1. Anti-infection
  2. Bacterial
  3. 8-Br-GTP

8-Br-GTP (Synonyms: 8-Bromoguanosine-5'-triphosphate)

Cat. No.: HY-134274
Handling Instructions

8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification.

For research use only. We do not sell to patients.

8-Br-GTP Chemical Structure

8-Br-GTP Chemical Structure

CAS No. : 23197-98-0

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Description

8-Br-GTP, a GTP analog, is a competitive FtsZ polymerization and GTPase activity (Ki of 31.8 μM) inhibitor. 8-Br-GTP can be used for nucleic acid modification[1].

In Vitro

8-Br-GTP inhibits FtsZ polymerization but does not affect tubulin polymerization.8-Br-GTP has two stable orientations of the base toward the sugar: anti and syn. 8-Br-GTP shows preference for the syn conformation (population ~90%)[1][2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

602.08

Formula

C₁₀H₁₅BrN₅O₁₄P₃

CAS No.

23197-98-0

SMILES

O[[email protected]@H]([[email protected]@H](O)[[email protected]@](N1C(Br)=NC2=C1NC(N)=NC2=O)([H])O3)[[email protected]]3COP(O)(OP(OP(O)(O)=O)(O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

8-Br-GTP8-Bromoguanosine-5'-triphosphateBacterialFtsZpolymerizationGTPasenucleicacidanti-bacterialInhibitorinhibitorinhibit

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8-Br-GTP
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