2-Methylthio-ATP tetrasodium

Name: 2-Methylthio-ATP tetrasodium
Brand: MedChemExpress
SKU: HY-101370
Rating: 4.5 (1 reviews)

Cat. No.: HY-101370 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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2-Methylthio-ATP tetrasodium is a non-specific P2-receptor agonist. 2-Methylthio-ATP tetrasodium causes noncompetitive inhibition of ADP-induced human platelet aggregation.

For research use only. We do not sell to patients.

2-Methylthio-ATP tetrasodium Chemical Structure

CAS No. : 100020-57-3

Size	Price	Stock	Quantity
1 mg	USD 220	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

2-Methylthio-ATP tetrasodium is a non-specific P2-receptor agonist. 2-Methylthio-ATP tetrasodium causes noncompetitive inhibition of ADP-induced human platelet aggregation^[1].

Molecular Weight

641.20

Formula

C₁₁H₁₄N₅Na₄O₁₃P₃S

CAS No.

100020-57-3

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]1O)[C@](O[C@@H]1CO[P](O[P](O[P](O[Na])(O[Na])=O)(O[Na])=O)(O[Na])=O)([H])N2C3=NC(SC)=NC(N)=C3N=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (77.98 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5596 mL	7.7979 mL	15.5958 mL
5 mM	0.3119 mL	1.5596 mL	3.1192 mL
10 mM	0.1560 mL	0.7798 mL	1.5596 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

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Data Sheet (273 KB) SDS (252 KB)

COA (251 KB)

Handling Instructions (2659 KB)

References

[1]. N. J. Cusack, et al. Specific but noncompetitive inhibition by 2-alkylthio analogues of adenosine 5'-monophosphate and adenosine 5'-triphosphate of human platelet aggregation induced by adenosine 5'-diphosphate. Br J Pharmacol. 1982 Feb; 75(2): 397–400. [Content Brief]

[2]. S G Hamilton, et al. The effects of inflammation and inflammatory mediators on nociceptive behaviour induced by ATP analogues in the rat. Br J Pharmacol. 1999 Jan;126(1):326-32. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.5596 mL	7.7979 mL	15.5958 mL	38.9894 mL
	5 mM	0.3119 mL	1.5596 mL	3.1192 mL	7.7979 mL
	10 mM	0.1560 mL	0.7798 mL	1.5596 mL	3.8989 mL
	15 mM	0.1040 mL	0.5199 mL	1.0397 mL	2.5993 mL
	20 mM	0.0780 mL	0.3899 mL	0.7798 mL	1.9495 mL
	25 mM	0.0624 mL	0.3119 mL	0.6238 mL	1.5596 mL
	30 mM	0.0520 mL	0.2599 mL	0.5199 mL	1.2996 mL
	40 mM	0.0390 mL	0.1949 mL	0.3899 mL	0.9747 mL
	50 mM	0.0312 mL	0.1560 mL	0.3119 mL	0.7798 mL
	60 mM	0.0260 mL	0.1300 mL	0.2599 mL	0.6498 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.