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Art. -Nr.: HY-D3206

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CuFS

CuFS is a reaction-based fluorescent sensor for detecting Cu²⁺ with zero background fluorescence. CuFS acts as a fluorescence quencher in the absence of Cu²⁺ and as a fluorescence enhancer in the presence of Cu²⁺. CuFS can be fabricated into test strips and applied to the detection of Cu²⁺ in human cancer cells.

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CAS. Nr.: 1860808-05-4
Formel: C₂₀H₁₉N₅O₆S
Molecular Weight:457.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CuFS Chemical Structure

CAS. Nr.: 1860808-05-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

CuFS (10 μM; 30 min at room temperature) shows almost zero background fluorescence in PBS containing 20% THF. After reaction with 22 μM Cu²⁺, it produces an 811-fold fluorescence enhancement centered at 469 nm. Its detection limit for Cu²⁺ is 12.3 nM, with a linear response range from 12.3 nM to 2.0 μM^[1].
CuFS (0-20 μM; incubated at 37 °C for 30 min) exhibits negligible background fluorescence and induces concentration-dependent fluorescence enhancement in human hepatocellular carcinoma SMMC-7721 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1860808-05-4
Molecular Weight 457.46
Formel C₂₀H₁₉N₅O₆S
SMILES

CCN(C1=CC=C2C=C(C(OC2=C1)=O)C(NNC3=CC=C(C=C3[N+]([O-])=O)[N+]([O-])=O)=S)CC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Long L, et al. Complete suppression of the fluorophore fluorescence by combined effect of multiple fluorescence quenching groups: A fluorescent sensor for Cu²⁺ with zero background signals. Anal Chim Acta. 2016;908:1-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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