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  4. 3'-Fluorothymidine-5'-triphosphate tetrasodium

3'-Fluorothymidine-5'-triphosphate tetrasodium  (Synonyms: 3'-FdTTP tetrasodium)

Cat. No.: HY-131601A Purity: 99.94%
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Handling Instructions Technical Support

3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP (HY-138615) analog. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits the T4 DNA polymerases competitively with dTTP. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits DNA synthesis by T4 wild-type, L98 and CB121 DNA polymerase.

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3'-Fluorothymidine-5'-triphosphate tetrasodium

3'-Fluorothymidine-5'-triphosphate tetrasodium Chemical Structure

CAS No. : 1443116-39-9

Size Price Stock Quantity
Solvent
5.721 mg (100 mM * 100 μL in Water) In-stock
Solvent
28.605 mg (100 mM * 500 μL in Water) In-stock
Solvent
57.21 mg (100 mM * 1 mL in Water) In-stock

* Please select Quantity before adding items.

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3'-Fluorothymidine-5'-triphosphate tetrasodium Related Antibodies

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Description

3'-Fluorothymidine-5'-triphosphate tetrasodium (3'-FdTTP tetrasodium) is a dTTP (HY-138615) analog. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits the T4 DNA polymerases competitively with dTTP. 3'-Fluorothymidine-5'-triphosphate tetrasodium inhibits DNA synthesis by T4 wild-type, L98 and CB121 DNA polymerase[1][2].

IC50 & Target

DNA Polymerase

 

Molecular Weight

572.09

Formula

C10H12FN2Na4O13P3
CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=P(O[Na])(O[Na])OP(OP(OC[C@@H]1[C@@H](F)C[C@H](N(C=C(C(N2)=O)C)C2=O)O1)(O[Na])=O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (87.40 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7480 mL 8.7399 mL 17.4798 mL
5 mM 0.3496 mL 1.7480 mL 3.4960 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7480 mL 8.7399 mL 17.4798 mL 43.6994 mL
5 mM 0.3496 mL 1.7480 mL 3.4960 mL 8.7399 mL
10 mM 0.1748 mL 0.8740 mL 1.7480 mL 4.3699 mL
15 mM 0.1165 mL 0.5827 mL 1.1653 mL 2.9133 mL
20 mM 0.0874 mL 0.4370 mL 0.8740 mL 2.1850 mL
25 mM 0.0699 mL 0.3496 mL 0.6992 mL 1.7480 mL
30 mM 0.0583 mL 0.2913 mL 0.5827 mL 1.4566 mL
40 mM 0.0437 mL 0.2185 mL 0.4370 mL 1.0925 mL
50 mM 0.0350 mL 0.1748 mL 0.3496 mL 0.8740 mL
60 mM 0.0291 mL 0.1457 mL 0.2913 mL 0.7283 mL
80 mM 0.0218 mL 0.1092 mL 0.2185 mL 0.5462 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3'-Fluorothymidine-5'-triphosphate tetrasodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3'-Fluorothymidine-5'-triphosphate tetrasodium1443116-39-93'-FdTTP tetrasodiumDNA/RNA SynthesisDrug DerivativeDrug derivativeInhibitorinhibitorinhibit

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