607378-18-7
607378-18-7
Chemical Structure
AZ10606120 dihydrochloride
- CAS No.: 607378-18-7
- Formula:C25H36Cl2N4O2
- Molecular Weight:495.48
IUPAC Name: 2-(adamantan-1-yl)-N-(2-((2-((2-hydroxyethyl)amino)ethyl)amino)quinolin-5-yl)acetamide dihydrochloride
InChIKey: BVFONFUUWORSPO-UHFFFAOYSA-N
SMILES: O=C(NC1=C2C=CC(NCCNCCO)=NC2=CC=C1)CC3(C4)CC5CC4CC(C5)C3.[H]Cl.[H]Cl
Biological Activity: AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of about 10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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AZ10606120 dihydrochloride | 99.93% | AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of about 10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth. | ||||||||||||||||||||
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AZ10606120 dihydrochloride (Standard) | ≥98% | AZ10606120 dihydrochloride (Standard) is the analytical standard of AZ10606120 (dihydrochloride) (HY-108669). This product is intended for research and analytical applications. AZ10606120 dihydrochloride is a selective, high affinity antagonist for P2X7 receptor (P2X7R) at human and rat with an IC50 of about 10 nM. AZ10606120 dihydrochloride is little or no effect at other P2XR subtypes. AZ10606120 dihydrochloride has anti-depressant effects and reduces tumour growth. | ||||||||||||||||||||
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References
