2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Calcium Channel
  4. D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt

D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt  (Synonyms: Ins(1,2,4,5)P4 tetrasodium salt; 1,2,4,5-IP4 tetrasodium salt)

Cat. No.: HY-173537
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D-myo-Inositol-1,2,4,5-tetraphosphate (DL-Ins-(1,2,4,5)P4) tetrasodium is raracemic regioisomer of myo-inositol tetrakisphosphates (IP4s). D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium is an Ins(1,4,5)P3 receptor agonist with a Ki of 11 nM. D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium induces Ca2+ mobilization with an EC50 value of 0.22 μM in CHO cells.

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D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt

D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt Chemical Structure

CAS No. : 154278-46-3

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D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt Related Antibodies

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Description

D-myo-Inositol-1,2,4,5-tetraphosphate (DL-Ins-(1,2,4,5)P4) tetrasodium is raracemic regioisomer of myo-inositol tetrakisphosphates (IP4s). D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium is an Ins(1,4,5)P3 receptor agonist with a Ki of 11 nM. D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium induces Ca2+ mobilization with an EC50 value of 0.22 μM in CHO cells[1].

Molecular Weight

588.00

Formula

C6H12Na4O18P4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H]([C@@H]([C@H]([C@H]([C@H]1OP(O)(O[Na])=O)OP(O)(O[Na])=O)O)OP(O)(O[Na])=O)OP(O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (85.03 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7007 mL 8.5034 mL 17.0068 mL
5 mM 0.3401 mL 1.7007 mL 3.4014 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.7007 mL 8.5034 mL 17.0068 mL 42.5170 mL
5 mM 0.3401 mL 1.7007 mL 3.4014 mL 8.5034 mL
10 mM 0.1701 mL 0.8503 mL 1.7007 mL 4.2517 mL
15 mM 0.1134 mL 0.5669 mL 1.1338 mL 2.8345 mL
20 mM 0.0850 mL 0.4252 mL 0.8503 mL 2.1259 mL
25 mM 0.0680 mL 0.3401 mL 0.6803 mL 1.7007 mL
30 mM 0.0567 mL 0.2834 mL 0.5669 mL 1.4172 mL
40 mM 0.0425 mL 0.2126 mL 0.4252 mL 1.0629 mL
50 mM 0.0340 mL 0.1701 mL 0.3401 mL 0.8503 mL
60 mM 0.0283 mL 0.1417 mL 0.2834 mL 0.7086 mL
80 mM 0.0213 mL 0.1063 mL 0.2126 mL 0.5315 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium salt Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

D-myo-Inositol-1,2,4,5-tetraphosphate tetrasodium154278-46-3Ins(1,2,4,5)P4 tetrasodium 1,2,4,5-IP4 tetrasodiumCalcium ChannelCa2+ channelsCa channelsIns(1,4,5)P3 receptor agonistCa2+ mobilizationInhibitorinhibitorinhibit

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