N,N'-Carbonyldiimidazole
Based on 1 Customer Validation
N,N'-Carbonyldiimidazole (1,1'-Carbonyldiimidazole) is a highly reactive carboxylating reagent that can activate hydroxyl groups to form reactive carbonyl groups. N,N'-Carbonyldiimidazole can be used as a coupling agent and a peptide synthesis reagent.
For research use only. We do not sell to patients.
- Purity : 99.9%
- CAS No.: 530-62-1
- Formula: C7H6N4O
- Molecular Weight:162.15
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Storage:
RT, protect from light, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
Biological Activity
Description
In Vitro
N,N'-Carbonyldiimidazole is a highly reactive reagent that can mediate the conjugation of ovalbumin with magnetite nanoparticles for vaccine delivery[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 530-62-1
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Appearance Solid
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Molecular Weight 162.15
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Formula C7H6N4O
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Color White to off-white
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SMILES
O=C(N1C=NC=C1)N2C=NC=C2
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Synonyms
1,1'-Carbonyldiimidazole
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (616.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (287 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
[1]. Ho J, et al. N,N'-Carbonyldiimidazole-mediated functionalization of superparamagnetic nanoparticles as vaccine carrier. Colloids Surf B Biointerfaces. 2011 Mar;83(1):83-90. [Content Brief]
[2]. Huang Q, et al. Preparation and cyclodextrin solubilization of the antibacterial agent benzoyl metronidazole. ScientificWorldJournal. 2013 Jul 21;2013:306476. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1671 mL | 30.8356 mL | 61.6713 mL | 154.1782 mL |
| 5 mM | 1.2334 mL | 6.1671 mL | 12.3343 mL | 30.8356 mL | |
| 10 mM | 0.6167 mL | 3.0836 mL | 6.1671 mL | 15.4178 mL | |
| 15 mM | 0.4111 mL | 2.0557 mL | 4.1114 mL | 10.2785 mL | |
| 20 mM | 0.3084 mL | 1.5418 mL | 3.0836 mL | 7.7089 mL | |
| 25 mM | 0.2467 mL | 1.2334 mL | 2.4669 mL | 6.1671 mL | |
| 30 mM | 0.2056 mL | 1.0279 mL | 2.0557 mL | 5.1393 mL | |
| 40 mM | 0.1542 mL | 0.7709 mL | 1.5418 mL | 3.8545 mL | |
| 50 mM | 0.1233 mL | 0.6167 mL | 1.2334 mL | 3.0836 mL | |
| 60 mM | 0.1028 mL | 0.5139 mL | 1.0279 mL | 2.5696 mL | |
| 80 mM | 0.0771 mL | 0.3854 mL | 0.7709 mL | 1.9272 mL | |
| 100 mM | 0.0617 mL | 0.3084 mL | 0.6167 mL | 1.5418 mL |