 1,2,4,5-IP4 tetrasodium salt	Calcium Channel	Neurological Disease
D-myo-Inositol-1,2,4,5-tetraphosphate (DL-Ins-(1,2,4,5)P4) tetrasodium is raracemic regioisomer of myo-inositol tetrakisphosphates (IP4s). D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium is an Ins(1,4,5)P3 receptor agonist with a K_i of 11 nM. D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium induces Ca ²⁺ mobilization with an EC₅₀ value of 0.22 μM in CHO cells .

HY-138561B

EFdA-TP tetrasodium	Reverse Transcriptase DNA/RNA Synthesis HIV	Infection
EFdA-TP tetrasodium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms . EFdA-TP (tetrasodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-139165A

AT-9010 tetrasodium 1 Publications Verification	SARS-CoV	Infection
AT-9010 tetrasodium, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 tetrasodium can inhibit SARS-CoV-2 replication .

HY-131800A

*3'-NH2-ATP tetrasodium, 100 mM Solution*	Nucleoside Antimetabolite/Analog	Others
3'-NH2-ATP tetrasodium is an ATP substitute created by inserting an amino acid at the C3 position of ATP. 3'-NH2-ATP tetrasodium catalyzes RNA synthesis in the presence of RNA polymerase .

HY-135867A

NHC-triphosphate tetrasodium	CHIKV Endogenous Metabolite Enterovirus HCV Topoisomerase	Infection
NHC-triphosphate tetrasodium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form . NHC-triphosphate tetrasodium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA .

HY-W127722

Direct Red 75 tetrasodium	Biochemical Assay Reagents	Others
Direct Red 75 tetrasodium salt is an azo dye.

HY-101308

MRS2179 tetrasodium	P2Y Receptor	Cardiovascular Disease
MRS2179 tetrasodium is a competitive P2Y1 receptor antagonist, with a K_b of 102 nM and a pA₂ of 6.99 for turkey P2Y1 receptor. MRS2179 tetrasodium is selective for P2Y1 over P2X1 (IC₅₀=1.15 µM), P2X3 (12.9 µM), P2X2, P2X4, P2Y2, P2Y4, and P2Y6 receptors . MRS2179 tetrasodium inhibits platelet aggregation .

HY-141627

Heparin disaccharide I-S tetrasodium	Biochemical Assay Reagents	Others
Heparin carbohydrate IS tetrasodium is the major disaccharide produced by heparinases I and II from heparin.

HY-106950S1

*Fosfructose-13C6 tetrasodium* hydrate** Diphosphofructose-13C6 tetrasodium hydrate; Esafosfan-13C6 tetrasodium hydrate; FDP-13C6 tetrasodium hydrate	Endogenous Metabolite	Cardiovascular Disease
Fosfructose- ¹³C₆ (tetrasodium hydrate) is the ¹³C labeled Fosfructose (HY-106950). Fosfructose is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma .

HY-19638AR

*Cangrelor tetrasodium* (Standard)** AR-C69931MX tetrasodium (Standard)	P2Y Receptor Reference Standards	Cardiovascular Disease Inflammation/Immunology
Cangrelor (tetrasodium) (Standard) is the analytical standard of Cangrelor (tetrasodium). This product is intended for research and analytical applications. Cangrelor tetrasodium, an adenosine triphosphate analogue, is a reversible and selective platelet P2Y12 antagonist, with prompt and potent antiplatelet effects. Cangrelor tetrasodium directly blocks adenosine diphosphate (ADP)-induced activation and aggregation of platelets. Cangrelor tetrasodium is also a nonspecific GPR17 antagonist .

HY-134274A

8-Br-GTP tetrasodium 8-Bromoguanosine-5'-triphosphate tetrasodium	Bacterial	Metabolic Disease
8-Br-GTP (tetrasodium) (8-Bromoguanosine-5'-triphosphate (tetrasodium)) is a derivative of the energy substrate – GTP, for protein synthesis and gluconeogenesis. 8-Br-GTP (tetrasodium) inhibits the E. coli GTPase FtsZ with a K_i of 31.8 μM. 8-Br-GTP (tetrasodium) promotes the assembly of porcine brain microtubules .

HY-131601A

3'-Fluorothymidine-5'-triphosphate tetrasodium 3'-FdTTP tetrasodium	DNA/RNA Synthesis Drug Derivative	Others
3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP (HY-138615) analog. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits the T4 DNA polymerases competitively with dTTP. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits DNA synthesis by T4 wild-type, L98 and CB121 DNA polymerase .

HY-137613C

Rp-TTPαS tetrasodium	HIV	Infection
Rp-TTPαS (tetrasodium) is the Rp-isomer of TTPαS (tetrasodium). Rp-TTPαS (tetrasodium) incorporate with HIV-1 reverse transcriptase (HIV-1 RT) with HIV-1 RT with large phosphorothioate elemental effects .

HY-W110904

Methylthymol blue tetrasodium	Fluorescent Dye	Others
Methylthymol blue tetrasodium is a metallochromic indicator dye and can be used for determination of sulfate and calcium .

HY-110092

PSB-1114 tetrasodium	P2Y Receptor	Metabolic Disease
PSB-1114 tetrasodium is a potent, enzymatically stable, and subtype-selective P2Y₂ receptor agonist with an EC₅₀ of 134 nM. PSB-1114 tetrasodium displays >50-fold selectivity versus the P2Y₄ (EC₅₀ of 9.3 μM) and P2Y₆ (EC₅₀ of 7.0 μM) receptors .

HY-108650

2-Thio-UTP tetrasodium 2-Thiouridine 5′-triphosphate tetrasodium	P2Y Receptor	Cancer
2-Thio-UTP tetrasodium is a potent P2Y₂, P2Y₄ and P2Y₆ agonist, which an be used for the research of cancer .

HY-107372D

Uridine triphosphate tetrasodium UTP tetrasodium; Uridine 5'-triphosphate tetrasodium	Biochemical Assay Reagents	Cardiovascular Disease
Uridine triphosphate (tetrasodium) (UTP (tetrasodium)) is released during cardiac ischemia. Uridine triphosphate (tetrasodium) belongs to a family of extracellular nucleotide signaling molecules. Uridine triphosphate (tetrasodium) can stimulate vasodilation, automaticity in ventricular myocytes and release tussue-quantitative activator (t-PA). Uridine triphosphate (tetrasodium)-induced t-PA release can dissolve the thrombus in myocardial infarction .

HY-137693A

ddTTPαS tetrasodium	Nucleoside Antimetabolite/Analog	Others
ddTTPαS tetrasodium is a sulfur-containing nucleoside triphosphate derivative. ddTTPαS tetrasodium can be used for chain extension in PCR assays .

HY-100168AR

*BAPTA tetrasodium* (Standard)**	Reference Standards Phospholipase	Others
BAPTA tetrasodium (Standard) is the analytical standard of BAPTA tetrasodium. This product is intended for research and analytical applications. BAPTA tetrasodium is a selective and cell-impermeant chelator for calcium. BAPTA tetrasodium, as calcium indicator, has high selectivity against magnesium and calcium. BAPTA tetrasodium is widely used as an intracellular buffer for investigating the effects of Ca ²⁺ release from intracellular stores or influx via Ca ²⁺-permeable channels in the plasma membrane. BAPTA tetrasodium can also inhibit phospholipase C activity independently of their role as Ca ²⁺ chelators .

HY-16146

Combretastatin A-1 phosphate tetrasodium OXi-4503 tetrasodium	Wnt Microtubule/Tubulin	Cancer
Combretastatin A-1 phosphate (OXi-4503) tetrasodium, a proagent of Combretastatin A-1, is a microtubule polymerization inhibitor that binds to the colchicine-binding site of tubulin. Combretastatin A-1 phosphate tetrasodium inhibits the Wnt/β-catenin pathway through tubulin depolymerization mediated AKT deactivation. Combretastatin A-1 phosphate tetrasodium exhibits anti-tumor and anti-vascular effects .

HY-101077

Iso-PPADS tetrasodium	P2X Receptor	Inflammation/Immunology
Iso-PPADS tetrasodium is a P2X-purinoceptor antagonist. Iso-PPADS tetrasodium inhibits P2X1 and P2X3 receptor with IC₅₀s of 43 nM and 84 nM. Iso-PPADS tetrasodium is protective against ventilator-induced brain injury (VIBI) .

HY-137618A

Sp-dGTPαS tetrasodium	Nucleoside Antimetabolite/Analog	Infection
Sp-dGTPαS tetrasodium is a sulfur-containing isomer of dGTP (HY-138616). Sp-dGTPαS tetrasodium inhibits SAMHD1 triphosphohydrolase activity with a K_i of 820 nM .

Cat. No.	Product Name	Type

HY-W110883

*Xylenol orange tetrasodium* salt, IND** 1 Publications Verification	Fluorescent Dyes
Xylenol Orange (tetrasodium), metal indicator, AR is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-D0142

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium

Fluorescent Dyes

Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium is a fluorescent dye and pH indicator, also as a ligand of multifunctional metal-organic framework. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium has been used to detect CO₂ release. Pyrene-1,3,6,8-tetrasulfonic acid tetrasodium acts as a water-soluble fluorescent dye for fluorescence quenching assays monitoring gramicidin ion-channel activity .

HY-D1686B

Biotin-16-UTP tetrasodium	Fluorescent Dyes
Biotin-16-UTP tetrasodium is an active substrate for RNA polymerase. Biotin-16-UTP tetrasodium can replace UTP in the in vitro transcription reaction for RNA labeling .

HY-W127722

Direct Red 75 tetrasodium	Fluorescent Dyes
Direct Red 75 tetrasodium salt is an azo dye.

HY-W110904

Methylthymol blue tetrasodium	Fluorescent Dyes
Methylthymol blue tetrasodium is a metallochromic indicator dye and can be used for determination of sulfate and calcium .

HY-W127725

Thymolphthalexon tetrasodium

Fluorescent Dyes

Thymolphthalexon (tetrasodium) is an organic compound commonly used as a reagent in biochemical assays. It belongs to the family of thioxanthone derivatives and has strong antioxidant properties. Thymolphthalexon has several applications in the study of free radical response, oxidative stress, and aging. In addition, it can be used as a photosensitizer in photodynamic therapy for the improvement of cancer and other diseases.

Cat. No.	Product Name	Type

HY-Y1885

Tetrasodium pyrophosphate

Biochemical Assay Reagents

Tetrasodium pyrophosphate is a water-soluble inorganic salt commonly used as a buffering agent, emulsifier, and sequestrant. Tetrasodium pyrophosphate is an antimicrobial agent that can reduce microbial colonization. Tetrasodium pyrophosphate blocks IPP translocation, enhances astaxanthin, phenol, flavonoid, and H₂O₂ levels, activates PAL and DPPH scavenging activity. Tetrasodium pyrophosphate can be used for the research of alleviating symptoms post COVID-19 .

HY-D0861A

EGTA tetrasodium 20+ Cited Publications	Biochemical Assay Reagents
EGTA tetrasodium is a cell-impermeant specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (K_d) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca ²⁺ over Mg ²⁺ (Mg ²⁺ K_d 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages .

HY-W035051

TSPP tetrasodium	Biochemical Assay Reagents
TSPP tetrasodium is a photosensitizer that has shown impressive effects in in vivo regression of cancer and microorganism infections (Ex: 413 nm, Em: 640 nm) .

HY-131800A

*3'-NH2-ATP tetrasodium, 100 mM Solution*	Biochemical Assay Reagents
3'-NH2-ATP tetrasodium is an ATP substitute created by inserting an amino acid at the C3 position of ATP. 3'-NH2-ATP tetrasodium catalyzes RNA synthesis in the presence of RNA polymerase .

HY-141627

Heparin disaccharide I-S tetrasodium	Biochemical Assay Reagents
Heparin carbohydrate IS tetrasodium is the major disaccharide produced by heparinases I and II from heparin.

HY-131787A

2-Amino-ATP tetrasodium	Biochemical Assay Reagents
2-Amino-ATP tetrasodium is an ATP substitute produced by inserting an amino acid at the C2 position of ATP .

HY-131801A

3'-NH2-GTP tetrasodium	Biochemical Assay Reagents
3'-NH2-GTP tetrasodium is a substitute for GTP, produced by inserting an amino acid into the C3 position of GTP .

HY-167231

Neocarraoctaose 41,43,45,47-tetrasulfate tetrasodium

Biochemical Assay Reagents

Neocarraoctaose 41,43,45,47-tetrasulfate (tetrasodium) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-135867A

NHC-triphosphate tetrasodium	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	CHIKV Endogenous Metabolite Enterovirus HCV Topoisomerase
NHC-triphosphate tetrasodium is an active phosphorylated intracellular metabolite of β-d-N4-Hydroxycytidine (NHC) (HY-125033) as a triphosphate form . NHC-triphosphate tetrasodium is a weak alternative substrate for the viral polymerase and can be incorporated into HCV replicon RNA .

HY-N15978

18:1-12:0 Biotin PIP3 tetrasodium	Lipid	Biochemical Assay Reagents
18:1-12:0 Biotin PIP3 tetrasodium is a biotinylated lipid.

HY-134313A

8-NH2-ATP tetrasodium 8-Aminoadenosine-5'-O-triphosphate tetrasodium	Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	DNA/RNA Synthesis Endogenous Metabolite
8-NH2-ATP tetrasodium, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado tetrasodium induces apoptosis-related cleavage of poly (ADP-ribose) polymerase .

Cat. No.	Product Name	Chemical Structure

HY-106950S1

*Fosfructose-13C6 tetrasodium* hydrate**
Fosfructose- ¹³C₆ (tetrasodium hydrate) is the ¹³C labeled Fosfructose (HY-106950). Fosfructose is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma .

Cat. No.	Product Name		Classification

HY-138561B

EFdA-TP tetrasodium		Alkynes
EFdA-TP tetrasodium is a potent nucleoside reverse transcriptase (RT) inhibitor. EFdA-TP tetrasodium inhibits RT-catalyzed DNA synthesis as an effective immediate or delayed chain terminator (ICT or DCT). EFdA-TP tetrasodium inhibits HIV-1 RT with multiple mechanisms . EFdA-TP (tetrasodium) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-134320A

8-Azido-ATP tetrasodium 8-Azidoadenosine 5'-triphosphate tetrasodium; 8-N3-ATP tetrasodium		Azide
8-Azido-ATP (8-Azidoadenosine 5'-triphosphate) tetrasodium, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase. 8-Azido-ATP tetrasodium is a click chemistry reagent that contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. 8-Azido-ATP tetrasodium can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .

Cat. No.	Product Name		Classification

HY-F0003

*NADPH tetrasodium* salt** 15+ Cited Publications		Nucleotide Analogs
NADPH tetrasodium salt functions as an important cofactor in a variety of metabolic and biosynthetic pathways. NADPH tetrasodium salt is an endogenous inhibitor of ferroptosis. NADPH tetrasodium salt plays a vital role in the biosynthesis of agents, chiral alcohols, fatty acids and biopolymers, while also being required for lipid biosynthesis, biomass formation, and cell replication .

HY-136647

8-Bromoadenosine 5'-triphosphate tetrasodium 8-Br-ATP tetrasodium		Nucleotide Analogs Adenine Nucleotide
8-Bromoadenosine 5'-triphosphate tetrasodium (8-Br-ATP tetrasodium) is an ATP analogue. ATP is a central component of energy storage and metabolism in vivo .

HY-137626B

Rp-ATPαS		Nucleoside Analogs Nucleotide Analogs
Rp-ATPαS is a monomeric raw material that can be used for nucleic acid synthesis.

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Rp-ATPαS tetrasodium

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Natural
Products