trans-2-Hexenal
Based on 1 Customer Validation
trans-2-Hexenal ((E)-2-Hexenal) is a volatile compound widely present in fresh plants, vegetables, and fruits, with a unique leafy aroma. trans-2-Hexenal has antifungal activity and can also inhibit the germination of soybean seeds and the growth of seedlings. In addition, trans-2-Hexenal can be used to determine low-molecular-weight carbonyl compounds that are reactive with biological nucleophiles in biological samples.
For research use only. We do not sell to patients.
- Purity: 99.65%
- CAS No.: 6728-26-3
- Formula: C6H10O
- Molecular Weight:98.15
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
trans-2-Hexenal (0-6 h) can inhibit the germination of soybean seeds and the growth of seedlings[2].
trans-2-Hexenal (0-320 μL/L; 48 h) can inhibit the mycelial growth of P. cyclopium with an MIC of 160 μL/L, an MFC of 320 μL/L, and an ED50 of 39.42 μL/L[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 6728-26-3
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Appearance Liquid (Density: 0.828±0.06 g/cm3)
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Molecular Weight 98.15
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Formula C6H10O
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Color Colorless to light yellow
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SMILES
CCC/C=C/C=O
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Synonyms
(E)-2-Hexenal
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 50 mg/mL (509.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (25.47 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: 2.5 mg/mL (25.47 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (269 KB)
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SDS (572 KB)
- English - EN (572 KB)
- Français - FR (572 KB)
- Deutsch - DE (572 KB)
- Norwegian - NO (572 KB)
- Español - ES (572 KB)
- Swedish - SV (572 KB)
- Italian - IT (572 KB)
- Korean - KR (572 KB)
- Portuguese - PT (572 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 10.1885 mL | 50.9424 mL | 101.8849 mL | 254.7122 mL |
| 5 mM | 2.0377 mL | 10.1885 mL | 20.3770 mL | 50.9424 mL | |
| 10 mM | 1.0188 mL | 5.0942 mL | 10.1885 mL | 25.4712 mL | |
| 15 mM | 0.6792 mL | 3.3962 mL | 6.7923 mL | 16.9808 mL | |
| 20 mM | 0.5094 mL | 2.5471 mL | 5.0942 mL | 12.7356 mL | |
| 25 mM | 0.4075 mL | 2.0377 mL | 4.0754 mL | 10.1885 mL | |
| 30 mM | 0.3396 mL | 1.6981 mL | 3.3962 mL | 8.4904 mL | |
| 40 mM | 0.2547 mL | 1.2736 mL | 2.5471 mL | 6.3678 mL | |
| 50 mM | 0.2038 mL | 1.0188 mL | 2.0377 mL | 5.0942 mL | |
| 60 mM | 0.1698 mL | 0.8490 mL | 1.6981 mL | 4.2452 mL | |
| 80 mM | 0.1274 mL | 0.6368 mL | 1.2736 mL | 3.1839 mL | |
| 100 mM | 0.1019 mL | 0.5094 mL | 1.0188 mL | 2.5471 mL |
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