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  3. N1,N5-Bis-boc-spermidine

N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

For research use only. We do not sell to patients.

N1,N5-Bis-boc-spermidine

N1,N5-Bis-boc-spermidine Chemical Structure

CAS No. : 68076-39-1

Size Price Stock Quantity
Solid or liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
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Description

N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
> 100 μM
Compound: 3b
Antikinetoplastid activity against Leishmania donovani LV9 axenic amastigotes in mouse RAW264.7 cells assessed as viability measured 24 hrs by SYBR green assay
Antikinetoplastid activity against Leishmania donovani LV9 axenic amastigotes in mouse RAW264.7 cells assessed as viability measured 24 hrs by SYBR green assay
[PMID: 25499437]
Molecular Weight

345.48

Formula

C17H35N3O4

CAS No.
Appearance

Viscous Liquid

Color

Colorless to off-white

SMILES

NCCCN(C(OC(C)(C)C)=O)CCCCNC(OC(C)(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (289.45 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8945 mL 14.4726 mL 28.9452 mL
5 mM 0.5789 mL 2.8945 mL 5.7890 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8945 mL 14.4726 mL 28.9452 mL 72.3631 mL
5 mM 0.5789 mL 2.8945 mL 5.7890 mL 14.4726 mL
10 mM 0.2895 mL 1.4473 mL 2.8945 mL 7.2363 mL
15 mM 0.1930 mL 0.9648 mL 1.9297 mL 4.8242 mL
20 mM 0.1447 mL 0.7236 mL 1.4473 mL 3.6182 mL
25 mM 0.1158 mL 0.5789 mL 1.1578 mL 2.8945 mL
30 mM 0.0965 mL 0.4824 mL 0.9648 mL 2.4121 mL
40 mM 0.0724 mL 0.3618 mL 0.7236 mL 1.8091 mL
50 mM 0.0579 mL 0.2895 mL 0.5789 mL 1.4473 mL
60 mM 0.0482 mL 0.2412 mL 0.4824 mL 1.2061 mL
80 mM 0.0362 mL 0.1809 mL 0.3618 mL 0.9045 mL
100 mM 0.0289 mL 0.1447 mL 0.2895 mL 0.7236 mL
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N1,N5-Bis-boc-spermidine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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N1,N5-Bis-boc-spermidine
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