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Cat. No.: HY-N15612

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5-Hydroxy-7-methoxycoumarin

5-Hydroxy-7-methoxycoumarin is a coumarin compound present in the whole plant of Euphorbia kansuensis, with an IC₅₀ > 40 μM against five human cancer cell lines.

For research use only. We do not sell to patients.

CAS No.: 23053-61-4
Formula: C₁₀H₈O₄
Molecular Weight:192.17

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

5-Hydroxy-7-methoxycoumarin Chemical Structure

CAS No.: 23053-61-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

5-Hydroxy-7-methoxycoumarin is a coumarin compound present in the whole plant of Euphorbia kansuensis, with an IC₅₀ > 40 μM against five human cancer cell lines^[1].

In Vitro

5-Hydroxy-7-methoxycoumarin (0.0625-40 μM; 48 h) exhibits no significant activity against human cancer cell lines in vitro^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:

HL-60 (human myeloid leukemia), SMMC-7721 (hepatocellular carcinoma), A-549 (human lung cancer), MCF-7 (human breast carcinoma), SW-480 (colon cancer)
Concentration:

0.0625, 0.32, 1.6, 8, 40 μM
Incubation Time:

48 h
Result:

Showed no cytotoxic activity against all tested human cancer cell lines, with an IC₅₀ value > 40 μM.

Chemical Information

CAS No. 23053-61-4
Molecular Weight 192.17
Formula C₁₀H₈O₄
SMILES

O=C1OC=2C=C(OC)C=C(O)C2C=C1
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang BY, et al. Chemical constituents of Euphorbia tangutica. Nat Prod Res. 2012;26(24):2309-2315. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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