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  3. N4,N9-di-Boc-spermine

N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.

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N4,N9-di-Boc-spermine

N4,N9-di-Boc-spermine Chemical Structure

CAS No. : 177213-61-5

Size Price Stock Quantity
Solid or liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid or liquid
25 mg In-stock
50 mg In-stock
100 mg In-stock
250 mg In-stock
1 g In-stock
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10 g   Get quote  

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Description

N4, N9-di-Boc-spermine is a spermine linker containing two a Boc-protected amino groups and two amine groups. The Boc groups can be deprotected under mild acidic conditions to form the free amine. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Spermidine is a polyamine that modulates various cellular activities like cellular development and differentiation, stability of DNA, and apoptosis.

Molecular Weight

402.57

Formula

C20H42N4O4

CAS No.
Appearance

Viscous Liquid

Color

Colorless to light yellow

SMILES

O=C(N(CCCCN(CCCN)C(OC(C)(C)C)=O)CCCN)OC(C)(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (248.40 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4840 mL 12.4202 mL 24.8404 mL
5 mM 0.4968 mL 2.4840 mL 4.9681 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4840 mL 12.4202 mL 24.8404 mL 62.1010 mL
5 mM 0.4968 mL 2.4840 mL 4.9681 mL 12.4202 mL
10 mM 0.2484 mL 1.2420 mL 2.4840 mL 6.2101 mL
15 mM 0.1656 mL 0.8280 mL 1.6560 mL 4.1401 mL
20 mM 0.1242 mL 0.6210 mL 1.2420 mL 3.1050 mL
25 mM 0.0994 mL 0.4968 mL 0.9936 mL 2.4840 mL
30 mM 0.0828 mL 0.4140 mL 0.8280 mL 2.0700 mL
40 mM 0.0621 mL 0.3105 mL 0.6210 mL 1.5525 mL
50 mM 0.0497 mL 0.2484 mL 0.4968 mL 1.2420 mL
60 mM 0.0414 mL 0.2070 mL 0.4140 mL 1.0350 mL
80 mM 0.0311 mL 0.1553 mL 0.3105 mL 0.7763 mL
100 mM 0.0248 mL 0.1242 mL 0.2484 mL 0.6210 mL
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N4,N9-di-Boc-spermine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
N4,N9-di-Boc-spermine
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