2. Autophagy Neuronal Signaling
  3. PINK1/Parkin
  4. Kinetin triphosphate tetrasodium

Kinetin triphosphate tetrasodium  (Synonyms: 6-Fu-ATP tetrasodium; KTP tetrasodium)

Cat. No.: HY-134398A
Handling Instructions

Molarity Calculator

Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research.

For research use only. We do not sell to patients.

Kinetin triphosphate tetrasodium Chemical Structure

Kinetin triphosphate tetrasodium Chemical Structure

Size Price Stock Quantity
1 mg USD 180 In-stock
5 mg USD 460 In-stock
10 mg USD 750 In-stock
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100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of Kinetin triphosphate tetrasodium:

Kinetin triphosphate tetrasodium Related Antibodies

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Description

Kinetin triphosphate(6-Fu-ATP) tetrasodium is an ATP analogue that regulates or enhances kinase function with higher catalytic efficiency than its endogenous substrate, ATP. Kinetin triphosphate tetrasodium can be used in Parkinson's disease research[1].

In Vitro

Kinetin triphosphate tetrasodium can act as a phosphate donor for PINK1 to recognize the T257 autophosphorylation site, and can restore the catalytic activity of PINK1 G309D to close to WT levels in HeLa cells in vitro[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Kinetin triphosphate tetrasodium Related Antibodies
Molecular Weight

675.19

Formula

C15H16N5Na4O14P3
Appearance

Solid

Color

White to off-white

SMILES

O=P(O[Na])(O[Na])OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(NCC4=CC=CO4)=C3N=C2)[C@H](O)[C@@H]1O)(O[Na])=O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (370.27 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4811 mL 7.4053 mL 14.8106 mL
5 mM 0.2962 mL 1.4811 mL 2.9621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.4811 mL 7.4053 mL 14.8106 mL 37.0266 mL
5 mM 0.2962 mL 1.4811 mL 2.9621 mL 7.4053 mL
10 mM 0.1481 mL 0.7405 mL 1.4811 mL 3.7027 mL
15 mM 0.0987 mL 0.4937 mL 0.9874 mL 2.4684 mL
20 mM 0.0741 mL 0.3703 mL 0.7405 mL 1.8513 mL
25 mM 0.0592 mL 0.2962 mL 0.5924 mL 1.4811 mL
30 mM 0.0494 mL 0.2468 mL 0.4937 mL 1.2342 mL
40 mM 0.0370 mL 0.1851 mL 0.3703 mL 0.9257 mL
50 mM 0.0296 mL 0.1481 mL 0.2962 mL 0.7405 mL
60 mM 0.0247 mL 0.1234 mL 0.2468 mL 0.6171 mL
80 mM 0.0185 mL 0.0926 mL 0.1851 mL 0.4628 mL
100 mM 0.0148 mL 0.0741 mL 0.1481 mL 0.3703 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Kinetin triphosphate tetrasodium Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Kinetin triphosphate tetrasodium6-Fu-ATP tetrasodiumKTP tetrasodiumPINK1/ParkinATP analogueParkinson's diseasecatalyticInhibitorinhibitorinhibit

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