CuFS
CuFS is a reaction-based fluorescent sensor for detecting Cu2+ with zero background fluorescence. CuFS acts as a fluorescence quencher in the absence of Cu2+ and as a fluorescence enhancer in the presence of Cu2+. CuFS can be fabricated into test strips and applied to the detection of Cu2+ in human cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 1860808-05-4
- Formula: C20H19N5O6S
- Molecular Weight:457.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
CuFS (10 μM; 30 min at room temperature) shows almost zero background fluorescence in PBS containing 20% THF. After reaction with 22 μM Cu2+, it produces an 811-fold fluorescence enhancement centered at 469 nm. Its detection limit for Cu2+ is 12.3 nM, with a linear response range from 12.3 nM to 2.0 μM[1].
CuFS (0-20 μM; incubated at 37 °C for 30 min) exhibits negligible background fluorescence and induces concentration-dependent fluorescence enhancement in human hepatocellular carcinoma SMMC-7721 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1860808-05-4
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Molecular Weight 457.46
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Formula C20H19N5O6S
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SMILES
CCN(C1=CC=C2C=C(C(OC2=C1)=O)C(NNC3=CC=C(C=C3[N+]([O-])=O)[N+]([O-])=O)=S)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CuFS Related Classifications
HY-D3206 Related Classifications
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