N1,N5-Bis-boc-spermidine
Based on 1 Customer Validation
N1,N5-Bis-Boc-spermidine is a linker containing an amino group with two Boc-protected amino groups. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine.
For research use only. We do not sell to patients.
- Purity: 99.78%
- CAS No.: 68076-39-1
- Formula: C17H35N3O4
- Molecular Weight:345.48
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
>100 μM
Compound: 3b
|
Antikinetoplastid activity against Leishmania donovani LV9 axenic amastigotes in mouse RAW264.7 cells assessed as viability measured 24 hrs by SYBR green assay
Antikinetoplastid activity against Leishmania donovani LV9 axenic amastigotes in mouse RAW264.7 cells assessed as viability measured 24 hrs by SYBR green assay
|
[PMID: 25499437] |
Chemical Information
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CAS No. 68076-39-1
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Appearance Viscous Liquid
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Molecular Weight 345.48
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Formula C17H35N3O4
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Color Colorless to off-white
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SMILES
NCCCN(C(OC(C)(C)C)=O)CCCCNC(OC(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (289.45 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8945 mL | 14.4726 mL | 28.9452 mL | 72.3631 mL |
| 5 mM | 0.5789 mL | 2.8945 mL | 5.7890 mL | 14.4726 mL | |
| 10 mM | 0.2895 mL | 1.4473 mL | 2.8945 mL | 7.2363 mL | |
| 15 mM | 0.1930 mL | 0.9648 mL | 1.9297 mL | 4.8242 mL | |
| 20 mM | 0.1447 mL | 0.7236 mL | 1.4473 mL | 3.6182 mL | |
| 25 mM | 0.1158 mL | 0.5789 mL | 1.1578 mL | 2.8945 mL | |
| 30 mM | 0.0965 mL | 0.4824 mL | 0.9648 mL | 2.4121 mL | |
| 40 mM | 0.0724 mL | 0.3618 mL | 0.7236 mL | 1.8091 mL | |
| 50 mM | 0.0579 mL | 0.2895 mL | 0.5789 mL | 1.4473 mL | |
| 60 mM | 0.0482 mL | 0.2412 mL | 0.4824 mL | 1.2061 mL | |
| 80 mM | 0.0362 mL | 0.1809 mL | 0.3618 mL | 0.9045 mL | |
| 100 mM | 0.0289 mL | 0.1447 mL | 0.2895 mL | 0.7236 mL |