1. Membrane Transporter/Ion Channel
  2. P2X Receptor
  3. AZ10606120 dihydrochloride

AZ10606120 dihydrochloride 

Cat. No.: HY-108669 Purity: 99.04%
Handling Instructions

AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth.

For research use only. We do not sell to patients.

AZ10606120 dihydrochloride Chemical Structure

AZ10606120 dihydrochloride Chemical Structure

CAS No. : 607378-18-7

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5 mg USD 165 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of ~10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1].

IC50 & Target

IC50: ~10 nM (P2X7R)[1]

Molecular Weight

495.48

Formula

C₂₅H₃₆Cl₂N₄O₂

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (16.81 mM; Need ultrasonic)

H2O : 2 mg/mL (4.04 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0182 mL 10.0912 mL 20.1824 mL
5 mM 0.4036 mL 2.0182 mL 4.0365 mL
10 mM 0.2018 mL 1.0091 mL 2.0182 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
AZ10606120 dihydrochloride
Cat. No.:
HY-108669
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