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Cat. No.: HY-157452

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(8S)-Methyl zearalenone

(8S)-Methyl zearalenone (ZEA analogue 5) is a selective CBR1 (carbonyl reductase 1) inhibitor, with an IC₅₀ of 0.21 μM.

For research use only. We do not sell to patients.

CAS No.: 1137720-39-8
Formula: C₁₉H₂₄O₅
Molecular Weight:332.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

(8S)-Methyl zearalenone Chemical Structure

CAS No.: 1137720-39-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

(8S)-Methyl zearalenone (ZEA analogue 5) is a selective CBR1 (carbonyl reductase 1) inhibitor, with an IC₅₀ of 0.21 μM^[1].

All Carbonyl Reductase Isoforms :

CBR1
CBR3

Chemical Information

CAS No. 1137720-39-8
Molecular Weight 332.39
Formula C₁₉H₂₄O₅
SMILES

OC1=C2C(/C=C/CC[C@H](C)C(CCC[C@@H](OC2=O)C)=O)=CC(O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Tobias J Zimmermann, et al. Discovery of a potent and selective inhibitor for human carbonyl reductase 1 from propionate scanning applied to the macrolide zearalenone. Bioorg Med Chem. 2009 Jan 15;17(2):530-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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(8S)-Methyl zearalenone

All Carbonyl Reductase Isoforms