8-Br-GTP tetrasodium
8-Br-GTP (tetrasodium) (8-Bromoguanosine-5'-triphosphate (tetrasodium)) is a derivative of the energy substrate – GTP, for protein synthesis and gluconeogenesis. 8-Br-GTP (tetrasodium) inhibits the E. coli GTPase FtsZ with a Ki of 31.8 μM. 8-Br-GTP (tetrasodium) promotes the assembly of porcine brain microtubules.
For research use only. We do not sell to patients.
- Formula: C10H11BrN5Na4O14P3
- Molecular Weight:690.00
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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Molecular Weight 690.00
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Formula C10H11BrN5Na4O14P3
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SMILES
O=P(OP(OP(O[Na])(O[Na])=O)(O[Na])=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(Br)=NC3=C2NC(N)=NC3=O)O1)O[Na]
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Synonyms
8-Bromoguanosine-5'-triphosphate tetrasodium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Läppchen, T., et al., (2005). GTP analogue inhibits polymerization and GTPase activity of the bacterial protein FtsZ without affecting its eukaryotic homologue tubulin. Biochemistry, 44(21), 7879–7884. [Content Brief]
[2]. Muraoka, M., et al., (1999). The effects of various GTP analogues on microtubule assembly. Cell structure and function, 24(2), 101–109. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)