358 Results for "

carbonyls

" in MedChemExpress (MCE) Product Catalog:
Products (358)

358 Results for "carbonyls" in MCE Product Catalog:

102
102 Publications Verification
Cat. No.: HY-66019
CAS No.: 3326-32-7
Synonyms: Fluorescein 5-isothiocyanate
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
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4
4 Cited Publications
Cat. No.: HY-128851
CAS No.: 85-61-0
Purity:  94.29%
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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4
4 Cited Publications
Cat. No.: HY-128851A
CAS No.: 18439-24-2
Purity:  95.40%
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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4
4 Cited Publications
Cat. No.: HY-128851B
CAS No.: 55672-92-9
Purity:  99.46%
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .
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2
2 Cited Publications
Cat. No.: HY-100215
CAS No.: 66640-86-6
Purity:  98.71%
Biotin Hydrazide is a carbonyl-reactive biotinylation reagent, which is a carbonyl probe.
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2
2 Cited Publications
Cat. No.: HY-N0548
CAS No.: 591-12-8
α-Angelica lactone is a naturally occurring anticarcinogen and an vinylogous nucleophile. α-Angelica lactone can give the chiral δ-amino γ,γ-disubstituted butenolide carbonyl derivatives and exhibitselectrophilic trapping at the γ-carbon. α-Angelica lactone exerts strong chemoprotective effects by selective enhancement of glutathione-S-thansferase (GST) and UDP-glucononosyltransferase (UGT) detoxification enzymes .
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2
2 Cited Publications
Cat. No.: HY-15941
CAS No.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
5(6)-FITC (Fluorescein 5(6)-isothiocyanate) is an amine-reactive derivative of a fluorescent dye, characterized by high absorbance and excellent fluorescence quantum yield. The isothiocyanate group of FITC can react with various functional groups on proteins, including amines, thiols, imidazoles, tyrosines and carbonyls, enabling the labeling of proteins such as antibodies and lectins. 5(6)-FITC has a wide range of applications, including flow cytometry, immunofluorescence, protease assays and conjugation. The maximum excitation/emission wavelengths are 492/518 nm .
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1
1 Cited Publications
Cat. No.: HY-Y1147
CAS No.: 141-05-9
Synonyms: Maleic acid diethyl ester
Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO -. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3].
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1
1 Cited Publications
Cat. No.: HY-109001
CAS No.: 1254698-46-8
Purity:  ≥98.0%
Synonyms: ABT-957
Target:  

Proteasome

Research Areas:  

Neurological Disease

Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential application of Alzheimer's disease (AD) . Alicapistat mitigates the metabolic liability of carbonyl reduction and inhibits calpain 1 with an IC50 value of 395 nM .
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Cat. No.: HY-111434A
CAS No.: 1994331-17-7
Purity:  ≥98.0%
Synonyms: UAA crosslinker 1 hydrochloride
Research Areas:  

Cancer

N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride (UAA crosslinker 1 hydrochloride) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy)carbonyl]-L-lysine hydrochloride is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research .
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Cat. No.: HY-W048727
CAS No.: 135248-89-4
Research Areas:  

Others

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-cysteine is a cysteine derivative .
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Cat. No.: HY-76440
CAS No.: 6704-31-0
Synonyms: Oxetan-3-one
3-Oxetanone (Oxetan-3-one) is a four-membered cyclic ketone and strained cyclic ether derivative with measurable molecular g-value, magnetic susceptibility anisotropy and molecular quadrupole moment. 3-Oxetanone acts not only as a hydrogen bond acceptor, a tetrel donor and a weak hydrogen bond acceptor, but also forms a classic O-H···O hydrogen bond with H2O via the ether oxygen atom. Alternatively, it forms a C···O tetrel bond with formaldehyde using its carbonyl group as a tetrel donor, while acting as a proton acceptor to form a C-H···O weak hydrogen bond with formaldehyde. 3-Oxetanone can be used to prepare various oxetanes .
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Cat. No.: HY-W013182
CAS No.: 119062-05-4
Research Areas:  

Others

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-aspartic acid is an aspartic acid derivative .
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Cat. No.: HY-D0099
CAS No.: 76863-28-0
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .
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Cat. No.: HY-124197
CAS No.: 113707-87-2
Purity:  97.11%
Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .
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Cat. No.: HY-111434
CAS No.: 1167421-25-1
Purity:  ≥98.0%
Synonyms: UAA crosslinker 1
Research Areas:  

Cancer

N6-[(2-Azidoethoxy) carbonyl]-L-lysine (UAA crosslinker 1) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy) carbonyl]-L-lysine mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy) carbonyl]-L-lysine is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research .
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Cat. No.: HY-23185
CAS No.: 16966-09-9
Research Areas:  

Others

N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonine is a threonine derivative .
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Cat. No.: HY-W048911
CAS No.: 116611-64-4
Research Areas:  

Others

(((9H-Fluoren-9-yl)methoxy)carbonyl)-L-histidine is a histidine derivative .
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Cat. No.: HY-W008731
CAS No.: 2566-19-0
Research Areas:  

Others

2-(2-(((Benzyloxy)carbonyl)amino)acetamido)acetic acid is a Glycine (HY-Y0966) derivative .
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Cat. No.: HY-W090626
CAS No.: 110990-08-4
Research Areas:  

Others

(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-lysine is a lysine derivative .
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