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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
60 Results for "
SMMC 7721
" in MedChemExpress (MCE) Product Catalog:
Products (60)
60 Results for "SMMC 7721" in MCE Product Catalog:
16
16 Cited Publications
Synonyms: 5,7-Dihydroxy-4'-methoxyflavone
3
3 Cited Publications
Cat. No.: HY-N2303
CAS No.: 84745-95-9
2
2 Cited Publications
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14-3-3η Protein inhibitor 1 (Compound C11) is a 14-3-3η protein inhibitor with a KD of 35 µM. 14-3-3η Protein inhibitor 1 shows inhibitory activities against several typical human liver cancer cell lines. 14-3-3η Protein inhibitor 1 induces cell apoptosis and G1-S cell cycle arrest with good metabolic stability .
1
1 Cited Publications
Cat. No.: HY-N2116
CAS No.: 111047-30-4
1
1 Cited Publications
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Zardaverine is an orally active and selective PDE3/4 inhibitor (IC50)=0.58 uM/0.17 uM) with potent bronchodilator activity. Zardaverine also selectively inhibits the proliferation of HCC cells and induces apoptosis and cycle arrest (G0/G1 phase). Zardaverine has good antitumor potential and is effective in both bronchial relaxation and reduction of inflammation in asthma .
1
1 Cited Publications
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Cat. No.: HY-P11308
CAS No.: 1421680-54-7
Cat. No.: HY-N4048
CAS No.: 133453-58-4
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Cat. No.: HY-N7022
CAS No.: 158511-59-2
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Cat. No.: HY-146350
CAS No.: 2414906-32-2
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TrxR-IN-4 is a thioredoxin reductase (TrxR) inhibitor with a rat IC50 of 0.37 μM. TrxR-IN-4 inhibits TrxR activity, elevates reactive oxygen species (ROS) and induces apoptosis. TrxR-IN-4 mediates endoplasmic reticulum stress and induces mitochondrial dysfunction. TrxR-IN-4 can be used for the research of hepatocellular carcinoma .
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Alkaloids Piperidine Alkaloids Dicranostigma leptopodum (Maxim.) Fedde Plants Disease Research Fields Papaveraceae Cancer
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Cat. No.: HY-N16067
CAS No.: 1442381-95-4
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Cat. No.: HY-131055
CAS No.: 105049-15-8
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Mytoxin B is an ADC cytotoxin. Mytoxin B is a satratoxin-type trichothecene macrolide and is similar to the effect of LY294002 (HY-10108). Mytoxin B induces cell apoptosis via PI3K/Akt pathway .
Cat. No.: HY-N10877
CAS No.: 1461760-59-7
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Cat. No.: HY-178918
CAS No.: 1282141-20-1
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XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase (HADH) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 (CBX4) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma .
Cat. No.: HY-W106860
CAS No.: 51761-07-0
Synonyms: 3-Formylcarbazole
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Cat. No.: HY-N3722
CAS No.: 123497-84-7
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Cat. No.: HY-145290
CAS No.: 2968315-02-6
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CPT-Se3, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT–Se3 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se3 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.19-4.7 μM) .
Cat. No.: HY-145291
CAS No.: 2968315-03-7
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CPT-Se4, a selenoproagent of Camptothecin (CPT), shows improved potency in killing cancer cells and inhibiting tumor growth. CPT-Se4 decreases the GSH/GSSG ratio and total thiols, elevates the ROS level in Hep G2 cells, and eventually induces apoptosis of cancer cells. CPT-Se4 shows cytotoxicity against HeLa, Hep G2, A549, and SMMC-7721 cells (IC50= 2.54-6.4 μM) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
