CBR1-IN-3
Based on 1 Customer Validation
CBR1-IN-3 (compound 13h) is a potent inhibitor of carbonyl reductase 1 (CBR1), with IC50 value of 0.034 μM.
For research use only. We do not sell to patients.
- Purity : 98.71%
- CAS No.: 891101-69-2
- Formula: C16H11ClN2O3
- Molecular Weight:314.72
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
IC50 & Target
0.034 μM (CBR1)[1]
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CWR22R | IC50 |
3.3 μM
Compound: 2e
|
Antagonistic activity at AR in human 22Rv1 cells assessed as reduction in cell number by CCK8 assay
Antagonistic activity at AR in human 22Rv1 cells assessed as reduction in cell number by CCK8 assay
|
[PMID: 32847363] |
Chemical Information
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CAS No. 891101-69-2
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Appearance Solid
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Molecular Weight 314.72
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Formula C16H11ClN2O3
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Color Light yellow to brown
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SMILES
O=C(C(C1=N)=CC2=C(O1)C(O)=CC=C2)NC3=CC=CC=C3Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)